18 Questions
What are microRNAs (miRNAs)?
Small noncoding RNAs that regulate gene expression
How can microarrays be used to measure the expression of microRNAs?
By using probes specific to microRNAs
What are tiling arrays designed for?
Measuring the abundance of all transcribed parts of the genome
What have scientists found using tiling arrays?
Most parts of the human genome are transcribed
What is proteomics the study of?
All or many proteins
What is the major difference between cDNA microarrays and oligonucleotide microarrays?
The way the probes are prepared
How has the term 'transcriptome' changed over time?
From focusing on mRNA expression to studying all or many transcripts
Which type of microarray is also known as cDNA microarray?
cDNA microarray
What is the main function of DNA microarrays in the field of functional genomics?
Study gene expression patterns
In what type of cell can DNA microarrays be used to identify altered gene expression, such as in cancer cells?
Both prokaryotic and eukaryotic cells
What aspect of gene expression can DNA microarrays help researchers analyze?
Transcriptional regulation
Which technique can DNA microarrays complement in the study of functional genomics?
Mass Spectrometry
What is the typical application of mass spectrometry mentioned in the text?
Measuring mRNA abundances
In mass spectrometry, what does aligning the peaks between different samples allow researchers to do?
Detect differentially expressed proteins
What does ChIP-Chip technique combine ChIP with, according to the text?
DNA microarrays
What is a primary focus of ChIP-Chip technique?
Detecting transcription factor binding sites
How does ChIP-Sequencing help in studying DNA-protein interactions?
By sequencing DNAs bound by specific proteins
What does ChIP-Chip technique help in studying according to the text?
Transcription factor binding sites
This quiz covers the concepts and applications of microarrays, focusing on the measurement of microRNAs and the development of tiling arrays. Test your understanding of how microarrays are used in measuring gene expression levels.
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