Membrane Proteins Overview

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14 Questions

What is the mechanism of action of Phospholipase A2?

Bind to negatively charged phospholipids inducing a conformational change

Which type of detergent can denature proteins?

Ionic detergents

What is the role of calcium in the catalysis of Phospholipase A2?

Positions the ester bond for cleavage

Which type of detergent lacks a charged group?

Non-ionic detergents

What type of membrane proteins contain membrane spanning α-helices?

Integral membrane proteins

Which type of membrane protein has hydrophobic side chains interacting with fatty acyl groups?

Integral membrane proteins

Which type of membrane proteins are responsible for antigen recognition in the T cell receptor?

Alpha-beta pair

How many membrane-spanning helices does the bacterial protein Rhodopsin have?

7

What is the structure of Aquaporin 0?

Homotetramer

Where are porins typically found?

Outer membrane of Gram-negative bacteria, mitochondria, and chloroplasts

What type of side chains line the pore of the transmembrane protein described in the text?

Hydrophilic

Which type of anchors are attached to the N-terminus of cytosolic proteins like v-src for membrane anchoring?

Fatty acyl groups

What is the name of the hydrocarbon chains attached to cysteine residues near the C-terminus for membrane anchoring?

Farnesyl and geranylgeranyl

Which type of anchors are mentioned in the text as exoplasmic anchors for glycoproteins?

GPI anchors

This quiz covers different types of membrane proteins, including integral or trans-membrane proteins, lipid-anchored membrane proteins, and peripheral membrane proteins. It discusses the characteristics of integral membrane proteins such as membrane-spanning alpha helices and hydrophobic amino acids. Test your knowledge on the structure and function of various membrane proteins.

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