Membrane Proteins Overview
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Questions and Answers

What is the mechanism of action of Phospholipase A2?

  • Bind to negatively charged phospholipids inducing a conformational change (correct)
  • Break ionic and hydrogen bonds with its charge
  • Solubilize membrane proteins by interacting with water
  • Interact with hydrocarbons due to its hydrophilic part
  • Which type of detergent can denature proteins?

  • Ionic detergents (correct)
  • Non-ionic detergents
  • Hydrophobic detergents
  • Amphipathic detergents
  • What is the role of calcium in the catalysis of Phospholipase A2?

  • Interacts with hydrocarbons
  • Binds to negatively charged phospholipids
  • Positions the ester bond for cleavage (correct)
  • Induces a conformational change in the enzyme
  • Which type of detergent lacks a charged group?

    <p>Non-ionic detergents</p> Signup and view all the answers

    What type of membrane proteins contain membrane spanning α-helices?

    <p>Integral membrane proteins</p> Signup and view all the answers

    Which type of membrane protein has hydrophobic side chains interacting with fatty acyl groups?

    <p>Integral membrane proteins</p> Signup and view all the answers

    Which type of membrane proteins are responsible for antigen recognition in the T cell receptor?

    <p>Alpha-beta pair</p> Signup and view all the answers

    How many membrane-spanning helices does the bacterial protein Rhodopsin have?

    <p>7</p> Signup and view all the answers

    What is the structure of Aquaporin 0?

    <p>Homotetramer</p> Signup and view all the answers

    Where are porins typically found?

    <p>Outer membrane of Gram-negative bacteria, mitochondria, and chloroplasts</p> Signup and view all the answers

    What type of side chains line the pore of the transmembrane protein described in the text?

    <p>Hydrophilic</p> Signup and view all the answers

    Which type of anchors are attached to the N-terminus of cytosolic proteins like v-src for membrane anchoring?

    <p>Fatty acyl groups</p> Signup and view all the answers

    What is the name of the hydrocarbon chains attached to cysteine residues near the C-terminus for membrane anchoring?

    <p>Farnesyl and geranylgeranyl</p> Signup and view all the answers

    Which type of anchors are mentioned in the text as exoplasmic anchors for glycoproteins?

    <p>GPI anchors</p> Signup and view all the answers

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