Metal Ions in Catalysis
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Questions and Answers

What is the role of metal ions in enzyme catalysis for orientation of substrates?

  • Shielding positive charges
  • Electrostatically stabilizing negative charges
  • Activating the enzyme
  • Mediating oxidation-reduction reactions (correct)
  • What is the function of a coenzyme in enzyme catalysis?

  • Stabilize the enzyme's active site
  • Directly participate in the reaction mechanism (correct)
  • Assist in substrate binding
  • Provide structural stability to the enzyme
  • Which term describes an enzyme without its bound cofactor?

  • Coenzyme
  • Holoenzyme
  • Cofactorase
  • Apoenzyme (correct)
  • In enzyme catalysis, how do metal ions act similarly to H+?

    <p>By stabilizing negative charges</p> Signup and view all the answers

    What is the term for enzymes that require a metal ion cofactor for activity?

    <p>Metaloenzymes</p> Signup and view all the answers

    How do enzymes exhibit specificity towards substrates?

    <p>Through charge complementarity</p> Signup and view all the answers

    What did Daniel Koshland modify in the 'lock and key' model of enzyme-substrate interaction?

    <p>The amino acid side chains making up the active site</p> Signup and view all the answers

    Which model explains both enzyme specificity and the stabilization of the transition state?

    <p>Induced fit model</p> Signup and view all the answers

    In chiral reactions, enzymes are typically:

    <p>Stereospecific</p> Signup and view all the answers

    What concept from transition state theory helps explain how enzymes catalyze chemical reactions?

    <p>Reaction Coordinate</p> Signup and view all the answers

    Which statement is true regarding metal ion cofactors in enzymes?

    <p>They can alter the shape of the active site</p> Signup and view all the answers

    What role do coenzymes play in enzyme-catalyzed reactions?

    <p>Facilitate electron transfer reactions</p> Signup and view all the answers

    What region of an enzyme contains the catalytic residues and binds the substrate to carry out the reaction?

    <p>Active site</p> Signup and view all the answers

    Which type of molecules can act as cofactors for enzymes?

    <p>Metal ions and organic molecules</p> Signup and view all the answers

    What is the role of coenzymes in enzymatic reactions?

    <p>To transiently associate with enzymes</p> Signup and view all the answers

    Which type of enzymes require metal ions for their catalytic activity?

    <p>Metalloenzymes</p> Signup and view all the answers

    What is the function of metal ion cofactors in metalloenzymes?

    <p>Act as essential components for catalysis</p> Signup and view all the answers

    Which type of cofactors are most commonly associated with vitamins?

    <p>Coenzymes</p> Signup and view all the answers

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