Menopause Pharmacotherapy
30 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the definition of menopause?

  • The first year after menopause
  • The period immediately prior to the cessation of menses
  • The time after menopause has occurred, starting when a woman has not had a period for 6 consecutive months
  • The permanent cessation of menses following the loss of ovarian follicular activity (correct)

What is the definition of postmenopause?

  • The first year after menopause
  • The time after menopause has occurred, starting when a woman has not had a period for 12 consecutive months (correct)
  • The permanent cessation of menses following the loss of ovarian follicular activity
  • The period immediately prior to the menopause and the first year after menopause

What is the definition of perimenopause?

  • The period immediately prior to the menopause and the first year after menopause (correct)
  • The permanent cessation of menses following the loss of ovarian follicular activity
  • The time after menopause has occurred, starting when a woman has not had a period for 12 consecutive months
  • The first year after menopause

What is the number of consecutive months without a period required to define postmenopause?

<p>12 (D)</p> Signup and view all the answers

What is the title of the chapter in Pharmacotherapy: a pathophysiologic approach that discusses hormone therapy in women?

<p>Chapter 31 (C)</p> Signup and view all the answers

What is the name of the organization that provides guidelines for the diagnosis and management of menopause?

<p>NICE (C)</p> Signup and view all the answers

What is the recommended first-line therapy for patients without VMS?

<p>Topical vaginal preparations (C)</p> Signup and view all the answers

Why may women using high doses of topical estrogen products require intermittent treatment?

<p>To supplement with a progestogen (B)</p> Signup and view all the answers

What is the benefit of using estradiol in the form of a vaginal tablet or ring?

<p>It is not significantly absorbed systemically (A)</p> Signup and view all the answers

What is the condition that affects millions of women and is associated with a high incidence of morbidity and mortality and decreased QOL?

<p>Postmenopausal osteoporosis (B)</p> Signup and view all the answers

What was the first RCT to demonstrate a reduction in total fractures?

<p>WHI study (C)</p> Signup and view all the answers

What was the only vaginal ring indicated for VMS?

<p>Femring (C)</p> Signup and view all the answers

Which hormone stimulates the anterior pituitary to secrete FSH and LH?

<p>Gonadotropin releasing hormone (GnRH) (A)</p> Signup and view all the answers

What happens to FSH levels during menopause?

<p>They increase 10-15 fold (B)</p> Signup and view all the answers

What is the primary goal of menopause treatment?

<p>To improve quality of life while minimizing adverse effects (B)</p> Signup and view all the answers

What is a long-term symptom of menopause?

<p>Osteoporosis (A)</p> Signup and view all the answers

What is the diagnostic criterion for menopause?

<p>FSH levels &gt; 40 mIU/mL (IU/L) for 1 year (A)</p> Signup and view all the answers

What is the most effective treatment for vasomotor symptoms and vulvovaginal atrophy?

<p>Hormone replacement therapy (HRT) (B)</p> Signup and view all the answers

What should women do when considering therapies for menopause?

<p>Assess the benefits and risks of all therapies and discuss these options with their health care providers (B)</p> Signup and view all the answers

What is the mechanism of action of SERMs in different tissues?

<p>They act as estrogen agonists and antagonists, depending on the target tissue (B)</p> Signup and view all the answers

What is the benefit of SERMs in terms of bone health?

<p>They prevent bone loss and vertebral fractures (B)</p> Signup and view all the answers

What is the approved indication for ospemifene (Osphena) 60mg PO?

<p>Treatment of moderate to severe dyspareunia associated with vulvovaginal atrophy (A)</p> Signup and view all the answers

What is the first-line therapy for the relief of moderate to severe VMS and vulvovaginal atrophy?

<p>Estrogen +/– progestogen (C)</p> Signup and view all the answers

What is recommended for women with a uterus taking ospemifene?

<p>Adding a progestin to ospemifene (A)</p> Signup and view all the answers

What should be explained to women who are stopping HRT?

<p>Gradually reducing HRT may limit recurrence of symptoms in the short term. (C)</p> Signup and view all the answers

What is the recommended frequency for reassessing women for symptoms after stopping HRT?

<p>Every 6-12 months (A)</p> Signup and view all the answers

What should be checked in a patient taking HT who remains symptomatic?

<p>Poor absorption, drug interactions, patch adhesion, and incorrect diagnosis (C)</p> Signup and view all the answers

Why may the dose of oestrogen in HRT need to be adjusted?

<p>Because the dose may be too low (D)</p> Signup and view all the answers

What should be encouraged in women taking HRT?

<p>Breast awareness and participation in screening mammography (D)</p> Signup and view all the answers

What should be monitored in a patient taking HRT?

<p>Side-effects, blood pressure, weight, and breast awareness (D)</p> Signup and view all the answers

More Like This

Hormone Therapy for Menopause
30 questions
Hormone Therapy and Menopause
38 questions
Menopausia
77 questions

Menopausia

RestfulPraseodymium avatar
RestfulPraseodymium
Use Quizgecko on...
Browser
Browser