Mendelian Genetics and Inheritance

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Questions and Answers

What is the central concept of Mendelian inheritance?

  • The blending of parental traits to create intermediate offspring traits.
  • The transmission of traits controlled by a single gene with two alternative alleles. (correct)
  • The inheritance of acquired characteristics from parents.
  • The transmission of traits controlled by multiple genes.

Which of the following statements accurately describes Gregor Mendel’s contribution to the field of genetics?

  • He discovered the structure of DNA.
  • He identified chromosomes as the carriers of genetic information.
  • He developed the theory of natural selection.
  • He formulated foundational principles of heredity through experimentation with pea plants. (correct)

In genetics, what distinguishes 'factors,' as described by Mendel, from what are known today as genes?

  • Factors control only physical traits, while genes control all traits.
  • Factors are only present in plants, while genes are present in animals.
  • Factors are inherited only from the mother, while genes are inherited from both parents.
  • There is no difference; Mendel simply used a different term before the concept of the gene was fully developed. (correct)

What is the primary focus of a monohybrid cross?

<p>Studying the inheritance pattern of a single gene. (B)</p> Signup and view all the answers

Before performing crosses, Mendel ensured that his pea plants were 'true-breeding'. What does 'true-breeding' mean in the context of genetics?

<p>The plants produced offspring with only the same traits as the parents when self-pollinated. (D)</p> Signup and view all the answers

In the context of Mendelian genetics, what is the F1 generation?

<p>The offspring resulting from the cross between two pure lines. (A)</p> Signup and view all the answers

What phenotypic ratio did Mendel consistently observe in the F2 generation of a monohybrid cross?

<p>3:1 (C)</p> Signup and view all the answers

Why is a Punnett square an important tool in studying genetics?

<p>It predicts the possible genotypes and phenotypes of offspring in a cross. (A)</p> Signup and view all the answers

In a monohybrid cross, if the F1 generation has a heterozygous genotype (Tt), what genotypes will be present in the F2 generation?

<p>TT, Tt, and tt (A)</p> Signup and view all the answers

How does the genotypic ratio differ from the phenotypic ratio in the F2 generation of a monohybrid cross?

<p>The genotypic ratio describes the actual genetic makeup, while the phenotypic ratio describes the observable traits. (C)</p> Signup and view all the answers

What is the significance of Mendel's conclusions about hereditary 'factors' in the F1 generation?

<p>One factor from each parent is contributed to the offspring. (A)</p> Signup and view all the answers

In the context of Mendelian inheritance, if both dominant and recessive factors are present in an offspring, which trait will be expressed?

<p>Only the dominant trait. (D)</p> Signup and view all the answers

What is the purpose of performing a dihybrid cross?

<p>To analyze how two different genes segregate and assort independently. (D)</p> Signup and view all the answers

In a dihybrid cross, what is produced by crossing round-yellow seeds (RRYY) with wrinkled-green seeds (rryy)?

<p>All round-yellow seeds (RrYy) (C)</p> Signup and view all the answers

In the F2 generation of a dihybrid cross, what phenotypic ratio typically results from the cross of two F1 generation plants (RrYy x RrYy)?

<p>9:3:3:1 (D)</p> Signup and view all the answers

What is the relationship between Mendel's Laws of Segregation and Independent Assortment?

<p>The Law of Segregation explains allele separation, while the Law of Independent Assortment explains how different genes independently separate during gamete formation. (B)</p> Signup and view all the answers

What does the Law of Segregation state?

<p>Each individual has two alleles for each trait, which separate during gamete formation. (B)</p> Signup and view all the answers

Which of the following is an example of the Law of Independent Assortment?

<p>The inheritance of height and flower color independently of each other. (A)</p> Signup and view all the answers

How does a dihybrid cross demonstrate the Law of Independent Assortment?

<p>By revealing that the inheritance of one trait does not affect the inheritance of another, provided the genes are not linked. (A)</p> Signup and view all the answers

Considering a dihybrid cross involving seed shape (R=round, r=wrinkled) and seed color (Y=yellow, y=green), what proportion of the F2 generation would be expected to have wrinkled seeds and yellow color?

<p>3/16 (B)</p> Signup and view all the answers

Mendel’s experimental approach was significant because it demonstrated the importance of which factor in scientific research?

<p>Focusing on easily observable traits and quantitative analysis. (D)</p> Signup and view all the answers

Why was it important for Mendel to use pure lines in his experiments?

<p>To ensure consistent and predictable results in subsequent crosses. (C)</p> Signup and view all the answers

What is the difference between a homozygous and a heterozygous genotype?

<p>A homozygous genotype has two identical alleles, while a heterozygous genotype has two different alleles. (A)</p> Signup and view all the answers

If 'T' represents the dominant allele for tallness and 't' represents the recessive allele for shortness in pea plants, what is the phenotype of a plant with the genotype 'Tt'?

<p>Tall (C)</p> Signup and view all the answers

What is the expected phenotypic ratio of a cross between two heterozygous individuals (Pp x Pp), where 'P' represents the dominant allele and 'p' represents the recessive allele?

<p>3:1 (B)</p> Signup and view all the answers

What is the purpose of test cross?

<p>To determine the genotype of an organism showing a dominant trait. (C)</p> Signup and view all the answers

Which cross could be used to perform a test cross?

<p>Tt x tt (D)</p> Signup and view all the answers

In a test cross, if all the offspring display the dominant trait, what can be inferred about the genotype of the parent with the dominant phenotype?

<p>It is homozygous dominant. (B)</p> Signup and view all the answers

What result from a test cross would indicate that the parent with the dominant phenotype is heterozygous?

<p>Half of the offspring display the dominant trait, and half display the recessive trait. (A)</p> Signup and view all the answers

How does understanding Mendelian inheritance contribute to modern genetics?

<p>It provides the foundational principles for understanding genetic inheritance and predicting genetic outcomes. (A)</p> Signup and view all the answers

Flashcards

What is inheritance?

The passing of traits from parents to offspring.

What is Mendelian inheritance?

Crosses involving a single gene with two alternative alleles.

What are Mendelian crosses?

Experiments to study inheritance patterns.

What is a monohybrid cross?

A cross to study the inheritance of one single character.

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What is phenotype?

The observable characteristics of an organism.

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What is genotype?

The genetic makeup of an organism.

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What does homozygous mean?

Having two identical alleles for a trait.

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What does heterozygous mean?

Having two different alleles for a trait.

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What is self-cross?

Verifying the purity of plants through self-crossing - tall with tall, dwarf with dwarf

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What is the F1 generation?

The first generation of offspring from a cross.

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What is the F2 generation?

The second generation of offspring from a cross.

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What is a dominant allele?

An allele that is expressed even when a recessive allele is present.

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What is a recessive allele?

An allele that is only expressed when two copies are present.

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What is a Punnett square?

Chart used to predict genotypes and phenotypes of offspring.

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What is a dihybrid cross?

Cross involving two traits of individuals at a time.

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Study Notes

  • Genetics is the study of inheritance and variation in organisms

Mendelian Inheritance

  • Austrian monk Gregor Mendel first explained how characteristics are passed between generations in the mid-19th century
  • Mendel discovered the principles of heredity by experimenting with garden peas (Pisum sativum) for eight years
  • Mendel established different terminologies used in genetics, such as factors (later genes, alleles), dominant, recessive, genotype, homozygous, heterozygous, phenotype, and more
  • Mendelian inheritance is the patterns of inheritance of traits controlled by a single gene with two alternative alleles, from parent to offspring
  • Mendel's principles of heredity include the law of segregation and the law of independent assortment

Mendelian Crosses

  • Gregor Mendel, known as the father of genetics, experimented with pea plants (Pisum sativum)
  • Mendel studied seven pairs of different characters of pea plants with contrasting traits that exist in two forms
  • Examples of traits studied include seed shape (round vs. wrinkled), seed color (yellow vs. green), flower color (purple vs. white), and stem length (tall vs. short)
  • Mendel conducted monohybrid crosses, dihybrid crosses, and test crosses to determine the mechanism of inheritance

Monohybrid Cross

  • Involves the study of the inheritance of a single character from each parent
  • Mendel verified the purity of plants through self-crosses, ensuring tall plants produced only tall offspring and dwarf plants produced only dwarf offspring
  • Cross-pollination of pure lines for contrasting characters resulted in the F1 generation, where only one trait was visible
  • Self-pollination of the F1 generation gave rise to the F2 generation, where both traits were observed in a 3:1 ratio of dominant to recessive traits
  • Dominant traits appear in the F1 generation, while recessive traits appear for the first time in the F2 generation
  • Capital letters denote dominant alleles, and lowercase letters denote recessive alleles
  • A Punnett square is a chart used to determine the expected ratios of genotypes and phenotypes in offspring providing probabilities
  • The phenotypic ratio in the F2 generation is 3:1 (3 tall, 1 short), and the genotypic ratio is 1:2:1 (1 TT, 2 Tt, 1 tt)
  • Round (RR), yellow (YY), inflated (II), green (GG), purple (PP), axial (AA), and tall (TT) were identified as dominant traits, while wrinkled (rr), green (yy), constricted (ii), yellow (gg), white (pp), terminal (aa), and short (tt) were identified as recessive traits
  • Each parent starts with two hereditary "factors," one dominant and one recessive
  • Factors separate in the parent, with only one factor from each parent contributed to the offspring
  • Each offspring inherits one factor from each parent
  • If the dominant factor is present, it will be expressed, even if the recessive factor is also present
  • The recessive factor will be expressed if only recessive factors are present

Dihybrid Cross

  • A cross between two traits of individuals at a time
  • The cross between round-yellow seed (RRYY) and wrinkled-green seed (rryy) resulted in all round yellow seeds (RrYy) in the F1 generation
  • The cross between F1 generations (RrYy x RrYy) resulted in round-yellow, wrinkled-yellow, wrinkled-green, and round-green offspring
  • Phenotypic ratio of 9:3:3:1 (9 round-yellow, 3 round-green, 3 wrinkled-yellow, 1 wrinkled-green)
  • Genotypic ratio of 1:2:2:4:1:2:1:2:1
  • Mendel discovered the laws of segregation and independent assortment from monohybrid and dihybrid crosses

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