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Chapter 2 pharm
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Chapter 2 pharm

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Questions and Answers

What is the study of how various drug forms influence the way in which the drug affects the body?

  • Pharmacotherapeutics
  • Pharmaceutics (correct)
  • Pharmacokinetics
  • Pharmacodynamics
  • What is the primary organ responsible for the metabolism of drugs?

  • Heart
  • Liver (correct)
  • Brain
  • Kidneys
  • What is the transport of a drug by the bloodstream to its site of action called?

  • Distribution (correct)
  • Excretion
  • Absorption
  • Dissolution
  • Which area has slow distribution of drugs in the body?

    <p>Muscle</p> Signup and view all the answers

    What is the movement of a drug from its site of administration into the bloodstream for distribution to the tissues called?

    <p>Absorption</p> Signup and view all the answers

    Which drug is an example of therapeutic use classification?

    <p>Penicillin</p> Signup and view all the answers

    What is the elimination of drugs from the body called?

    <p>Excretion</p> Signup and view all the answers

    What does pharmacokinetics study?

    <p>What happens to a drug from the time of administration to when it is all gone from the body.</p> Signup and view all the answers

    Which organ is most responsible for the metabolism of drugs?

    <p>Liver</p> Signup and view all the answers

    What is pharmacodynamics the study of?

    <p>What the drug does to the body.</p> Signup and view all the answers

    Which area has rapid distribution of drugs in the body?

    <p>Heart</p> Signup and view all the answers

    What is the science of the adverse effects of drugs and other chemicals on living organisms?

    <p>Toxicology</p> Signup and view all the answers

    What is the term for the large proportion of a drug which is chemically changed into inactive metabolites by the liver?

    <p>First pass effect</p> Signup and view all the answers

    What is the term for the time required for half of a given drug to be removed from the body?

    <p>Half-Life</p> Signup and view all the answers

    Which therapy is used for the treatment of chronic illness?

    <p>Maintenance therapy</p> Signup and view all the answers

    What is the term for drug therapy provided to prevent illness and other undesirable outcomes during planned events?

    <p>Prophylactic therapy</p> Signup and view all the answers

    Which term refers to the highest blood level of a drug?

    <p>Peak level</p> Signup and view all the answers

    Which type of reaction occurs in only a small percentage of patients receiving the drug and is unpredictable?

    <p>Idiosyncratic reactions</p> Signup and view all the answers

    What is an example of supplemental therapy?

    <p>Administration of insulin</p> Signup and view all the answers

    What is the range between when a drug is toxic or not called?

    <p>Therapeutic index</p> Signup and view all the answers

    Which term refers to the lowest blood level of a drug?

    <p>Trough level</p> Signup and view all the answers

    What is used to make the patient feel comfortable and relieve their pain and symptoms, with a goal of treating the patient and their family during the end stages of an illness when attempts at curative therapy have failed?

    <p>Palliative therapy</p> Signup and view all the answers

    What type of reaction does Steven Johnson Syndrome represent?

    <p>Adverse drug reaction</p> Signup and view all the answers

    You need to know the ________ name of medications.

    <p>Generic</p> Signup and view all the answers

    First drug in a class of drugs.

    <p>Prototypical drugs</p> Signup and view all the answers

    Drugs are grouped together based on similar properties into two classifications. What are they?

    <p>Structure and Therapeutic</p> Signup and view all the answers

    Beta Blockers are an example of what drug classification?

    <p>Structure</p> Signup and view all the answers

    Dissolving of solid dosage forms and their absorption is:

    <p>Dissolution</p> Signup and view all the answers

    Drugs are distributed first to those areas with extensive blood supply.

    <p>True</p> Signup and view all the answers

    The primary organ responsible for elimination is the

    <p>kidneys</p> Signup and view all the answers

    The study of plants and animals

    <p>Pharmacognosy</p> Signup and view all the answers

    What you have left over of the medication after metabolism is

    <p>Bioavailability</p> Signup and view all the answers

    The clinical use of drugs to prevent and treat diseases.

    <p>Pharmacotherapeutics</p> Signup and view all the answers

    _________ occurs if the peak blood level of the drug is too high.

    <p>Toxicity</p> Signup and view all the answers

    Match

    <p>Acute therapy = used to treat the critically ill often to sustain life or treat disease Maintenance therapy = An example of this would be the treatment of HTN Supplemental therapy = Supplies the body with a substance to maintain normal function Supportive therapy = Used to maintain the integrity of body functions while the patient is recovering from illness or trauma.</p> Signup and view all the answers

    An example of ____________ therapy is administering fluids when a patient is dehydrated or blood to a patient who lost blood during surgery.

    <p>Supportive therapy</p> Signup and view all the answers

    Match

    <p>Medication errors = These can occur during prescribing, dispensing, administering, and monitoring Prophylactic therapy = An example of this is the use of preoperative antibiotics for surgical procedures Acute therapy = Examples of this include vasopressors, volume expanders, and intensive chemo Antidotes = These have antagonistic effects</p> Signup and view all the answers

    Study Notes

    Drug Forms and Body Effects

    • Study of how drug forms affect body responses is known as pharmacokinetics.
    • Metabolism of drugs primarily occurs in the liver.
    • Transport of a drug through the bloodstream to its site of action is termed distribution.
    • Organs with slow drug distribution include adipose (fat) tissue.
    • Movement of a drug from administration site to bloodstream is called absorption.

    Drug Classifications and Uses

    • An example of therapeutic use classification is antibiotics.
    • Elimination of drugs from the body is referred to as excretion.
    • Pharmacokinetics studies absorption, distribution, metabolism, and excretion (ADME) of drugs.
    • Pharmacodynamics studies how drugs exert their effects on the body.

    Drug Distribution and Adverse Effects

    • Organs with rapid drug distribution include the heart and liver.
    • Science of adverse drug effects on living organisms is called toxicology.
    • First-pass effect describes the large proportion of a drug metabolized into inactive metabolites by the liver.
    • Half-life indicates the time required for half of a drug to be eliminated from the body.

    Therapy Types and Drug Levels

    • Chronic illness treatment typically involves maintenance therapy.
    • Preventive therapy is designed to avoid illness and undesirable outcomes during planned medical events.
    • Peak level refers to the highest concentration of a drug in the bloodstream.
    • Unpredictable reactions occurring in a small percentage of patients are classified as idiosyncratic reactions.

    Supplemental and Toxicity Considerations

    • An example of supplemental therapy is administering oxygen to patients with respiratory issues.
    • Therapeutic index refers to the range between effective and toxic drug levels.
    • Trough level indicates the lowest concentration of a drug in the bloodstream.

    Palliative Care and Reactions

    • Palliative care focuses on comfort, pain relief, and support for patients and families during end-stage illness when curative treatments fail.
    • Stevens-Johnson Syndrome represents a severe hypersensitivity reaction to drugs.

    Additional Considerations

    • Understanding the generic name of medications is crucial for clinical practice.
    • First drug in a classification is known as a prototype drug.
    • Drugs are categorized into classifications based on similar pharmacological properties, like mechanism of action and therapeutic use.
    • Beta blockers are classified under antihypertensive medications.

    Pharmacodynamics and Drug Dissolution

    • Dissolution of solid dosage forms affects their absorption into the body.
    • Drugs preferentially distribute to areas with extensive blood supply first, such as the liver and kidneys.
    • The primary organ responsible for drug excretion is the kidneys.
    • The study of plant and animal-derived substances contributing to drug development is termed pharmacognosy.
    • Bioavailability refers to the fraction of administered drug that reaches systemic circulation after metabolism.

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    Description

    Test your knowledge of medication classification and dosage forms. Learn about prototypical drugs, drug classifications based on structure and therapeutic use, and the dissolution of solid dosage forms and their absorption.

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