18 Questions
What is the mechanism of action of sucralfate in treating peptic ulcers?
It forms a protective layer over the ulcer bed.
What is the effect of H2 blockers on naproxen absorption?
It increases the dissolution rate of naproxen.
What is the mechanism of action of prostaglandin analogues in treating peptic ulcers?
They inhibit acid secretion and promote mucous and bicarbonate secretion.
What type of peptic ulcer is the most common?
Duodenum ulcer
What is the adverse effect of aluminium hydroxide?
Constipation
What is the mechanism of action of colloidal bismuth subcitrate?
It increases gastric mucosal PGE2, mucous, and HCO3 production.
What is the mechanism of action of proton pump inhibitors?
Inhibit H+/K+-ATPase pump
What is the mechanism of action of carbenoxolone?
It increases mucous production, especially thick, viscous mucous.
What is the effect of histamine on acid secretion?
Increases acid secretion
Which of the following is NOT a type of anti-H. pylori drug?
Carbenoxalone
What is the effect of PGE2 on acid secretion?
Decreases acid secretion
Why are proton pump inhibitors administered in enteric coated form or capsules?
To protect the drug from acid degradation
What is the effect of Vitamin C on Helicobacter pylori?
It has an anti-H. pylori effect
What is the main cause of gastroesophageal reflux disease?
Decreased forward movement of GIT
What is the function of the chemoreceptor trigger zone?
To stimulate the emetic centre
Which of the following is used to treat gastroesophageal reflux disease?
All of the above
What is the function of the nucleus tractus solitarius?
To relay afferent impulses from the GIT
What is apomorphine used for?
To stimulate the emetic centre
This quiz covers different types of peptic ulcers, including GERD, NSAID-induced ulcers, and Zollinger-Ellison syndrome, as well as treatments such as PPIs, H2 blockers, and their mechanisms of action.
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