Podcast
Questions and Answers
Where does medication absorption occur for oral drugs?
Where does medication absorption occur for oral drugs?
What happens to drugs in the liver during the first pass effect?
What happens to drugs in the liver during the first pass effect?
Which route of administration bypasses absorption in the GI tract?
Which route of administration bypasses absorption in the GI tract?
Where does the remaining amount of active drug go after leaving the liver?
Where does the remaining amount of active drug go after leaving the liver?
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What happens to drugs in the stomach during absorption?
What happens to drugs in the stomach during absorption?
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Study Notes
Medication Absorption and Distribution
- Medication absorption for oral drugs occurs in the gastrointestinal (GI) tract.
- During the first pass effect, the liver breaks down a significant amount of the drug, reducing its bioavailability.
- The intravenous (IV) route of administration bypasses absorption in the GI tract.
- After leaving the liver, the remaining amount of active drug enters the systemic circulation, where it is distributed to the rest of the body.
- In the stomach, drugs are mixed with stomach acid and digestive enzymes, which can affect their absorption, and may also undergo some chemical degradation.
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Description
Test your knowledge on medication absorption and learn about the process of drugs entering the bloodstream from their site of administration. Explore the different pathways of absorption, including the stomach and small intestine, and understand how oral drugs dissolve and pass through cell membranes.
