Mendelian Inheritance and Chromosomes

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Questions and Answers

What is the term for different forms of the same gene?

  • Phenotype
  • Locus
  • Genotype
  • Alleles (correct)

A trait determined by a single gene is referred to as:

  • Discrete
  • Polygenic
  • Continuous
  • Monogenic (correct)

Which process of cell division results in gametes?

  • Meiosis (correct)
  • Replication
  • Transcription
  • Mitosis

The physical location of a gene on a chromosome is known as the:

<p>Locus (D)</p> Signup and view all the answers

What is the term for an individual with two different alleles for a specific gene?

<p>Heterozygote (C)</p> Signup and view all the answers

What is the primary purpose of the approximately 2-3% of human DNA directly involved in protein production?

<p>To produce at least 100,000 proteins (B)</p> Signup and view all the answers

Which of the following is an example of an epigenetic change?

<p>Methylation of DNA (A)</p> Signup and view all the answers

What is the term for the existence of two or more alleles at a locus, resulting in multiple genotypes?

<p>Polymorphism (A)</p> Signup and view all the answers

What is the primary function of a codon?

<p>To code for a specific amino acid, which is used to build proteins. (B)</p> Signup and view all the answers

Which of the following best describes the relationship between a gene and a protein?

<p>One gene typically codes for a single protein. (D)</p> Signup and view all the answers

In the context of DNA structure, what are the 'rungs' of the double helix composed of?

<p>Nitrogenous base pairs, specifically adenine-thymine and cytosine-guanine. (C)</p> Signup and view all the answers

Which of the following is considered the ultimate source of all new genetic variation?

<p>Mutations in the DNA base sequence. (B)</p> Signup and view all the answers

What is the primary significance of neutral mutations in evolution?

<p>They can increase the importance of genetic drift and may become advantageous in the future. (B)</p> Signup and view all the answers

Which farming practices are described in the provided text?

<p>Slash and burn with iron tools (C)</p> Signup and view all the answers

What is gel electrophoresis used to assess in the context of genetics?

<p>Differences in the amino acid sequence of the same protein between individuals. (C)</p> Signup and view all the answers

Which of the following is NOT a known 'force of evolution'?

<p>Gel electrophoresis. (A)</p> Signup and view all the answers

A person with the 'AS' genotype for hemoglobin will MOST likely experience:

<p>Sickle cell trait with less severe symptoms (A)</p> Signup and view all the answers

What is the primary vector for the parasite Plasmodium falciparum?

<p>Anopheles mosquitos (D)</p> Signup and view all the answers

Which of the following is a true statement regarding mutations?

<p>Mutations occur randomly in a genome and are rare. (D)</p> Signup and view all the answers

In the life cycle of the parasite responsible for malaria, where does uncontrolled reproduction primarily occur in humans?

<p>Red blood cells (B)</p> Signup and view all the answers

Sickle cell anemia is primarily found in people of which ancestry?

<p>West African descent (D)</p> Signup and view all the answers

What effect does decreased oxygen pressure have on hemoglobin and red blood cells?

<p>Decreased oxygen loading and decreased lifespan (A)</p> Signup and view all the answers

What genetic pattern is associated with the inheritance of sickle cell trait?

<p>Codominance (D)</p> Signup and view all the answers

What is a characteristic of disruptive selection?

<p>Both homozygotes are fitter than the heterozygote in monogenic traits and extremes are fitter in polygenic traits (B)</p> Signup and view all the answers

Which factor does NOT primarily influence the extent of genetic drift within a population?

<p>The rate of gene flow into the population (D)</p> Signup and view all the answers

What is the primary outcome of genetic drift when it is the only evolutionary force acting on a population?

<p>Fixation of certain alleles and loss of others (C)</p> Signup and view all the answers

Which of the following scenarios best represents the concept of the founder effect?

<p>A small group of individuals migrates to a new area and establishes a new, isolated population. (C)</p> Signup and view all the answers

In the context of population genetics, what does 'effective population size' refer to?

<p>The number of individuals that are actively contributing to the next generation (D)</p> Signup and view all the answers

Which of the following is NOT an example of microevolutionary change observed in recent human history (last 10,000 years)?

<p>The emergence of bipedalism (D)</p> Signup and view all the answers

The Amish population's high rate of Ellis-van Creveld syndrome is a classic example of:

<p>The founder effect (A)</p> Signup and view all the answers

What distinguishes the bottleneck effect from the founder effect in population genetics?

<p>The bottleneck effect is due to a population crash, while the founder effect is due to the establishment of a new colony. (D)</p> Signup and view all the answers

What is the relationship between an organism's fitness and its number of surviving offspring?

<p>Fitness is directly related to the number of offspring that survive to reproductive age. (B)</p> Signup and view all the answers

What is the primary focus of macroevolutionary studies?

<p>Reconstructing phylogenies and examining large-scale genetic changes over long periods. (C)</p> Signup and view all the answers

According to Ernst Mayr's definition, what is the primary criterion for classifying organisms within the same species?

<p>Ability to produce viable and fertile offspring. (B)</p> Signup and view all the answers

What is the key distinction between parallel and convergent evolution?

<p>Parallel evolution occurs due to similar environmental stress, whereas convergent evolution is due to occupying similar environments. (D)</p> Signup and view all the answers

What does the concept of 'hybrid vigor' refer to?

<p>An increased viability and fitness in hybrid offspring, even if they are sterile. (D)</p> Signup and view all the answers

In the context of the leopard frog example, what is observed regarding phenotypic differences with geographic distance?

<p>Adjacent groups exhibit similar phenotypes, with differences increasing with spatial separation. (A)</p> Signup and view all the answers

What is the significance of 'reproductive isolation' according to the material?

<p>It's a generally adequate, but not always perfect, definition of a species. (C)</p> Signup and view all the answers

If a population has 50 individuals with the genotype AA and 50 with the genotype BO at a given locus, what is the frequency of the A allele?

<p>$0.50$ (A)</p> Signup and view all the answers

According to the text what is the 'primary unit of evolution'?

<p>The breeding population (A)</p> Signup and view all the answers

What is the primary effect of gene flow on genetic variation within a breeding population?

<p>It increases genetic diversity by introducing new alleles. (B)</p> Signup and view all the answers

In the context of natural selection, what does 'differential mortality' refer to?

<p>The increased death rate in individuals with unfavorable traits. (C)</p> Signup and view all the answers

During the drought of 1977 in the Galapagos, what was the primary reason that larger medium ground finches were more likely to survive?

<p>They possessed stronger beaks to crack the larger seeds. (C)</p> Signup and view all the answers

What is the key difference between a polygenic trait and a monogenic trait, regarding directional selection, demonstrated in the text?

<p>Polygenic traits involve a continuous range of phenotypes, while monogenic traits have distinct phenotypes. (C)</p> Signup and view all the answers

What environmental change caused the shift in peppered moth populations from predominantly light-colored to predominantly dark-colored?

<p>Industrial pollution darkening tree trunks. (B)</p> Signup and view all the answers

In stabilizing selection, how does the heterozygote compare to both homozygotes as it relates to fitness?

<p>The heterozygote has a higher fitness than both homozygotes. (C)</p> Signup and view all the answers

What is the significance of 'balanced polymorphism' in the context of sickle cell anemia?

<p>It refers to a situation where heterozygotes have an advantage that maintains multiple alleles. (C)</p> Signup and view all the answers

Why was the S allele for sickle cell anemia more frequent in some African populations than in the US?

<p>Because the gene for SCA is advantageous in environments with high rates of malaria. (B)</p> Signup and view all the answers

What was a critical change that led to an increase in malaria cases according to the content provided?

<p>The shift of some african populations from hunter gatherer to a sedentary lifestyle (B)</p> Signup and view all the answers

According to the text provided, what is one of the characteristics of an environment that can maintain a balanced polymorphism?

<p>An environment where heterozygotes have a greater survival advantage. (A)</p> Signup and view all the answers

What best describes the typical trend in body size of the medium ground finches after the return of normal rainfall?

<p>Finch population started to show an average decrease in body size until 1983. (A)</p> Signup and view all the answers

What best describes the effect of an El Niño event on the medium ground finch population described in the text?

<p>It resulted in a heavy rainfall, causing an increase of smaller seeds and decrease in body size. (B)</p> Signup and view all the answers

According to what is described in the text, what was the main difference between plants living in low-lying and high-lying areas?

<p>Plants in low lying areas tend to produce large seeds with better access to ground water. (A)</p> Signup and view all the answers

In the context of natural selection, what is the key factor that results in changes of gene frequency within a population.

<p>Variation in the survival or reproduction rate caused by differences in traits. (A)</p> Signup and view all the answers

What is one of the conditions needed for natural selection to occur, according to the text provided?

<p>There needs to be a significant external pressure causing differential mortality. (A)</p> Signup and view all the answers

Flashcards

Blending Theory of Inheritance

A process where characteristics are inherited independently from each other, not blending together. This principle explains why offspring don't look like an average of their parents.

What are genes?

A physical unit of inheritance that carries a specific genetic instruction from parents to offspring. Genes determine traits like eye color or hair texture.

What are alleles?

A specific version of a gene that influences a certain trait. For example, there's a gene for eye color, and its alleles can be brown, blue, or green.

Homozygous

When an organism carries two copies of the same allele for a trait. For example, a plant with two alleles for round seeds would be homozygous for round seeds.

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Heterozygous

When an organism carries two different alleles for a trait. For example, a plant with one allele for round seeds and one for wrinkled seeds would be heterozygous for seed shape.

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Genotype

The genetic makeup of an organism, represented by the specific combination of alleles it carries. For example, the genotype for a plant with round seeds could be RR or Rr.

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Phenotype

The observable characteristics of an organism resulting from its genotype. For example, the phenotype for a plant with round seeds would be having round seeds, regardless of the specific genotype.

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Monogenic Trait

A trait that is influenced by only one gene. Such traits often show distinct categories, like having either blue or brown eyes.

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Codon

Units of DNA that code for a specific amino acid. Three consecutive bases make up a codon.

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Mutations

Changes in the sequence of DNA bases.

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Neutral Mutation

A type of mutation where the change in the codon sequence is neither beneficial nor harmful.

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Evolution

The process where the frequency of alleles in a population changes over generations.

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Mutations

The ultimate source of new genetic variation.

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Regulatory Gene

A type of gene that regulates other genes, affecting their expression.

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Homeobox Gene (Hox Gene)

A type of regulatory gene responsible for body plan development.

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One Gene-One Protein Model

The idea that one gene codes for one specific protein.

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Slash and burn farming

A type of farming using iron tools to clear land, where crops are grown until the soil is depleted, and the field is then abandoned.

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Sickle Cell Anemia (SCA)

A mutation in the gene responsible for hemoglobin production, resulting in abnormal red blood cells, especially found in people of West African descent.

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Sickle Cell Trait (AS)

A genetic condition where individuals carry the sickle cell trait (AS) and are less likely to be hospitalized with severe malaria. This provides a survival advantage in areas where malaria is prevalent.

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Plasmodium falciparium

The single-celled parasite responsible for causing malaria, transmitted through the bite of infected mosquitos.

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Codominance

A genetic pattern where both alleles of a gene are expressed in a heterozygote, resulting in a phenotype that combines both alleles.

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Disruptive Selection

A type of natural selection where individuals with extreme phenotypes are more likely to survive and reproduce, leading to a divergence of the population towards these extremes.

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Polygenic Trait

A trait controlled by multiple genes.

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Macroevolution

Evolutionary changes that occur over long periods, resulting in large-scale transformations such as extinction and speciation.

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Population Genetics

The study of how gene frequencies change within a population over time.

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Synthetic Theory of Evolution

A hypothesis proposing that evolution occurs primarily through the gradual accumulation of small genetic changes within populations.

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Hardy-Weinberg Theorem

A principle stating that allele frequencies remain constant in a population from generation to generation, under specific conditions.

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Biological Species Concept

A group of organisms that can interbreed and produce fertile offspring.

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Convergent Evolution

The process where two species with a distant common ancestor evolve similar traits due to similar environmental pressures.

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Parallel Evolution

The process where two species with a shared ancestor evolve in similar ways due to experiencing similar environmental conditions.

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Hybridization

The mixing of genes between two distinct species, often resulting in hybrid offspring.

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Fitness

A measure of an organism's reproductive success, determined by the number of offspring that survive to reach reproductive age.

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Genetic Drift

A change in the genetic makeup of a population over time, resulting from random fluctuations in allele frequencies.

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Founder's Effect

The process where a new population is established from a small number of individuals from a larger population, potentially leading to a different allele frequency distribution.

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Bottleneck Effect

A drastic reduction in population size due to a catastrophic event, leading to a loss of genetic diversity and potentially altering the allele frequencies.

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Effective Population Size

The genetic variation present in a population is determined by the effective population size, which comprises the individuals that are actually contributing to the next generation.

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Gene Flow

The process of gene flow between populations, which can prevent genetic divergence and maintain genetic similarity.

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Adaptedness

A concept that refers to how well an organism is adapted to its specific environment. It is closely related to fitness, but focuses on the characteristics of the organism rather than its reproductive success.

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Natural Selection

A change in the genetic makeup of a population over time due to differential survival and reproduction of individuals with certain traits.

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Directional Selection

A type of natural selection where the average trait value of a population shifts towards one extreme. This occurs when one phenotype is consistently favored over others.

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Directional Selection (Example)

The medium ground finch population on the Galapagos Islands changed dramatically during a severe drought. Larger beaked birds were better able to eat the remaining seeds, leading to an increase in average beak size in the next generation. The change in phenotype was due to a change in the environment.

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Stabilizing Selection

A type of natural selection where individuals with intermediate traits have the highest probability of survival. This can lead to the maintenance of genetic diversity within a population.

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Stabilizing Selection (Example)

Sickle cell anemia is a genetic disorder where red blood cells have an abnormal shape. Although individuals with two copies of the sickle cell allele (SS) experience severe health problems, individuals with one copy of the sickle cell allele (AS) have increased resistance to malaria. This leads to a balanced polymorphism, where both the S and A alleles are maintained in the population.

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Survival of the Fittest

Organisms with advantageous traits are more likely to survive and reproduce, passing on those traits to their offspring. This leads to a gradual shift in the population towards those advantageous traits.

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Genetic Diversity

The genetic variation within a population is critical for its ability to adapt to changing environments. Gene flow can increase genetic diversity within a population.

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Mate Exchange

The process where genetic information is exchanged between populations. This exchange can lead to a decrease in genetic differences between populations.

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Virgin Population

A population that has not been exposed to a particular virus or pathogen. This population might be more susceptible to disease.

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Virulence

The ability of a virus to cause disease. A virus that is less virulent is less likely to cause severe illness.

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Study Notes

Blending Theory of Inheritance

  • Gregor Mendel (1822-1884) conducted experiments on pea plants, using 28,000 plants and 400,000 seeds.
  • His research demonstrated discrete combinations of traits, not blending.

Mendelian Inheritance

  • Inheritance involves physical units (genes) that maintain their identity from parents to offspring.
  • Dominant, recessive, and codominance describe relationships between different forms of the same gene (alleles).
  • A Locus is the physical location of a gene on a chromosome.
  • Alleles are different forms of a gene.
  • Homozygotes have two identical alleles, while heterozygotes have two different alleles.
  • Genotype is the specific combination of alleles, phenotype is the morphological result of the genotype.
  • Monogenic traits are determined by single genes, while polygenic traits are influenced by multiple genes.
  • Polymorphism refers to the existence of multiple allele forms at a single locus.

Chromosomes

  • Chromosomes are containers of DNA.
  • Humans have 23 pairs of chromosomes (46 total) in each cell, one from each parent.

DNA Structure and Function

  • Humans have approximately 21,000 genes.
  • These produce at least 100,000 proteins.
  • Non-coding RNA plays a role in gene regulation.
  • Epigenetics describes heritable changes in gene expression due to non-DNA changes.
  • Exons are coding regions, introns are non-coding regions.
  • Codons are three-base sequences that code for specific amino acids, which assemble into proteins.
  • Genes' function is the determination of protein structure and function.
  • DNA structure is a double helix with base pairs (Adenine-Thymine, Cytosine-Guanine).

Meiosis and Mitosis

  • Meiosis is cell division producing gametes (egg and sperm).
  • Mitosis is cell division in all other cells.
  • Mitosis occurs in somatic cells creating identical daughter cells.
  • Meiosis creates sex cells (gametes) with half the number of chromosomes.

Evolution and Variation

  • The ultimate source of new genetic variation is change in DNA base sequences.
  • Mutation rates are random.
  • Genetic variation within a population.
  • Gene flow involves the movement of individuals and genes between populations.
  • Evolutionary factors (like natural selection and drift) can influence gene frequency within populations.
  • Natural selection acts on phenotypes, favoring those beneficial in a given environment leading to greater fitness.
  • Neutral mutations occur in genes where no selection for or against the mutation exists.
  • The founder effect occurs when a new population is established by a small group of individuals.
  • Genetic drift changes allele frequencies due to random events.
  • Balanced polymorphisms occur where multiple alleles persist at stable frequencies.
  • Evolution happens in populations over generations

Environmental Influences and Phenotypic Variation

  • Organisms are best-adapted to their environments.
  • Directional selection shifts to the phenotype favoured by the environment's stresses
  • Environmental influences can lead to phenotypic change.

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