Mendel's Genetics Experiments
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Questions and Answers

What does Mendel refer to as a heritable feature that differs among individuals?

  • Character (correct)
  • Trait
  • Generation
  • Hybrid

What is the name of the process Mendel used to produce hybrid offspring?

  • Hybridization (correct)
  • Segregation
  • Self-fertilization
  • Cross-pollination

Which generation is produced from the cross of two true-breeding varieties?

  • F2 generation
  • P generation
  • Hybrid generation
  • F1 generation (correct)

What happened when Mendel cross-pollinated white flowered and purple flowered pea plants?

<p>All F1 hybrids had purple flowers (C)</p> Signup and view all the answers

Which of the following principles of heredity did Mendel deduce from his experiments?

<p>Law of Segregation (C)</p> Signup and view all the answers

Why did Mendel choose pea plants for his experiments?

<p>They have many varieties and can be easily controlled (C)</p> Signup and view all the answers

What was the result of Mendel's expectation if blending model of inheritance were true?

<p>F1 hybrids would have pale purple flowers (A)</p> Signup and view all the answers

What character did Mendel track in his pea plant experiments?

<p>Flower color (D)</p> Signup and view all the answers

What determines the ABO blood groups in humans?

<p>Three possible alleles: Iᴬ, Iᴮ, and i (D)</p> Signup and view all the answers

Which of the following best describes pleiotropy?

<p>One gene influencing multiple traits (C)</p> Signup and view all the answers

What is the phenotypic outcome when two heterozygous individuals are crossed in a polygenic trait like skin color?

<p>Offspring will have a range of skin tones (D)</p> Signup and view all the answers

Which statement correctly describes epistasis?

<p>It occurs when one gene masks the effect of another gene (B)</p> Signup and view all the answers

How many genetic variations influence human height?

<p>More than 700 genetic variations (C)</p> Signup and view all the answers

Which of the following traits is an example of polygenic inheritance?

<p>Skin color in humans (B)</p> Signup and view all the answers

What does the term 'multifactorial' refer to in genetics?

<p>Influence of both genetic and environmental factors on phenotype (D)</p> Signup and view all the answers

What characterizes a phenotype?

<p>All aspects of an organism's appearance, anatomy, and behavior (B)</p> Signup and view all the answers

What type of genetic relationship does polygenic inheritance represent?

<p>Multiple genes contributing additively to a trait (D)</p> Signup and view all the answers

Which statement regarding environmental factors in multifactorial characters is true?

<p>They contribute to the variation of phenotypes (A)</p> Signup and view all the answers

What is the purpose of a testcross?

<p>To determine the unknown genotype of an individual (D)</p> Signup and view all the answers

What type of offspring results from a cross between two true-breeding plants with different traits for a single character?

<p>Monohybrids (A)</p> Signup and view all the answers

What are the expected phenotypic ratios resulting from a dihybrid cross under the Law of Independent Assortment?

<p>9:3:3:1 (D)</p> Signup and view all the answers

Which hypothesis predicts the alleles for different characters assort together during gamete formation?

<p>Dependent assortment (A)</p> Signup and view all the answers

In Mendel's experiments, which generation was produced by self-pollinating dihybrid F1 plants?

<p>F2 generation (D)</p> Signup and view all the answers

What does the multiplication rule in genetics help determine?

<p>Probability of multiple independent events occurring (B)</p> Signup and view all the answers

What genotype would result from a testcross involving a heterozygous individual?

<p>Any combination of dominant and recessive (B)</p> Signup and view all the answers

What would Mendel's testcross reveal about the genotype of a plant with purple flowers?

<p>The genotype could be homozygous or heterozygous (D)</p> Signup and view all the answers

Which statement reflects Mendel's Law of Independent Assortment?

<p>Different traits segregate independently of each other. (A)</p> Signup and view all the answers

Which gametes can a plant with genotype YyRr produce under independent assortment?

<p>YR, Yr, yR, and yr (A)</p> Signup and view all the answers

What would be the outcome if alleles assort dependently?

<p>A 3:1 phenotypic ratio (D)</p> Signup and view all the answers

Why do plants with genotype YyRr exhibit dominant traits?

<p>One dominant allele per trait is sufficient (A)</p> Signup and view all the answers

In Mendel's dihybrid crosses, what pattern did he observe among the phenotypic ratios?

<p>Consistantly close to 9:3:3:1 ratio (A)</p> Signup and view all the answers

What is the primary evidence that the white-flower trait reappears in the F2 generation?

<p>The heritable factor for white flowers had not been destroyed. (C)</p> Signup and view all the answers

What are alleles in the context of Mendel's experiments?

<p>Alternative versions of a gene. (B)</p> Signup and view all the answers

According to Mendel's Law of Segregation, what occurs during gamete formation?

<p>Alleles segregate into different gametes. (B)</p> Signup and view all the answers

In Mendel's F1 hybrids, which genotype would result in a purple flower trait?

<p>Both homozygous dominant (PP) and heterozygous (Pp). (A)</p> Signup and view all the answers

What is a testcross used for in genetics?

<p>To identify the genotype of a plant with a dominant phenotype. (D)</p> Signup and view all the answers

What type of genotype is represented by a plant that is homozygous for a trait?

<p>Has two identical alleles. (A)</p> Signup and view all the answers

What was the approximate phenotypic ratio of purple to white flowers in Mendel's F2 generation?

<p>3:1 (D)</p> Signup and view all the answers

Which of the following best describes a heterozygote?

<p>An organism with two different alleles for a gene. (D)</p> Signup and view all the answers

In Mendel's experiments, which statement is true about the F1 generation?

<p>Purple flower trait masked the white flower trait. (D)</p> Signup and view all the answers

What role do chromosomes play in Mendel's model of inheritance?

<p>They carry the alleles and account for trait variation. (B)</p> Signup and view all the answers

What happens if a pink flower trait was observed alongside purple and white flowers in offspring?

<p>It indicates incomplete dominance. (D)</p> Signup and view all the answers

Which statement accurately reflects Mendel’s view of dominant and recessive traits?

<p>Dominant traits mask the expression of recessive traits. (A)</p> Signup and view all the answers

Which of the following concepts did Mendel not consider when developing his model?

<p>The presence of chromosomes. (C)</p> Signup and view all the answers

If a homozygous dominant plant (PP) is crossed with a heterozygous plant (Pp), what is the expected phenotypic ratio of their offspring?

<p>1:0 (B)</p> Signup and view all the answers

What is the overall probability of obtaining an Rr heterozygote from a monohybrid cross?

<p>$1/2$ (A)</p> Signup and view all the answers

Which rule is used to calculate the probability of multiple independent genetic events, like obtaining genotypes from a dihybrid cross?

<p>Multiplication rule (A)</p> Signup and view all the answers

How can at least two recessive phenotypes be expected in offspring from a cross involving three characters?

<p>By combining both multiplication and addition rules (A)</p> Signup and view all the answers

What is the expected phenotype ratio for the recessive trait of seed color (yy) from a cross between Yy and yy parents?

<p>1/2 (D)</p> Signup and view all the answers

How does incomplete dominance differ from complete dominance in genetic expression?

<p>In incomplete dominance, offspring show a blend of parental traits (D)</p> Signup and view all the answers

Which scenario exemplifies codominance?

<p>Human blood groups expressed with both M and N antigens (A)</p> Signup and view all the answers

How many different combinations of recessive traits can appear from the PpYyRr x Ppyyrr cross?

<p>Four (B)</p> Signup and view all the answers

In Mendel's pea plants, what is the main reason that the F1 hybrids appear indistinguishable from the dominant homozygotes?

<p>One allele is completely dominant (A)</p> Signup and view all the answers

What probability is assigned to a dominant homozygote offspring phenotype resulting from a monohybrid cross?

<p>$3/4$ (D)</p> Signup and view all the answers

What outcome occurs when a recessive allele and a dominant allele coexist in a heterozygote?

<p>Dominance affects the phenotype without interaction (A)</p> Signup and view all the answers

In calculating the probabilities for multiple traits, what mathematical operation is indicated by the term 'and'?

<p>Multiplication rule (C)</p> Signup and view all the answers

From the PpYyRr x Ppyyrr cross, what fraction of offspring is expected to exhibit the dominant phenotypes for all three traits?

<p>1/8 (B)</p> Signup and view all the answers

Which of the following statements about Mendelian classifications of dominance is true?

<p>The term ‘dominant’ refers to the visibility of the allele's trait (D)</p> Signup and view all the answers

For a single gene with two alleles, what term describes when both alleles contribute equally to the phenotype in heterozygotes?

<p>Codominance (C)</p> Signup and view all the answers

Flashcards

Mendel's experimental approach

Mendel used controlled matings of pea plants to study patterns of inheritance.

Character

Heritable feature differing among individuals; Ex: flower color.

Trait

Variants of a character; Ex: purple or white flower color.

Cross-pollination

Transferring pollen from one plant to another, ensuring known parentage of offspring.

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P generation

Parent generation in genetic crosses.

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F1 generation

First filial generation in genetic crosses, offspring of P generation.

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Law of Segregation

Offspring inherit one allele for each gene from each parent during gamete formation.

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Hybrid offspring

Offspring of crosses between different varieties or species.

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Dominant allele

An allele that determines the organism's appearance when two different alleles are present.

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Recessive allele

An allele that has no noticeable effect on the organism's appearance when a dominant allele is present.

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Allele

Alternative versions of a gene that account for variations in inherited characters.

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Homozygote

An organism with a pair of identical alleles for a gene.

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Heterozygote

An organism with two different alleles for a gene.

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Phenotype

An organism's observable traits, including physical and physiological characteristics, like purple flowers.

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Genotype

An organism's genetic makeup, comprising its alleles.

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Testcross

A mating between an individual of unknown genotype and a homozygous recessive individual to determine the unknown genotype.

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True-breeding

Organisms that, when self-pollinated, produce offspring with the same trait as the parent.

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3:1 ratio

The expected phenotypic ratio of dominant to recessive traits in the F2 generation of a monohybrid cross.

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Monohybrid cross

A cross (mating) between organisms that are heterozygous for one paired gene.

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Locus

A specific position on a chromosome where a gene is located.

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Diploid

Having two sets of chromosomes.

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What is a dihybrid cross?

A cross between two individuals that are heterozygous for two different traits.

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Independent Assortment

During gamete formation, alleles for different traits segregate independently of each other, meaning each gamete receives a random combination of alleles.

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Phenotypic ratio

The ratio of different phenotypes observed in the offspring of a cross.

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What is the phenotypic ratio of a dihybrid cross?

A typical dihybrid cross results in a 9:3:3:1 phenotypic ratio in the offspring.

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Multiplication rule

The probability of two events happening together is the product of the probabilities of each individual event.

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What is the difference between dependent and independent assortment?

Dependent assortment implies alleles are inherited together in the same combinations as received from the parent generation, while independent assortment allows alleles to be randomly distributed into gametes.

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What does a 3:1 phenotypic ratio indicate?

A 3:1 phenotypic ratio suggests that the alleles for the trait segregate according to Mendel's Law of Segregation, indicating a monohybrid cross.

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What are the possible gametes produced by a YyRr plant?

A YyRr plant can produce four types of gametes in equal amounts: YR, Yr, yR, and yr.

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What does the 9:3:3:1 phenotypic ratio of a dihybrid cross demonstrate?

This ratio supports Mendel's Law of Independent Assortment, indicating that the genes for seed color and shape are independently inherited.

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How does the Law of Independent Assortment apply to chromosomes?

The Law of Independent Assortment applies to genes located on different chromosomes or very far apart on the same chromosome.

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What are the key observations from Mendel's dihybrid cross experiments?

Mendel consistently observed a 9:3:3:1 phenotypic ratio in the offspring of dihybrid crosses, supporting the Law of Independent Assortment.

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How can we apply the multiplication rule to monohybrid crosses?

We can use the multiplication rule to calculate the probability of specific combinations of alleles in the offspring of a monohybrid cross.

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Addition Rule

The probability of either of two mutually exclusive events occurring is the sum of their individual probabilities.

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Dihybrid cross

A cross between individuals that are heterozygous for two different genes.

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Incomplete Dominance

A heterozygote has a phenotype that is intermediate between the phenotypes of the two homozygotes.

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Codominance

Both alleles are expressed fully in the heterozygote, resulting in a phenotype that shows both traits equally.

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Recessive phenotype

The phenotype observed in an individual with two recessive alleles.

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Dominant phenotype

The phenotype expressed in an individual with at least one copy of the dominant allele.

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Probability of Recessive Phenotypes

The likelihood of offspring exhibiting a recessive trait depends on the specific alleles inherited from their parents.

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What is the key difference between incomplete dominance and codominance?

In incomplete dominance, the heterozygote displays a phenotype that is a blend of the two homozygous phenotypes, while in codominance, both alleles are fully expressed, resulting in a phenotype that shows both traits equally.

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Why is an allele considered 'dominant'?

An allele is called dominant because it is seen in the phenotype, not because it subdues a recessive allele. It is the pathway from genotype to phenotype that determines dominance.

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How does the defective enzyme in the wrinkled pea seed allele affect phenotype?

The defective enzyme produced by the recessive allele for wrinkled seeds causes unbranched starch to accumulate in the seed, leading to excess water absorption and wrinkling when the seed dries.

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Explain why a heterozygous individual with a dominant allele doesn't necessarily express the recessive trait.

A single copy of the dominant allele provides enough functional enzyme to produce the dominant phenotype, effectively masking the expression of the recessive allele.

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Can you predict the genotypic ratio of an F2 generation from a dihybrid cross?

Yes, using the rules of probability, you can calculate the expected genotypic ratio of an F2 generation from a dihybrid cross, taking into account the independent assortment of alleles for each gene.

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Multiple Alleles

A gene with more than two possible alleles, resulting in various phenotypes.

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Pleiotropy

One gene influencing multiple phenotypic traits.

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Epistasis

One gene's expression affecting another gene's expression.

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Quantitative Characters

Traits showing continuous variation across a spectrum.

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Polygenic Inheritance

Multiple genes contributing additively to a single trait.

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Multifactorial

Traits influenced by both genetic and environmental factors.

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Blood Transfusion

Transferring blood from one person to another, requiring careful matching of blood groups.

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Study Notes

Mendel's Experimental Approach

  • Mendel likely chose pea plants due to their availability in various traits (e.g., purple or white flowers).
  • A character is a heritable feature that varies among individuals, and a trait is a specific variant of that feature.
  • Pea flowers allow for self-fertilization or controlled cross-pollination by removing stamens and transferring pollen.
  • Mendel tracked traits across generations (P, F1, F2) using large sample sizes and precise records.
  • He focused on characters with distinct, alternative forms.

The Law of Segregation

  • If inheritance were blending, F1 offspring would show an intermediate trait, but all F1 offspring had the same color (purple) as one parent.
  • Mendel's data showed a 3:1 ratio of purple to white flowers in the F2 generation, demonstrating that traits, not diluted, were passed on.
  • Purple is the dominant trait, white is recessive—the recessive trait reappeared in the F2 generation.
  • Mendel's model explains the 3:1 pattern:
    • Alternate versions of genes (alleles) cause variations in a character.
    • Each organism has two alleles for each character—one from each parent (diploid).
    • If alleles differ, the dominant allele determines the appearance, and the recessive has no effect.
    • Alleles segregate during gamete formation. This relates to the distribution of chromosomes in meiosis.

Useful Genetic Vocabulary

  • Homozygote: organism with identical alleles for a gene (e.g., PP or pp)
  • Heterozygote: organism with different alleles for a gene (e.g., Pp)
  • Genotype: genetic makeup
  • Phenotype: observable traits

The Testcross

  • Used to determine an unknown genotype of an organism showing a dominant trait.
  • Involves crossing the unknown with a homozygous recessive individual.

The Law of Independent Assortment

  • Mendel extended his studies to two characters simultaneously, like seed color and shape.
  • Dihybrid crosses (YyRr x YyRr) revealed that alleles for different genes segregate independently into gametes.
  • Independent assortment results in a 9:3:3:1 phenotypic ratio in the F2 generation. This differs from a 3:1 ratio in monohybrid crosses.

Probability and Mendelian Inheritance

  • The multiplication rule determines the probability of independent events occurring together (e.g., two heads from two coin flips = 1/4).
  • The addition rule determines the probability of any one of multiple mutually exclusive events occurring.
  • These rules are applied to solve more complex crosses.

Extending Mendelian Genetics

  • Degrees of Dominance:

    • Complete dominance: one allele fully masks the other (Mendel's peas).
    • Incomplete dominance: heterozygotes have an intermediate phenotype (e.g., pink snapdragons).
    • Codominance: both alleles are fully expressed in heterozygotes (e.g., MN blood groups)
  • Multiple alleles: more than two alleles for a gene exist (e.g., ABO blood groups)

  • Pleiotropy: one gene influences multiple traits (e.g., sickle cell disease).

  • Epistasis: one gene affects the expression of another.

  • Polygenic inheritance: multiple genes additively influence a trait (e.g., human skin color)

Environmental Impact

  • Environment often influences the phenotype of polygenic traits (multifactorial inheritance).
  • Genotype does not fully determine the phenotype; environment plays a role.

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Description

Explore Mendel's revolutionary experiments with pea plants that led to foundational principles in genetics. This quiz covers his experimental approach, the concept of inheritance, and the Law of Segregation. Test your knowledge on the characteristics and traits Mendel meticulously tracked across generations.

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