Podcast
Questions and Answers
Match the antacid medication with its primary consideration.
Match the antacid medication with its primary consideration.
Calcium carbonate = May cause rebound hyperacidity Antacids in general = Neutralize stomach acid All antacids = Avoid taking within 1-2 hours of other medications
Match the H-2 receptor antagonist consideration with its appropriate detail.
Match the H-2 receptor antagonist consideration with its appropriate detail.
Cimetidine = Has high drug interaction risk H-2 receptor antagonists = Dosage adjustment for liver/kidney disease may be needed
Match the proton pump inhibitor (PPI) with its consideration.
Match the proton pump inhibitor (PPI) with its consideration.
PPIs = Bind to the H-K+ ATPase enzyme system Long-term PPI use = Increases risk of pneumonia
Match the mucosal protectant with its characteristic.
Match the mucosal protectant with its characteristic.
Match the antiflatulent with its consideration.
Match the antiflatulent with its consideration.
Match the antidiarrheal type with its mechanism of action.
Match the antidiarrheal type with its mechanism of action.
Match the characteristic with its antidiarrheal.
Match the characteristic with its antidiarrheal.
Match the laxative type with its mechanism of action.
Match the laxative type with its mechanism of action.
Match the laxative type with the considerations for its use.
Match the laxative type with the considerations for its use.
Match the antiemetic type with its mechanism of action.
Match the antiemetic type with its mechanism of action.
Match the antiemetic with its consideration.
Match the antiemetic with its consideration.
Match the medication with its indication.
Match the medication with its indication.
Match the medication with its nursing consideration.
Match the medication with its nursing consideration.
Match the laxative with its consideration.
Match the laxative with its consideration.
Match the term regarding anti-diarrheal medications to its definition.
Match the term regarding anti-diarrheal medications to its definition.
Match the term regarding antiemetic medications to its definition.
Match the term regarding antiemetic medications to its definition.
Match the term regarding medications for the urinary tract to its definition.
Match the term regarding medications for the urinary tract to its definition.
Match the condition to its characteristic.
Match the condition to its characteristic.
Match consideration with H-2 Receptor Antagonists
Match consideration with H-2 Receptor Antagonists
Match consideration with PPIs
Match consideration with PPIs
Flashcards
Antacids: Action
Antacids: Action
Neutralizes stomach acid, raising pH.
H-2 Receptor Antagonists: Action
H-2 Receptor Antagonists: Action
Block histamine action at H2 receptors in parietal cells.
Proton Pump Inhibitors (PPIs): Action
Proton Pump Inhibitors (PPIs): Action
Binds to H+-K+ ATPase, inhibiting hydrochloric acid secretion.
Mucosal Protectants: Action
Mucosal Protectants: Action
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Antiflatulents: Action
Antiflatulents: Action
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Adsorbents (Antidiarrheals): Action
Adsorbents (Antidiarrheals): Action
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Antimotility Agents: Action
Antimotility Agents: Action
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Probiotics: Action
Probiotics: Action
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Fiber: Action
Fiber: Action
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Stool Softeners: Action
Stool Softeners: Action
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Osmotic Agents: Action
Osmotic Agents: Action
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Lubricants: Action
Lubricants: Action
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Stimulant Laxatives: Action
Stimulant Laxatives: Action
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Anticholinergics (Antiemetics): Action
Anticholinergics (Antiemetics): Action
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Antihistamines (Antiemetics): Action
Antihistamines (Antiemetics): Action
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Dopamine Antagonists (Antiemetics): Action
Dopamine Antagonists (Antiemetics): Action
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Prokinetics (Antiemetics): Action
Prokinetics (Antiemetics): Action
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Serotonin Antagonists (Antiemetics): Action
Serotonin Antagonists (Antiemetics): Action
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Phenazopyridine (Pyridium): Action
Phenazopyridine (Pyridium): Action
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Desmopressin: Action
Desmopressin: Action
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Study Notes
- Study notes on medications
Antacids
- Neutralize stomach acid, increasing pH
- Taken 3-4 times a day Interactions occur, avoid taking with other medications for 1-2 hours.
- Calcium carbonate might be contraindicated in clients who have kidney disease due to risk of hypercalcemia
- May cause rebound hyperacidity
- Encourage patients to stop smoking and to avoid alcohol, high-fat foods, spicy foods, and caffeine
H-2 Receptor Antagonists
- Blocks histamine's action at H2 receptors of stomach's parietal cells
- Take 15-60 minutes before foods that cause heartburn
- Possible dosage adjustments needed for liver or kidney disease
- Cimetidine poses a high risk of drug interactions
Proton Pump Inhibitors
- Binds to H+-K+ ATPase enzyme system, also known as proton pump
- Inhibits hydrochloric acid secretion
- May interfere with liver drug metabolism
- Long-term risks include zinc/magnesium/B12 deficiency, increased pneumonia risk, renal dysfunction, osteoporosis, and lupus erythematosus.
Mucosal Protectants
- These cover and protect GI ulcers from further attack by acid, pepsin, and bile salts
- Take on an empty stomach 2 hours after or 1 hour before meals
- Use cautiously in patients who have chronic renal failure to avoid excretion of small amounts of absorbed aluminum
- Side effect is constipation
Antiflatulents
- Alters elasticity of gas bubbles, breaking them into smaller bubbles
- Simethicone should be taken four times a day, after meals and at bedtime
- Safe for infants
- Common side effects include nausea, constipation, diarrhea, and headache
- Encourage position change, movement and avoidance of straws
Antidiarrheals
- Three types exist: adsorbents, anti-motility, and probiotics
Adsorbents
- Adsorption involves the adhesion of molecules to a surface
- Coats walls of GI tract
- Binds to causative bacteria or toxins
- Eliminates bacteria or toxins from the GI tract
- Examples include bismuth
- Reduce inflammation in intestine and the flow of fluids and electrolytes into bowel
- Salicylate is contained in Bismuth, avoid when taking aspirin
- Assess for Reye's Syndrome
- Contradictions exist with ulcer or bleeding problems
- Side effects include black or dark tongue and ringing in the ears
Antimotility Agents
- Decreases flow of fluids and electrolytes into the bowel
- Slows bowel movement
- Two examples are opioid-like and anticholinergics
Opioid-like
- Slows down the movement of intestines, thus reducing frequency and volume of bowel movements
- The structure is opioid-like, but causes fewer CNS effects
- Loperamide is an example
- Taking >rx abnormal heart rhythm
- Side effects include abdominal discomfort, N/V, dizziness, and drowsiness
Anticholinergics (Antispasmodics)
- Blocks action of acetylcholine (ACh) in nervous system
- Works on smooth muscle of GI tract to inhibit propulsive motility
- Decreases gastric acid secretion and cramping
- Examples include dicyclomine (Bentyl) and hyoscyamine (Levsin)
- Assess for intestinal obstruction
- Should not be taken in the presence of glaucoma, myasthenia gravis, or paralytic ileus
- Side effects include dry mouth, constipation, blurred vision, and confusion
Probiotics
- Microorganisms that help replenish normal bacteria flora in GI tract
- Lacta bacillus is an example
- Various strains exist with differing health benefits
- Side effects include gas, bloating, and diarrhea
Laxatives
- Different types of laxatives listed include Fiber, Stool Softeners, Osmotic agents, Lubricants, and Stimulant Laxatives
Fiber
- Adds bulk to stool to facilitate passage
- May affect GI absorption; take two hours before other meds
- Produces a BM in 12-72 hours
- Start on one dose per day, increase to 3 doses per day if needed to maintain soft stools
Stool Softeners (Emollient Laxatives)
- Facilitates movement of water and fats into stool
- Produces a BM in 1-72 hours
- Monitor electrolyte imbalances
- May interact with blood thinners and antibiotics
Osmotic Agents (Lubricant Laxatives)
- Causes water to be retained with the stool, increasing the number of bowel movements and softening the stool for easier passage
- Usually produces a BM in 1-3 days
- May cause diarrhea, abdominal cramping, and electrolyte imbalances
Lubricants
- Mineral oil coats stool to help seal in H2O
- Ex: Mineral Oil enema (fleet enema)
- Produce BM in 2-15 minutes (rapid BM)
- Side effects include: stomach cramps, bloating, diarrhea, dehydration, and electrolyte imbalances
Stimulant Laxatives
- BM happens in 15 minutes
- Causes contraction of intestines and stimulates stool to move
- PO or Rectal Supply
- Avoid long term use
- Can cause dehydration, electrolyte imbalances, chronic constipation & laxative dependency
- Side effects include abdominal cramps, nausea, vomiting, and diarrhea
Antiemetics
- Stop the process of vomiting
- Target specific neuroreceptors and interact with vomiting center (VC) and chemoreceptor trigger zone (CTZ)
- Types of antiemetics are anticholinergics, antihistamines, dopamine antagonists, prokinetics, and serotonin antagonists
Anticholinergics
- Block acetylcholine receptors, preventing nausea-inducing stimuli
- Example: Scopolamine = Transdermal patch!
- Side effects include Seizures!, Psychosis, and drowsiness!
Antihistamines
- Anti-Vertigo
- Block H1 receptors, thus preventing motion sickness
- Ex. Meclizine
- Side effects include drowsiness, dry mouth, and blurred vision
Dopamine Antagonists
- Blocks dopamine in the CTZ
- Side effects are drowsiness, Restlessness, dry mouth, and constipation
Prokinetics
- Increase GI movement and reduce nausea
- Blocks dopamine and acetylcholine, helping to promote motility
- Contradicted with GI hemorrhage, obstruction or perforation
- *Used post-opp
- Side effects = hypertensive Crisis or Seizure, suicidal thoughts
Serotonin Antagonists
- Block serotonin receptors
- May cause HA, Constipation, prolonged QTI Range
Nursing Considerations for Antiemetics
- Varied side effects depending on type
- Monitor for potential interactions
Phenazopyridine (Pyridium)
- Local anesthetic for lining of urinary tract
- Indication is dysuria
- Available OTC, but higher doses require prescription
- Excreted in urine and may cause it to turn orange/red
Desmopressin
- Synthetic version of ADH (vasopressin), a selective agonist of V2 receptors in renal collecting duct
- Increases H2O re-absorption & reduces urine production
- Indications include antidiuretic in diabetes insipidus and bedwetting
- Available as a nasal spray and tablet
- Take at night for bedwetting
- Many drug interactions occur
- Monitor BP
- Can cause hyponatremia, HA, dizziness, restlessness edema, N/V
Tamsulosin (Flomax)
- Blocks alpha receptors, relaxing muscles in prostate & bladder
- Indications include benign prostatic hyperplasia and kidney stone
- Monitor I & O, daily weight & BP
- Not enough data regarding pregnancy
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