Mendelian Genetics and Probability lecture 19

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Questions and Answers

If a plant species exhibits incomplete dominance for flower color, where RR produces red flowers, rr produces white flowers, and Rr produces pink flowers, what percentage of offspring from a cross between two pink-flowered plants (Rr x Rr) will have red flowers?

  • 50%
  • 25% (correct)
  • 0%
  • 75%

The law of independent assortment states that genes for different traits are always inherited together.

False (B)

What term describes a situation where one gene influences multiple, seemingly unrelated phenotypic traits?

pleiotropy

In a scenario where a single gene controls the color of a certain flower but the environment, particularly soil pH, can alter the expression of that gene, resulting in different shades of flower color. This is an example of the influence of ______ factors on the expression of a gene.

<p>environmental</p> Signup and view all the answers

Match the following genetic phenomena with their descriptions:

<p>Incomplete Dominance = Heterozygote expresses an intermediate phenotype. Codominance = Both alleles are equally expressed in the heterozygote. Polygenic Inheritance = Multiple genes contribute to a single phenotype. Environmental Influence = External conditions affect gene expression.</p> Signup and view all the answers

In a polygenic inheritance system, what happens to the number of distinct phenotypic classes as the number of involved genes increases?

<p>The number of phenotypic classes increases. (D)</p> Signup and view all the answers

Codominance is a form of gene interaction where one allele completely masks the effect of another allele at the same locus.

<p>False (B)</p> Signup and view all the answers

What is the phenotypic ratio expected in the F2 generation of a dihybrid cross when both genes assort independently and display complete dominance?

<p>9:3:3:1</p> Signup and view all the answers

The ABO blood group system in humans is an example of ______, where both A and B alleles are expressed in individuals with the AB genotype.

<p>codominance</p> Signup and view all the answers

Match each term with the most appropriate example:

<p>Polygenic Trait = Human height Incomplete Dominance = Pink flowers in snapdragons Codominance = ABO blood groups Environmental Influence on Phenotype = Hydrangea color change based on soil pH</p> Signup and view all the answers

A plant has three genes that affect height. Each dominant allele (A, B, C) adds 2 cm to a base height of 10 cm. What is the height of a plant with the genotype AabbCc?

<p>14 cm (A)</p> Signup and view all the answers

Environmental factors can only influence quantitative traits and have no impact on qualitative traits.

<p>False (B)</p> Signup and view all the answers

In a cross between two individuals with the genotype AaBbCc, where the genes assort independently, what is the probability of obtaining an offspring with the genotype AABBcc?

<p>1/64</p> Signup and view all the answers

When the heterozygote displays a phenotype that is intermediate between the phenotypes of both homozygotes, this pattern of inheritance is called ______.

<p>incomplete dominance</p> Signup and view all the answers

Match the following genetic terms with their correct definitions:

<p>Allele = An alternative form of a gene. Genotype = The genetic makeup of an organism. Phenotype = The observable characteristics of an organism. Locus = The specific location of a gene on a chromosome.</p> Signup and view all the answers

Which of the following genetic scenarios could result in a deviation from the expected Mendelian ratios?

<p>Linked genes close together on the same chromosome. (C)</p> Signup and view all the answers

If a gene is polymorphic, it means that every individual in a population must have a different version of that gene.

<p>False (B)</p> Signup and view all the answers

Explain how environmental factors can influence the expression of a single gene, using a specific example.

<p>The color of hydrangeas is determined by a single gene, but the soil pH (an environmental factor) affects its expression; in acidic soils, flowers are blue, while in alkaline soils, they are pink.</p> Signup and view all the answers

A statistical rule used to determine the probability of two independent events occurring together, by multiplying their individual probabilities, is known as the ______ rule.

<p>product</p> Signup and view all the answers

Match the statistical terms used in genetics with their correct application:

<p>Product Rule = Calculating probability of independent events occurring together. Sum Rule = Calculating probability of mutually exclusive events. Punnett Square = Predicting genotypes and phenotypes of offspring. Dihybrid Cross = Analyzing inheritance of two genes.</p> Signup and view all the answers

A cross between two plants yields offspring with a phenotypic ratio of 1:2:1 for a particular trait. Which inheritance pattern is most likely responsible for this ratio?

<p>Incomplete dominance (D)</p> Signup and view all the answers

Polygenic traits usually show distinct, discrete phenotypic categories, rather than a continuous range of variation.

<p>False (B)</p> Signup and view all the answers

In what situation would you apply the sum rule in genetic probability calculations?

<p>mutually exclusive events</p> Signup and view all the answers

A diagram that is used to predict the possible genotypes and phenotypes of offspring from a cross, based on the genotypes of the parents, is called a ______ square.

<p>punnett</p> Signup and view all the answers

Match each term with its example:

<p>Law of Segregation = Alleles separate during gamete formation. Law of Independent Assortment = Genes for different traits assort independently during gamete formation. Dihybrid Cross = SsYy x SsYy Product Rule = Probability of getting s and y.</p> Signup and view all the answers

An organism displays a trait that appears to be influenced by environmental factors, and its intensity varies among individuals with the same genotype. Which concept best describes this phenomenon?

<p>Variable expressivity (C)</p> Signup and view all the answers

If two genes are located very far apart on the same chromosome, they will always assort independently.

<p>True (A)</p> Signup and view all the answers

What is the phenotypic ratio expected from a testcross involving an individual heterozygous for two independently assorting genes?

<p>1:1:1:1</p> Signup and view all the answers

Genes that are located on the same chromosome are referred to as ______ genes.

<p>linked</p> Signup and view all the answers

Match the following genotype scenarios with correct term:

<p>Homozygous Dominant = AA Homozygous Recessive = aa Heterozygous = Aa Multiple Alleles = Eye color in Drosophila</p> Signup and view all the answers

Flashcards

Law of Segregation

Genes segregate at meiosis, each gamete getting one of the two alleles possessed by a parent.

Independent Assortment

Alleles of different genes assort independently during gamete formation.

Product Rule

To find the probability when events are independent, multiply individual probabilities.

Sum Rule

To find the probability when the events are 'mutually exclusive', add individual probabilities.

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Polymorphism

Many alleles exist for a single gene, leading to variation in a population.

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Incomplete Dominance

The F1 generation displays an intermediate phenotype.

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Co-Dominance

Both parental phenotypes are exhibited in the heterozygote.

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Polygenic Traits

Phenotype controlled by multiple genes that have an additive effect.

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Additive Effect

The total number of color-producing alleles dictates phenotypes.

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Environmental Effects

Environmental factors can influence how a gene expresses itself.

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Study Notes

Lecture 19 Objectives

  • Explain Mendelian inheritance based on probability laws
  • Identify deviations from Mendelian ratios such as incomplete dominance, co-dominance, and polymorphism
  • Discuss how the environment affects phenotype
  • Explain how several loci affect some phenotypic traits, which are polygenic traits

Mendelian Genetics & Probability

  • Genes segregate at meiosis, where each gamete contains only one allele possessed by the parent, which is Mendel's 1st Law (Law of Segregation)
  • Alleles of different genes assort independently during gamete formation, which is Mendel's 2nd Law (Independent Assortment)
  • Product Rule is used to calculate multiple probabilities for independently assorting genes
  • Offspring Probability Calculation*
  • To determine the probability of an offspring with a specific genotype
  • Multiply the probability of each parent contributing the necessary allele

Allelic Interactions and Apparent Deviations from Mendel's Laws

  • Polymorphism*
  • Polymorphism means one gene can have many alleles
  • An example would be eye color in Drosophila
  • Each individual can only have two alleles for a gene, one on each homologous chromosome

Incomplete Dominance

  • Incomplete dominance occurs when the F1 generation has an intermediate phenotype, suggesting blending inheritance.
  • The subsequent F2 generation includes parental phenotypes, rejecting blending inheritance in favor of particulate inheritance

Co-Dominance

  • Co-dominance occurs when both parental phenotypes are present in the F1 generation
  • An example is the ABO blood antigen system, where A and B alleles are co-dominant, and both antigens are expressed

Polygenic Traits

  • Polygenic traits are when a phenotype is controlled by many genes with an additive effect
  • Polygenic trait characters appear continuous or quantitative
  • Polygenic means there are non-discrete steps that create a range of phenotypes
  • Examples include skin color, weight, wool length, IQ, milk yield, and height
  • Polygenic traits are controlled by groups of genes

Skin Colour

  • Human skin color is coded by 3 genes, each with alleles coding for color (C) or no color (c)
  • The phenotype relates to the total number of color-producing alleles, from 0 (white) to 6 (black), known as an additive effect
  • Polygenic traits typically create a normal trait distribution in a population
  • The more genes involved, the higher the number of phenotypic classes

The Environment

  • The environment also affects phenotype
  • Examples include nutrition, height/weight, life expectancy, and disease
  • Hydrangeas are pink in alkaline soils and blue in acidic soils
  • The environment impacts phenotypes (e.g., wheat ear size) that have 1 gene and 2 alleles adn is additive
  • Continuous traits can have a simple genetic basis (e.g., 1 gene, 2 alleles)
  • 70% of color variation in the continuous traits with one gene and two alleles are explained by two alleles at a single gene called ebony

Lecture 19 Summary

  • Multiple probabilities for independently assorting genes are calculated using the product rule
  • Heterozygote phenotypes differ from homozygote phenotypes in cases of incomplete dominance or co-dominance
  • Polygenic traits create a wide range of phenotypes, with a normal distribution
  • Environmental variation smooths out the differences between genetically controlled phenotypes

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