18 Questions
Where do melanomas most commonly arise in men?
Lower back
What is one risk factor for developing melanomas?
High melanin production
At what stage is malignant melanoma totally curable?
If excised before invading the dermis
Which type of growth indicates vertical growth in melanoma development?
Elevated areas
What is a key feature of melanoma lesions compared to nevi?
Irregular contours
How does malignant melanoma spread initially?
Via lymphatics to regional lymph nodes
What is the most deadly primary skin cancer, other than the rare Merkel cell tumor?
Malignant melanoma
Which skin cancer has both vertical and horizontal growth phases but the prognosis is mainly related to the vertical growth stage?
Malignant melanoma
What is the primary environmental factor strongly associated with the majority of melanoma cases?
UV radiation from sunlight
In which percentage of patients is the risk of melanoma inherited as an autosomal dominant trait?
5-10%
Which site is NOT mentioned as a possible origin of melanoma apart from the skin?
Liver
What type of DNA damage caused by UV radiation can lead to accumulation of mutations in melanocytes over time?
Imperfect DNA repair
Which type of tumor is characterized by prominent 'cherry red' eosinophilic nucleoli and brown melanin pigment in the cytoplasm?
Malignant melanoma
Which condition is considered a PREMALIGNANT epidermal tumor?
Actinic keratosis
What is the most common gender affected by soft tissue tumors according to the text?
Males
Which syndrome mentioned in the text is associated with familial cases of soft tissue tumors?
Neurofibromatosis 1
Which type of tumor typically contains HMB-45 positive cells according to the text?
Malignant melanoma
Which type of tumor is characterized by varying size nuclei with prominent nucleoli and atypical mitosis?
Rhabdomyosarcoma
Test your knowledge on melanomas, including where they commonly arise, risk factors, and early detection. Learn about the importance of melanin in skin pigmentation and the curability of melanoma when detected early.
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