Metals in Biochemistry: Amino Acids and pH
44 Questions
18 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

At what pKa value will glutamic acid primarily be found in its deprotonated form?

  • 10.79
  • 8.35
  • 6.00
  • 4.25 (correct)

    • The side chain of lysine will be present as NH3+ at physiological pH.

    True (A)

    Which amino acid has a side chain pKa of 12.48?

    arginine

    The pKa of the imidazole NH group is _____, indicating it is present as NH rather than NH2+.

    <p>6.00</p> Signup and view all the answers

    Match the following amino acids with their side chain pKa values:

    <p>Glutamic acid = 4.25 Cysteine = 8.35 Lysine = 10.79 Arginine = 12.48</p> Signup and view all the answers

    Which of the following elements is associated with the molybdenum cofactor in oxo transfer proteins?

    <p>Molybdenum (C)</p> Signup and view all the answers

    The thioether of methionine is mentioned as a group associated with cobalt complex in vitamin B-12.

    <p>True (A)</p> Signup and view all the answers

    Which amino acids are mentioned as having carboxamide groups?

    <p>Glutamine and asparagine</p> Signup and view all the answers

    The amino group of __________ is a group mentioned in the content.

    <p>lysine</p> Signup and view all the answers

    Match the following chemical groups with their associated amino acids:

    <p>Carboxamide = Glutamine Thioether = Methionine Guanidine = Arginine Amino = Lysine</p> Signup and view all the answers

    Which amino acid has the abbreviation 'Cys'?

    <p>Cysteine (C)</p> Signup and view all the answers

    Arginine is one of the twenty common amino acids.

    <p>True (A)</p> Signup and view all the answers

    What is the primary structure component of proteins?

    <p>Amino acids</p> Signup and view all the answers

    The pKa is a fundamental property of an acid, whereas pH is something we can adjust; when [HA] = [A−], it indicates that _____ equals pKa.

    <p>pH</p> Signup and view all the answers

    Match the following amino acids with their abbreviations:

    <p>Alanine = Ala Asparagine = Asn Glutamine = Gln Lysine = Lys</p> Signup and view all the answers

    Which of the following amino acids has the highest molecular weight?

    <p>Arginine (C)</p> Signup and view all the answers

    The amino acid Glycine is represented by the letter 'G'.

    <p>True (A)</p> Signup and view all the answers

    The amino acid with the side chain structure containing a thiol group is called _____ .

    <p>Cysteine</p> Signup and view all the answers

    Which of the following amino acids is NOT mentioned as a ligand in the context of metal-binding groups?

    <p>Lysine (B)</p> Signup and view all the answers

    The iron complex of protoporphyrin IX is referred to as haem.

    <p>True (A)</p> Signup and view all the answers

    Name one amino acid that functions as a ligand in metal-binding groups.

    <p>Cysteine</p> Signup and view all the answers

    The ______ of histidine contains an imidazole group that acts as a ligand.

    <p>side chain</p> Signup and view all the answers

    Match the following ligands with their corresponding amino acids:

    <p>Thiolate = Cysteine Imidazole = Histidine Carboxylate = Glutamic Acid Phenolate = Tyrosine</p> Signup and view all the answers

    What role do metal-binding groups play in biology?

    <p>They assist in the transportation of oxygen. (C)</p> Signup and view all the answers

    Only carboxylates of aspartic acid serve as ligands in metal-binding groups.

    <p>False (B)</p> Signup and view all the answers

    What is the chlorin ring associated with?

    <p>Chlorophylls</p> Signup and view all the answers

    Protoporphyrin IX is an important component of _____ complexes.

    <p>iron</p> Signup and view all the answers

    Which of the following ligands is derived from tyrosine?

    <p>Phenolate (D)</p> Signup and view all the answers

    What is the primary structure of a protein defined by?

    <p>The order of amino acids in the polypeptide chain (C)</p> Signup and view all the answers

    Hydrogen bonds play a significant role in determining the tertiary structure of proteins.

    <p>False (B)</p> Signup and view all the answers

    What type of bond connects amino acids in a protein?

    <p>Peptide bonds</p> Signup and view all the answers

    The secondary structure of proteins is characterized by __________ and __________.

    <p>coils, arrows</p> Signup and view all the answers

    Which of the following correctly describes secondary protein structure?

    <p>It involves interactions between the polypeptide backbone (D)</p> Signup and view all the answers

    Match the type of protein structure to its description:

    <p>Primary = Order of amino acids in the polypeptide chain Secondary = Three-dimensional orientation due to hydrogen bonds Tertiary = Overall three-dimensional shape of a single protein Quaternary = Assembly of multiple polypeptide chains into a single protein complex</p> Signup and view all the answers

    Enterobactin is a type of peptide bond found in proteins.

    <p>False (B)</p> Signup and view all the answers

    Name the bond that connects the carbonyl oxygen of one amino acid to the amino hydrogen of another.

    <p>Hydrogen bond</p> Signup and view all the answers

    What is the primary structure of the α-helix in proteins characterized by?

    <p>Hydrogen bonds between N-H and C=O groups in the backbone (B)</p> Signup and view all the answers

    The R groups of amino acids in β-sheets alternate above and below the plane of the sheet.

    <p>True (A)</p> Signup and view all the answers

    How many amino acids are there in one complete turn of an α-helix?

    <p>3.6</p> Signup and view all the answers

    In β-sheets, the individual strands may be either __________ or __________.

    <p>parallel; antiparallel</p> Signup and view all the answers

    Match each term with its description:

    <p>α-helix = A right-handed helical structure with hydrogen bonds β-sheet = A pleated sheet structure formed by lateral hydrogen bonds Hydrophobic interactions = Interactions primarily determining tertiary structure R groups = Side chains of amino acids affecting protein structure</p> Signup and view all the answers

    Which type of β-sheet configuration provides the strongest inter-strand stability?

    <p>Anti-parallel (A)</p> Signup and view all the answers

    The tertiary structure of proteins is primarily determined by the sequence of amino acids.

    <p>False (B)</p> Signup and view all the answers

    What type of bonding connects β-strands in a β-sheet?

    <p>Hydrogen bonds</p> Signup and view all the answers

    Study Notes

    Metals in Biochemistry/Biology

    • Amino acids are the building blocks of proteins.
    • See separate documents on Canvas for more details on amino acids and protein structures
    • The Henderson-Hasselbalch equation helps predict the predominant form of an acid at a given pH.
    • Acids have a pKa value, it is fundamental to the acid.
    • pH is what can be adjusted
    • pKa = pH + log [HA]/[A-]
    • If pH < pKa, then [HA] > [A-], and the protonated form (HA) will be present.
    • If pH > pKa, then [HA] < [A-], and the deprotonated form (A-) will be present.

    Amino Acids

    • There are twenty common amino acids.
    • Each amino acid has a unique structure and properties.
    • Amino acids are grouped by their properties.
    • Examples of amino acids include Alanine, Arginine, Asparagine, etc.
    • pKa values for the side chain groups of amino acids are often given in parentheses.

    Protein Structures

    • Proteins are made of amino acids connected by peptide bonds.
    • The primary structure is the sequence of amino acids.
    • The secondary structure describes the local folding of the polypeptide chain like α-helices and β-sheets.
    • The tertiary structure is the overall 3D folding pattern of the entire polypeptide chain, determined by interactions between the R groups of the amino acids.
    • The quaternary structure arises when multiple polypeptide chains assemble to form a larger functional unit.
    • Examples include; Hemoglobin.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Metals in Biochemistry Notes PDF

    Description

    This quiz explores essential concepts of metals in biochemistry, focusing on amino acids, their structures, and the significance of pH in relation to pKa values. Understand how these factors influence the form of acids and the properties of amino acids. Test your knowledge on the building blocks of proteins and their functional roles.

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser