Podcast
Questions and Answers
What is the brand name of Methocarbamol?
What is the brand name of Methocarbamol?
What is the drug class of Methocarbamol?
What is the drug class of Methocarbamol?
centrally acting skeletal muscle relaxant
What are the routes of administration for Methocarbamol?
What are the routes of administration for Methocarbamol?
Oral tablet: 500 mg, 750 mg
What is a common FDA indication for Methocarbamol?
What is a common FDA indication for Methocarbamol?
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What is the dosing recommendation for Methocarbamol?
What is the dosing recommendation for Methocarbamol?
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What is known about the mechanism of action of Methocarbamol?
What is known about the mechanism of action of Methocarbamol?
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Renal dose adjustment is required for Methocarbamol.
Renal dose adjustment is required for Methocarbamol.
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What is a contraindication for Methocarbamol?
What is a contraindication for Methocarbamol?
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Methocarbamol has boxed warnings.
Methocarbamol has boxed warnings.
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What are some drug interactions to be cautious of with Methocarbamol?
What are some drug interactions to be cautious of with Methocarbamol?
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What are common adverse reactions of Methocarbamol?
What are common adverse reactions of Methocarbamol?
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What are some rare but serious adverse reactions associated with Methocarbamol?
What are some rare but serious adverse reactions associated with Methocarbamol?
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What are the efficacy monitoring parameters for Methocarbamol?
What are the efficacy monitoring parameters for Methocarbamol?
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What are the toxicity monitoring parameters for Methocarbamol?
What are the toxicity monitoring parameters for Methocarbamol?
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Study Notes
Methocarbamol Overview
- Brand name: Robaxin
- Drug class: Centrally acting skeletal muscle relaxant
Administration
- Available as oral tablets in 500 mg and 750 mg dosages
Indications
- Commonly prescribed for musculoskeletal pain or muscle spasms
Dosing Information
- Initial dosing of 1500 mg by mouth four times a day for 48-72 hours
- Can titrate to 750 mg every four hours, 1500 mg three times a day, or 1000 mg four times a day
Mechanism of Action
- Exact mechanism not fully established; may involve general CNS depression
- Does not directly affect the contractile mechanisms of striated muscle, motor end plate, or nerve fibers
Renal Considerations
- No renal dose adjustment required
Contraindications
- Not suitable for individuals with hypersensitivity to methocarbamol
Warnings
- No boxed warnings associated with the drug
Drug Interactions
- Can interact with CNS depressants leading to additive sedative effects
- Caution required when using concurrently; monitor for signs of toxicity
Adverse Reactions
- Common: Somnolence or increased drowsiness
- Rare but serious: Bradyarrhythmia, hypotension, syncope, leukopenia, anaphylactoid reactions; risk of slowed or difficult breathing when combined with opioids
Monitoring Parameters
- Efficacy assessed through reduction in pain and muscle spasms
- Toxicity monitoring includes watching for severe symptoms like extreme weakness, transient quadriplegia, dizziness, or confusion shortly after initiation; assess vital signs as needed
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Description
Test your knowledge on Methocarbamol, a centrally acting skeletal muscle relaxant commonly prescribed for musculoskeletal pain. This quiz covers its dosage, administration, indications, and potential drug interactions. Assess your understanding of its mechanism, renal considerations, and contraindications.
