Microangiopathic Hemolytic Anemia (MAHA)

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Questions and Answers

What is the primary cause of acquired erythrocyte fragmentation in Microangiopathic Hemolytic Anemia (MAHA)?

  • Hypotension leading to RBC damage
  • Excessive intake of iron supplements
  • Abnormal production of red cells
  • Forced passage of RBC through partial vascular occlusions (correct)

Which condition is characterized by the presence of fragmented red cells (schistocytes) in the blood film?

  • Iron-deficiency anemia
  • Sickle cell anemia
  • Vitamin B12 deficiency anemia
  • Thrombotic thrombocytopenic purpura (TTP) (correct)

Which condition is characterized by systemic activation of blood coagulation, resulting in generation and deposition of fibrin, leading to microvascular thrombi in various organs?

  • Malignant hypertension
  • Disseminated intravascular coagulation (DIC) (correct)
  • Scleroderma renal crisis
  • Hemolytic uremic syndrome (HUS)

Consumption of clotting factors and platelets in DIC can result in which life-threatening problem?

<p>Hemorrhage (B)</p> Signup and view all the answers

Accelerated fibrinolysis in some cases of DIC may cause severe bleeding due to:

<p>Intravascular clot formation (C)</p> Signup and view all the answers

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