The skin and systemic diseases
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Questions and Answers

What is a characteristic rash associated with herpes simplex virus, mycoplasma, pneumonia, and hepatitis B/C?

  • Erythema multiforme (correct)
  • Vasculitis
  • Pyoderma gangrenosum
  • Erythema nodosum
  • Which skin reaction is associated with infections and includes Gianotti-Crosti syndrome?

  • Erythema Annulare Centrifugum
  • Toxic Erythema
  • Erythema Migrans
  • Erythema Nodosum (correct)
  • In which condition does the rash start on the trunk and then spreads to the limbs, looking 'morbilliform' (measles-like)?

  • Erythema Migrans
  • Pyoderma gangrenosum
  • Erythema Multiforme
  • Toxic Erythema (correct)
  • Which underlying systemic disease is associated with Pyoderma gangrenosum?

    <p>Inflammatory bowel disease (IBD)</p> Signup and view all the answers

    What condition may present with a reactive rash consisting of maculopapular erythema that blanches and can be mildly itchy?

    <p>Erythema multiforme</p> Signup and view all the answers

    Which skin reaction is associated with Streptococcal infection, TB, sarcoid, pregnancy, IBD, and Behcet disease?

    <p>Erythema Nodosum</p> Signup and view all the answers

    'Erythema Multiforme' is characteristic of which underlying disease?

    <p>Herpes simplex virus</p> Signup and view all the answers

    What type of hypersensitivity reaction is thought to result in Erythema Multiforme?

    <p>Type 4</p> Signup and view all the answers

    Which infection can be associated with Erythema Multiforme?

    <p>Trypanosomiasis</p> Signup and view all the answers

    What is the classic cutaneous manifestation of Erythema Multiforme Major?

    <p>Involvement of mucous membranes along with the classic cutaneous rash</p> Signup and view all the answers

    What treatment might be used for extensive cutaneous Erythema Multiforme?

    <p>Systemic steroids</p> Signup and view all the answers

    Which hormonal condition can cause hyperpigmentation?

    <p>Hyperthyroidism</p> Signup and view all the answers

    Which condition can lead to localized hypopigmentation?

    <p>Hypopituitarism</p> Signup and view all the answers

    What is the predominant symptom associated with Erythema Multiforme Minor?

    <p>No systemic symptoms</p> Signup and view all the answers

    Which skin condition is characterized by symmetrical velvety dark plaques usually affecting the neck, axillae, and arm flexures?

    <p>Acanthosis nigricans</p> Signup and view all the answers

    What does 'necrobiosis' in necrobiosis lipoidica indicate?

    <p>Necrosis of the connective tissue</p> Signup and view all the answers

    Which of the following is a common association of necrobiosis lipoidica?

    <p>Thyroid disease</p> Signup and view all the answers

    What may rapidly evolving acanthosis nigricans involving the lips, tongue, and palms indicate?

    <p>Underlying malignancy</p> Signup and view all the answers

    Which skin condition may improve by excluding ultraviolet light with daily sunblock application?

    <p>Melasma</p> Signup and view all the answers

    What is a recommended diagnostic test for rapidly evolving acanthosis nigricans?

    <p>Fasting glucose check</p> Signup and view all the answers

    'Replacement of degenerating collagen fibers with lipid material' is a characteristic feature of which skin condition?

    <p>Necrobiosis lipoidica</p> Signup and view all the answers

    What is the characteristic feature of piebaldism?

    <p>Triangular hypopigmented patches on the forehead and white forelock</p> Signup and view all the answers

    Which enzyme deficiency causes albinism?

    <p>Defective tyrosinase enzymes</p> Signup and view all the answers

    What skin condition is characterized by localized depigmentation that is sharply demarcated and symmetrical?

    <p>Vitiligo</p> Signup and view all the answers

    Which disease is associated with acanthosis nigricans due to the deposition of bile salts from liver disease, iron salts, drugs, or metallic salts?

    <p>Hemochromatosis</p> Signup and view all the answers

    What is a common cause of post-inflammatory pigmentation?

    <p>Lichen planus</p> Signup and view all the answers

    In malabsorption syndromes, pellagra, and scurvy, what skin manifestation is commonly observed?

    <p>Hyperpigmentation</p> Signup and view all the answers

    What condition is characterized by cutaneous T-cell lymphoma?

    <p>Mycosis fungoides</p> Signup and view all the answers

    Which skin condition is characterized by telangiectasia, reticulate pigmentation, atrophy, and loss of pigment?

    <p>Poikiloderma</p> Signup and view all the answers

    In which skin condition is there a gradual progression to infiltrated lesions, nodules, ulceration, and occasionally erythroderma in Sezary syndrome?

    <p>Poikiloderma</p> Signup and view all the answers

    Which pregnancy dermatosis usually starts in the striae of the abdomen during the third trimester and can become widespread?

    <p>Pemphigoid Gestationis</p> Signup and view all the answers

    Which skin condition may initially resemble Polymorphous eruption of pregnancy but then develops pemphigoid-like vesicles spreading over the abdomen and thighs?

    <p>Pemphigoid Gestationis</p> Signup and view all the answers

    Which skin condition is benign and presents as a non-specific pruritic papular rash that arises during pregnancy?

    <p>Prurigo Gestationis</p> Signup and view all the answers

    Which etiology is associated with Poikiloderma?

    <p>Idiopathic</p> Signup and view all the answers

    What is a distinguishing feature of Polymorphous eruption of pregnancy (PEP) compared to other pregnancy dermatoses?

    <p>Spares the umbilicus</p> Signup and view all the answers

    Which skin condition has a greater prevalence of premature and small-for-dates babies and a high recurrence rate?

    <p>Pemphigoid Gestationis</p> Signup and view all the answers

    What distinguishes Pemphigoid Gestationis from Polymorphous eruption of pregnancy?

    <p>Rare occurrence</p> Signup and view all the answers

    Which skin feature may be observed with Poikiloderma?

    <p>Reticulate pigmentation</p> Signup and view all the answers

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