24 Questions
What is the probability that their fourth child will be born with phenylketonuria if the parents are carriers?
25 %
What is the genotype of the blue-eyed father?
aa
What is the probability that a child will inherit Marfan's disease if one parent has the disease and the other is unaffected?
50 %
What is the genetic phenomenon that causes the development of symptoms of Marfan's disease?
pleiotropy
What is the genetic phenomenon that causes the development of symptoms of Hartnep's disease?
point mutation
What is the genotype of the brown-eyed mother?
Aa
What is the probability that a child will inherit phenylketonuria if both parents are carriers?
25 %
What is the genotype of the parents if a blue-eyed father and a brown-eyed mother have 5 children, including 2 blue-eyed children?
aa x Aa
When inheriting a trait, which law applies?
Independent inheritance
What is the probability of the woman having a deaf child if her husband is homozygous for the normal hearing allele?
0%
What law of inheritance will manifest in the children of the husband and wife with a wide gap between the incisors?
Uniformity of first-generation hybrids
What is the probability of having a child with phenylketonuria in the family where one healthy spouse is suspected to have a recessive phenylketonuria gene?
25%
What can be inferred about the genotype of the healthy daughter in the family with two sons with phenylketonuria?
She is heterozygous for the recessive gene
What is the genotype of the husband in the family with a deaf and dumb couple, where the wife's deafness is due to an autosomal recessive gene?
Homozygous for the normal gene
What is the probability of the couple having a child with a wide gap between the incisors, given that both parents are homozygous for the dominant trait?
100%
What is the relationship between the genotype of the parents and the phenotype of their children in the case of phenylketonuria?
Autosomal recessive inheritance
What is the probability of a boy having hemophilia-A in a family where the child's mother and her parents did not suffer from this disease, and the child's father has been ill since birth?
50% of boys will be sick
If a woman's husband has hemophilia-B, what is the risk of having a sick child for the couple?
0%
What is the probability of color blindness in children of a man with color blindness if the genotype of his wife does not contain this allele?
0%
If the wife's father is ill with hemophilia-A, what is the probability of their sons being affected?
50%
If a woman's father has hemophilia-A, what is the probability of her sons being affected?
50%
What is the probability of a child being a carrier of hemophilia-A if the mother is a carrier and the father is normal?
50%
If a woman's husband has hemophilia-B, what is the probability of their daughters being carriers?
50%
What is the probability of color blindness in daughters of a man with color blindness if the genotype of his wife does not contain this allele?
50%
Study Notes
Laws of Inheritance
- When inheriting a trait, the law of inheritance that applies is uniformity of first-generation hybrids.
- This means that the first-generation hybrids will have a uniform trait, in this case, the gap between the incisors.
Inheritance of Traits
- A couple with a wide gap between their incisors (a dominant feature) will have children with the same trait because they are both homozygous.
- The law of inheritance that applies in this case is uniformity of first-generation hybrids.
Probability of Inheritance
- If a woman's deafness is due to an autosomal recessive gene and her husband is homozygous for the normal hearing allele, the probability of having a deaf child is 0%.
- If one healthy spouse is suspected to have a recessive phenylketonuria gene, the probability of having a child with phenylketonuria is 25%.
- If healthy parents have two sons with phenylketonuria and one healthy daughter, the probability that their fourth child will be born with phenylketonuria is 25%.
Genotypes and Phenotypes
- A blue-eyed father and a brown-eyed mother can have 5 children, including 2 blue-eyed children, if the genotypes of the parents are Aa x aa.
- A boy with Marfan's disease suffers from a violation of the development of connective tissue, changes in the structure of the lens of the eye, and abnormalities of the cardiovascular system, which is caused by the genetic phenomenon of pleiotropy.
Genetic Phenomena
- A point mutation of one gene causes the development of Hartnep's disease, which is an example of pleiotropy.
- The development of symptoms of Hartnep's disease is caused by the genetic phenomenon of pleiotropy.
Probability of Inheritance (continued)
- If the child's mother and her parents did not suffer from hemophilia-A, and the child's father has been ill since birth, the probability of having a boy with hemophilia-A is 50%.
- If the woman's husband suffers from hemophilia-B and there were no cases of hemophilia in the woman's family, the risk of having a sick child for the couple is 25%.
- If a man with color blindness has a wife with a genotype that does not contain the allele, the probability of color blindness in their children is 0%.
Inheritance of Hemophilia
- The following people may develop hemophilia: half of the sons.
- If the couple is healthy, but the wife's father is ill with hemophilia-A, the probability of having a child with hemophilia-A is 50%.
This quiz questions the application of a fundamental law of inheritance in a specific scenario. The law describes how genetic traits are passed down from parents to offspring. In this case, the trait in question is a wide gap between the incisors.
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