Podcast
Questions and Answers
What was the primary purpose of establishing Medicare?
What was the primary purpose of establishing Medicare?
Which additional groups were covered under Medicare by 2001?
Which additional groups were covered under Medicare by 2001?
What is the financing source for Medicare Part A?
What is the financing source for Medicare Part A?
How long must individuals contribute payroll taxes to qualify for Medicare?
How long must individuals contribute payroll taxes to qualify for Medicare?
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Which Medicare part covers outpatient services and physician visits?
Which Medicare part covers outpatient services and physician visits?
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What is the deductible amount for Medicare Part A in 2024?
What is the deductible amount for Medicare Part A in 2024?
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Which services are covered by Medicare Part A?
Which services are covered by Medicare Part A?
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What type of insurance is Medicare categorized under?
What type of insurance is Medicare categorized under?
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What is a common disadvantage of chemotherapy agents regarding their economic assessment?
What is a common disadvantage of chemotherapy agents regarding their economic assessment?
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In cost utility analysis (CUA), what is the outcome measurement unit?
In cost utility analysis (CUA), what is the outcome measurement unit?
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What does cost effectiveness analysis (CEA) primarily measure?
What does cost effectiveness analysis (CEA) primarily measure?
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Which pharmacoeconomic analysis focuses exclusively on financial aspects without considering patient outcomes?
Which pharmacoeconomic analysis focuses exclusively on financial aspects without considering patient outcomes?
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Which of the following is NOT a characteristic of cost benefit analysis (CBA)?
Which of the following is NOT a characteristic of cost benefit analysis (CBA)?
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What type of analysis involves assessing two chemotherapy regimens for non-small cell lung cancer?
What type of analysis involves assessing two chemotherapy regimens for non-small cell lung cancer?
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Which pharmacoeconomic study type is primarily concerned with the comparison of costs when outcomes are assumed equal?
Which pharmacoeconomic study type is primarily concerned with the comparison of costs when outcomes are assumed equal?
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What is the primary unit of comparison within cost utility analysis?
What is the primary unit of comparison within cost utility analysis?
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What was the Medicare Advantage program created through?
What was the Medicare Advantage program created through?
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What type of plans can administer Medicare Advantage?
What type of plans can administer Medicare Advantage?
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Which of the following is NOT a type of plan included in Medicare Advantage?
Which of the following is NOT a type of plan included in Medicare Advantage?
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What does a Medicare Advantage plan include if it has Part D benefits?
What does a Medicare Advantage plan include if it has Part D benefits?
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During which period can beneficiaries enroll in Part C services?
During which period can beneficiaries enroll in Part C services?
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What role does the healthcare team play in outpatient clinics concerning Medicare?
What role does the healthcare team play in outpatient clinics concerning Medicare?
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For what purpose does a pharmacy utilize Medicare information?
For what purpose does a pharmacy utilize Medicare information?
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Which of the following is included in the comprehensive coverage of Medicare Advantage?
Which of the following is included in the comprehensive coverage of Medicare Advantage?
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What is categorized as direct medical costs in pharmacoeconomic studies?
What is categorized as direct medical costs in pharmacoeconomic studies?
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Which type of cost relates to loss of productivity due to illness?
Which type of cost relates to loss of productivity due to illness?
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What is the purpose of timing adjustments in pharmacoeconomic studies?
What is the purpose of timing adjustments in pharmacoeconomic studies?
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Which formula would you use to calculate the present value of costs?
Which formula would you use to calculate the present value of costs?
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Which of the following is NOT a type of direct medical cost?
Which of the following is NOT a type of direct medical cost?
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In pharmacoeconomics, what do intangible costs represent?
In pharmacoeconomics, what do intangible costs represent?
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What is the main focus of pharmacoeconomics?
What is the main focus of pharmacoeconomics?
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What triggers a beneficiary to enter the catastrophic coverage phase in Medicare?
What triggers a beneficiary to enter the catastrophic coverage phase in Medicare?
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What does ACER stand for in pharmacoeconomic evaluations?
What does ACER stand for in pharmacoeconomic evaluations?
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How many tiers of coverage are commonly found in Medicare PDP drug formularies?
How many tiers of coverage are commonly found in Medicare PDP drug formularies?
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Which of the following costs are excluded from direct medical costs?
Which of the following costs are excluded from direct medical costs?
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Aside from direct medical costs, which costs should researchers consider when evaluating the impact of treating patients with certain diseases?
Aside from direct medical costs, which costs should researchers consider when evaluating the impact of treating patients with certain diseases?
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Who is responsible for approving medications for inclusion in the drug formulary?
Who is responsible for approving medications for inclusion in the drug formulary?
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What is the best perspective for pharmacoeconomic studies according to current economic theory?
What is the best perspective for pharmacoeconomic studies according to current economic theory?
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What is the purpose of the Pharmacy & Therapeutics (P&T) Committee in Medicare?
What is the purpose of the Pharmacy & Therapeutics (P&T) Committee in Medicare?
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When must the initial formulary draft be submitted to CMS?
When must the initial formulary draft be submitted to CMS?
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When estimating costs based on data collected more than one year prior or extending more than one year into the future, what should researchers do?
When estimating costs based on data collected more than one year prior or extending more than one year into the future, what should researchers do?
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What is the final decision period for the Pharmacy & Therapeutics Committee regarding new drugs?
What is the final decision period for the Pharmacy & Therapeutics Committee regarding new drugs?
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Which of the following best describes the most common perspective in pharmacoeconomic studies?
Which of the following best describes the most common perspective in pharmacoeconomic studies?
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What components are included in societal costs?
What components are included in societal costs?
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What must be done before the annual open enrollment period regarding the formulary?
What must be done before the annual open enrollment period regarding the formulary?
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Which of the following is an example of patient and family costs?
Which of the following is an example of patient and family costs?
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Which of the following best describes the structure of the most common Medicare PDP drug formulary?
Which of the following best describes the structure of the most common Medicare PDP drug formulary?
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Why are societal costs rarely used in pharmacoeconomic studies?
Why are societal costs rarely used in pharmacoeconomic studies?
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Study Notes
Pharmacoeconomics
- The description and analysis of drug therapy costs to healthcare systems and society.
- Also identifies, measures, and compares costs and consequences of pharmaceutical products/services.
Objectives
- Define pharmacoeconomics.
- Discuss the importance and clinical relevance of pharmacoeconomics to the practice of pharmacy and optimal provision of quality healthcare.
- Identify common examples for the three (3) types of outcomes evaluated in pharmacoeconomic studies.
- Clinical outcomes: Results of treatment with a drug (e.g., prevention, cure, adverse effects, toxicity).
- Economical outcomes: Costs associated with a therapy (e.g., labor, equipment, monitoring).
- Humanistic outcomes: Involves patients' point of view (e.g., patients' feelings and perceptions).
- Identify and discuss the general characteristics of the four (4) most common pharmacoeconomic study types.
- Cost minimization analysis (CMA)
- Cost benefit analysis (CBA)
- Cost effectiveness analysis (CEA)
- Cost utility analysis (CUA)
Types of Pharmacoeconomic Studies
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Cost minimization analysis (CMA):
- Costs are measured in dollars.
- Outcomes are assumed to be equivalent.
- Examples include comparing therapeutically equivalent medications (e.g., glipizide and glyburide) or inpatient versus outpatient use of a medication.
- Advantages: Simple study.
- Disadvantages: Outcomes must be assumed equivalent.
-
Cost benefit analysis (CBA):
- Measures both costs and outcomes in dollars.
- Advantages: Allows assessment of whether benefits exceed costs. Provides comparison of multiple products/services with varied outcomes.
- Disadvantages: Difficult to assign a monetary value to all health outcomes.
- Example: Costs (inputs) of implementing a PK consulting or diabetes clinic vs. cost savings (outcomes) associated with the service.
-
Cost effectiveness analysis (CEA):
- Measures costs in dollars ($) & outcomes in natural units (e.g., symptom-free days, mmHg, lives saved).
- Advantages: Outcomes easier to quantify since health units are commonly used.
- Disadvantages: Alternatives for comparison must have outcomes in the same units.
- Example: BCBS-MS assesses the addition of a new blood glucose-lowering medication to its preferred formulary, but the daily dose of the new medication is more expensive.
-
Cost utility analysis (CUA):
- Measures costs in dollars ($) and outcomes in health utilities, such as quality-adjusted life years (QALYs).
- Advantages: Different health outcomes can be compared as a common unit (QALYs) without assigning monetary values. Used when morbidity and mortality are key factors.
- Disadvantages: Difficult to determine an accurate QALY value.
- Example: Assessing costs and utilities of two common chemotherapy regimens for non-small cell lung cancer.
Importance of Pharmacoeconomics
- Increasing healthcare costs (e.g., $3.8 trillion in 2019, with $11,582 per person average)
- 17.7% of gross domestic product (GDP) in the USA
- $369.7 billion spent on prescription medications.
Benefits of Pharmacoeconomics
- Doing more with fewer resources (e.g., $$$, labor).
- Provides data to make important decisions related to healthcare.
- Appropriate drug selection for hospital or insurance formulary.
- Management strategies for certain disease states (e.g., guideline development).
- Appropriate drug selection to treat patients' medical conditions.
- Implementation of new services within a pharmacy, hospital, or clinic (e.g., MTM (medication therapy management), PK consulting, DSME (diabetes self-management education)).
Case Studies
- Multiple case studies assessing cost-effectiveness for treating obesity or other diseases using pharmacoeconomic methods are presented.
- The studies presented varied in their methods, outcomes, and populations examined.
- Key statistics and findings extracted from the presented case studies are available.
Healthcare Provider & Payer Considerations
- Healthcare providers aim to deliver optimal patient care and ensure patients achieve the best possible treatment results, considering various factors (e.g., demographics, clinical, social and economic).
- Insurance payers strive to contain rising costs by properly assessing treatment costs alongside safety, efficacy, and effectiveness of treatment options.
- Pharmacoeconomics assists both providers and payers in estimating benefits and the value of patient outcomes in relation to cost for medications and healthcare products/services.
Why Pharmacoeconomics?
- Individual patients: Healthcare providers can use appropriate demographic, clinical, social, and economic factors when choosing the best medication and care plan.
- Community level: Administrators assess costs and value when implementing a new service at a hospital or pharmacy.
- Includes factors like profitability, improved patient outcomes, and improved quality of care.
- Population level: Interprofessional teams work to determine the most efficient and effective therapies for various patient populations. Includes development of specific drug formularies and considerations for patient copays and costs.
Medicare Part D Prescription Drug Tiers:
- Tier 1: Covers generic prescription drugs, with the lowest copay.
- Tier 2: Covers preferred brand-name prescription drugs, with a medium level copay.
- Tier 3: Covers non-preferred brand-name prescription drugs, with a higher level copay.
- Specialty Tier: High-cost specialty drugs with a high copay.
Types of Pharmacoeconomic Studies
-
Summary table
- Type of study, Cost Measurement Unit & Outcome Measurement Unit.
Cost-Minimization Analysis (CMA)
- Example Case Study:
- Comparing two generic drugs (e.g. metformin in different brands)
- Comparing different antibiotics for pneumonia
- Comparing once-daily versus every 8 hours dosing for an aminoglycoside
- Description and discussion of cost minimization, including advantages and disadvantages of the method.
Midterm & Final Exam Review Materials
- A comprehensive review of all topics covered in PHA 746 lectures.
- Information regarding the format, topics, and resources for the mid-term and final examinations.
Advanced Modeling
- Discussion of both decision analysis and Markov modeling, including advantages and disadvantages for each model.
- Study steps necessary for both decision analysis and Markov modeling methods.
HRQoL Measures
- Describes different types and methods of measuring health outcomes, including utility measures, quality-of-life measures (HRQoL), preference-based classification systems, and patient-reported outcomes (PROs) and the advantages and disadvantages.
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Description
Test your knowledge on the Medicare system, its coverage, and financing. This quiz also explores pharmacoeconomic concepts like cost utility and cost effectiveness analyses. See how well you understand these critical components of healthcare economics.