Lecture 5

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Questions and Answers

What is the main reason why the same input to a muscle (twitch) results in significantly more force output in the potentiated state?

  • Decreased twitch potentiation
  • Changes in Ca2+ kinetics at the sarcoplasmic reticulum level (correct)
  • Myosin light-chain dephosphorylation during actin/myosin interaction
  • Reduction in motor unit firing rates

How are motor unit firing rates affected by potentiation?

  • Motor unit firing rates decrease significantly
  • Motor unit firing rates increase significantly (correct)
  • Motor unit firing rates become irregular
  • Motor unit firing rates remain unchanged

What is the main factor that enhances the active state during a brief high-intensity tetanus or voluntary contractions?

  • Enhanced neural input to the system
  • Decrease in twitch potentiation
  • Increase in Ca2+ concentration at the myofilaments (correct)
  • Reduction in myosin light-chain phosphorylation

Which of the following statements best describes the effects of muscle potentiation on force production?

<p>Potentiation allows greater forces to be achieved with less neural input (C)</p> Signup and view all the answers

What are the two likely mechanisms responsible for muscle potentiation during high-intensity contractions?

<p>Ca2+ kinetics at the SR level and myosin light-chain phosphorylation (C)</p> Signup and view all the answers

What limits the ability to continually flex a finger under a fixed load according to the text?

<p>Central nervous system fatigue (A)</p> Signup and view all the answers

What is one of the factors affected by metabolic perturbations that can lead to reduced force output?

<p>Reduced force/cross-bridge (B)</p> Signup and view all the answers

What is the big controversy mentioned in the text related to when discussing metabolites and their impact on the fatigue response?

<p>The relative contributions of metabolites (C)</p> Signup and view all the answers

Why is it mentioned that finger flexion can still occur with electrical stimulation despite limitations within central systems?

<p>To illustrate the impact of muscle fatigue on voluntary activation (D)</p> Signup and view all the answers

What does an increasing superimposed twitch throughout a fatiguing task indicate?

<p>Motor units not recruited (B)</p> Signup and view all the answers

Which factor contributes to decreased muscle activation (reduced firing rates) with fatigue according to the text?

<p>Increased inhibition (A)</p> Signup and view all the answers

Is it favorable or unfavorable when firing rates decline as muscle contractile speed slows down?

<p>Unfavorable, as it may result in decreased force output (D)</p> Signup and view all the answers

What is the main reason for reduced ROM due to fatigue in the text?

<p>task specificity (C)</p> Signup and view all the answers

Which factor contributes to the inability to generate an initial force appropriate for a task in the text?

<p>Weakness (B)</p> Signup and view all the answers

What is the primary reason why fatigue processes are not sustainable indefinitely according to the text?

<p>Compensatory mechanisms (B)</p> Signup and view all the answers

What contributes significantly to the reduction in muscle response force and contractile speed during maximal or high intensity exercise?

<p>Metabolic substrates availability (D)</p> Signup and view all the answers

What is the relationship between firing rates and muscle speed according to the text?

<p>Firing rates decrease with slowed muscle speed. (C)</p> Signup and view all the answers

What mechanism may lead to a loss of force during sustained maximal contractions?

<p>Decreased motor unit firing rates (B)</p> Signup and view all the answers

In sub-maximal tasks, what combination plays a role in generating force?

<p>Recruitment and rate coding (C)</p> Signup and view all the answers

What is one cause for loss of force during sustained maximal exercise according to the text?

<p>Reduced sensitivity and release of Ca+2 (A)</p> Signup and view all the answers

What is the effect of task specificity on force generation during submaximal intermittent exercise?

<p>Decreased motor unit firing rates (C)</p> Signup and view all the answers

During maximal sustained exercise, what happens to EMG activity?

<p>It increases until the contraction becomes maximal. (C)</p> Signup and view all the answers

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