Microbial Life: Origin and Discovery
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Questions and Answers

What is the name of the first method of DNA sequencing that was developed by Fred Sanger that was fast enough to sequence large genomes?

Fred Sanger developed the first method of DNA sequencing that was fast enough to sequence large genomes, this method is known as Sanger sequencing.

Which of the following is NOT a characteristic of a microbe?

  • Can be multicellular
  • Always functions as an individual entity (correct)
  • Requires a microscope to be seen
  • A living organism
  • What is the distinguishing feature that separates prokaryotes from eukaryotes?

  • Presence of a nucleus (correct)
  • Presence of ribosomes
  • Presence of DNA
  • Presence of a cell wall
  • Viruses are considered to be acellular entities.

    <p>True</p> Signup and view all the answers

    What is the term used to describe the total genetic information of an organism?

    <p>Genome</p> Signup and view all the answers

    What type of bacteria are known as "rock-eating" bacteria, which can be involved in metal mining and degradation of stone monuments?

    <p>Lithotrophs</p> Signup and view all the answers

    The 14th century was marked by a devastating bubonic plague caused by the bacterium Yersinia pestis.

    <p>True</p> Signup and view all the answers

    The polar area chart developed by Florence Nightingale is a graphical representation of the causes of death among soldiers in the Crimean War.

    <p>True</p> Signup and view all the answers

    Who is credited with building the first compound microscope and using it to observe mold?

    <p>Robert Hooke</p> Signup and view all the answers

    What was the name of the first cellular microbe to have its genome sequenced in 1995?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    What are collections of sequences from diverse populations of microbes taken directly from the environment called?

    <p>Metagenomes</p> Signup and view all the answers

    Study Notes

    Chapter 1: Microbial Life: Origin and Discovery

    • Microbiology is an evolving science. The science focuses on microscopic organisms.

    • Microbes are living organisms requiring microscopes to be seen.

    • Most microbes are single-celled, but some are multicellular; this doesn't mean they function as independent entities.

    • Microbes vary in size from 0.2 micrometers to a few millimeters.

    • Viruses are ten times smaller than the smallest cells.

    • Each microbe contains the genetic information to reproduce its kind.

    Chapter Overview

    • The chapter explores microbes from the concept of a germ to the understanding of its genome.

    • Microbes shape human history, with implications on medical microbiology, environment, and ecology.

    • The study of microbes also involves the microbial family tree and cell biology from the viewpoint of the DNA revolution.

    1.1 From Germ to Genome: What is a Microbe?

    • Microbes are ubiquitous and include prokaryotes (bacteria, archaea), eukaryotes (algae, fungi, protists) and acellular entities (viruses and prions).

    • These organisms are categorized into three "domains": bacteria, archaea, and eukaryotes.

    • The domains evolved from a common ancestral cell.

    1.2 Microbes Shape Human History

    • Microbes have influenced human cultures since the earliest civilizations.

    • Fermentation of foods and beverages using yeasts and bacteria is an example.

    • Some bacteria and other microbes affect metalwork and erode stone structures.

    • Microbes have been responsible for diseases and famines over history.

    Microbial Disease Devastates Human Populations

    • Microbial diseases have significantly affected demographics and cultural practices throughout history.

    • The bubonic plague, caused by Yersinia pestis, had a devastating impact in the 14th century.

    • Tuberculosis, caused by Mycobacterium tuberculosis, affected populations extensively in the 19th century.

    • AIDS, caused by HIV, represents a significant health challenge in recent times.

    • Many wars have been affected by microbial illnesses, and more soldiers have died due to infections than wounds, according to the notes.

    Microscopes Reveal the Microbial World

    • Robert Hooke (1635-1703) invented and used the first compound microscope.

    • He observed mold using this microscope.

    • He published Micrographia, the first manuscript that illustrated microscopic objects.

    • Hooke coined the term "cell."

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    Description

    Explore the fascinating world of microbes in Chapter 1, which dives into their origins and discoveries. Learn about the diversity of microbial life, their roles in shaping human history, and the implications for medical microbiology, ecology, and cell biology.

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