Podcast
Questions and Answers
What is the main function of liver glycogen?
What is the main function of liver glycogen?
- To maintain the blood glucose concentration in the fasting state (correct)
- To synthesize glycogen storage diseases
- To provide a readily available source of glucose-1-phosphate for glycolysis within the muscle itself
- To convert glucose-6-phosphatase into pyruvate
Where does glycogen occur mainly in the body?
Where does glycogen occur mainly in the body?
- Liver and muscle (correct)
- Heart and lungs
- Muscle and brain
- Brain and liver
What is the approximate concentration of glycogen in the liver after a meal?
What is the approximate concentration of glycogen in the liver after a meal?
- 450 mmol /L glucose equivalents (correct)
- 100 mmol /L glucose equivalents
- 200 mmol /L glucose equivalents
- 550 mmol /L glucose equivalents
What is the fate of pyruvate formed by glycolysis in muscle?
What is the fate of pyruvate formed by glycolysis in muscle?
What percentage of total body glycogen is in muscle?
What percentage of total body glycogen is in muscle?
What happens to liver glycogen after 12 to 18 hours of fasting?
What happens to liver glycogen after 12 to 18 hours of fasting?
What is the result of phosphorylation of glycogen phosphorylase?
What is the result of phosphorylation of glycogen phosphorylase?
What is the fate of cAMP in the presence of phosphodiesterase?
What is the fate of cAMP in the presence of phosphodiesterase?
What is the role of glycogen in the liver?
What is the role of glycogen in the liver?
What is the effect of insulin on phosphodiesterase in the liver?
What is the effect of insulin on phosphodiesterase in the liver?
What is the enzyme that catalyzes the phosphorylation of glycogen phosphorylase?
What is the enzyme that catalyzes the phosphorylation of glycogen phosphorylase?
What is the source of glucose-6-phosphate for glycolysis in muscle?
What is the source of glucose-6-phosphate for glycolysis in muscle?
Where does glycogenin stay associated and form the core of?
Where does glycogenin stay associated and form the core of?
During glycogen elongation, what type of bond is formed between the glucose of UDPGlc and a terminal glucose residue of glycogen?
During glycogen elongation, what type of bond is formed between the glucose of UDPGlc and a terminal glucose residue of glycogen?
At what point does branching of glycogen occur?
At what point does branching of glycogen occur?
What type of linkages are formed in the branching of glycogen?
What type of linkages are formed in the branching of glycogen?
What is the effect of insulin on cAMP levels?
What is the effect of insulin on cAMP levels?
What is active in heart muscle but not in skeletal muscle?
What is active in heart muscle but not in skeletal muscle?
What is the allosteric activator of the dephosphorylated b-form of phosphorylase in muscle?
What is the allosteric activator of the dephosphorylated b-form of phosphorylase in muscle?
What is the signal that triggers increased cAMP formation in the liver?
What is the signal that triggers increased cAMP formation in the liver?
What is the outcome of the reaction catalyzed by adenylate kinase?
What is the outcome of the reaction catalyzed by adenylate kinase?
Which of the following inhibits active phosphorylase A in the liver?
Which of the following inhibits active phosphorylase A in the liver?
What is the response of the muscle cell to increasing ADP concentration?
What is the response of the muscle cell to increasing ADP concentration?
What is the outcome of phosphorylase kinase a phosphorylating phosphorylase b?
What is the outcome of phosphorylase kinase a phosphorylating phosphorylase b?
What is the primary function of the sequence of reactions in glycogenolysis?
What is the primary function of the sequence of reactions in glycogenolysis?
What triggers the initiation of both muscle contraction and glycogenolysis?
What triggers the initiation of both muscle contraction and glycogenolysis?
What is the function of the δ subunit of muscle phosphorylase kinase?
What is the function of the δ subunit of muscle phosphorylase kinase?
In the liver, what is the response to stimulation of α1 adrenergic receptors by epinephrine and norepinephrine?
In the liver, what is the response to stimulation of α1 adrenergic receptors by epinephrine and norepinephrine?
What is the effect of phosphorylation on the γ subunit of muscle phosphorylase kinase?
What is the effect of phosphorylation on the γ subunit of muscle phosphorylase kinase?
What is the role of Ca2+ in the activation of muscle phosphorylase?
What is the role of Ca2+ in the activation of muscle phosphorylase?
