Podcast
Questions and Answers
Which mechanism do intracellular bacteria like Mycobacterium tuberculosis use to escape into the cytosol?
Which mechanism do intracellular bacteria like Mycobacterium tuberculosis use to escape into the cytosol?
- Inhibit class I MHC–associated antigen presentation
- Remove newly synthesized class I molecules from the ER
- Block transport of antigenic peptides from the cytosol into the endoplasmic reticulum
- Inhibit fusion of phagosomes with lysosomes (correct)
What is the result of viral mechanisms that inhibit class I MHC expression?
What is the result of viral mechanisms that inhibit class I MHC expression?
- Increased loading of class I MHC molecules by viral peptides
- Increased surface expression of class I MHC molecules
- Reduced surface expression of class I MHC molecules (correct)
- Reduced loading of class I MHC molecules by viral peptides
Which cells are activated by class I-deficient cells?
Which cells are activated by class I-deficient cells?
- T lymphocytes
- B cells
- NK cells (correct)
- Phagocytes
Which process occurs in chronic viral infections where CD8+ T cells become inactivated and the virus persists?
Which process occurs in chronic viral infections where CD8+ T cells become inactivated and the virus persists?
What happens to CD8+ T cells in acute viral infections?
What happens to CD8+ T cells in acute viral infections?
What is the main difference between acute and chronic viral infections in terms of CD8+ T cell response?
What is the main difference between acute and chronic viral infections in terms of CD8+ T cell response?
Which of the following is a mechanism by which viruses establish chronic infections?
Which of the following is a mechanism by which viruses establish chronic infections?
What is the term used to describe the phenomenon in which T cells mount an initial response against a virus but the response is prematurely terminated?
What is the term used to describe the phenomenon in which T cells mount an initial response against a virus but the response is prematurely terminated?
Which of the following is an example of a virus that is able to survive in infected persons by killing CD4+ T cells?
Which of the following is an example of a virus that is able to survive in infected persons by killing CD4+ T cells?
What is one approach for tilting the balance between the host and microbes in favor of protective immunity?
What is one approach for tilting the balance between the host and microbes in favor of protective immunity?
