Podcast
Questions and Answers
A previously healthy 39-year-old woman at 37 weeks' gestation comes to the emergency department 2 hours after the onset of acute pain in the left hemithorax. She says that the pain is exacerbated by breathing. Her temperature is $38.2°C$ ($100.8°F$), pulse is 120/min, respirations are 24/min, and blood pressure is 110/70 mm Hg. Fetal heart tones are 170/min. Examination shows no abnormalities. An x-ray of the chest shows no abnormalities. An ECG shows nonspecific changes. Arterial blood gas analysis on room air shows:
$pH = 7.43$
$Pco_2 = 35 mm Hg$
$P0_2 = 70 mm Hg$
Which of the following is the most likely diagnosis?
A previously healthy 39-year-old woman at 37 weeks' gestation comes to the emergency department 2 hours after the onset of acute pain in the left hemithorax. She says that the pain is exacerbated by breathing. Her temperature is $38.2°C$ ($100.8°F$), pulse is 120/min, respirations are 24/min, and blood pressure is 110/70 mm Hg. Fetal heart tones are 170/min. Examination shows no abnormalities. An x-ray of the chest shows no abnormalities. An ECG shows nonspecific changes. Arterial blood gas analysis on room air shows: $pH = 7.43$ $Pco_2 = 35 mm Hg$ $P0_2 = 70 mm Hg$ Which of the following is the most likely diagnosis?
- Pulmonary embolus (correct)
- Angina pectoris
- Viral pneumonia
- Myocardial infarction
- Costochondritis
A 52-year-old woman comes to the physician for a routine examination. She has mild hypothyroidism well controlled with levothyroxine. Five years ago, she was diagnosed with stage I breast cancer; she completed tamoxifen therapy 1 year ago and is currently in remission. Menopause occurred 4 years ago. Her mother sustained a femoral fracture in a bicycle collision at the age of 55 years. The patient has smoked two cigarettes weekly for 25 years. She is 150 cm (4 ft 11 in) tall and weighs 43 kg (95 lb); BMI is 19 kg/m². Examination shows no thyromegaly. There is a small, well-healed surgical scar over the upper outer quadrant of the left breast. The remainder of the breast and pelvic examinations show no abnormalities. Which of the following historical findings is the greatest risk factor for osteoporotic fracture in this patient?
A 52-year-old woman comes to the physician for a routine examination. She has mild hypothyroidism well controlled with levothyroxine. Five years ago, she was diagnosed with stage I breast cancer; she completed tamoxifen therapy 1 year ago and is currently in remission. Menopause occurred 4 years ago. Her mother sustained a femoral fracture in a bicycle collision at the age of 55 years. The patient has smoked two cigarettes weekly for 25 years. She is 150 cm (4 ft 11 in) tall and weighs 43 kg (95 lb); BMI is 19 kg/m². Examination shows no thyromegaly. There is a small, well-healed surgical scar over the upper outer quadrant of the left breast. The remainder of the breast and pelvic examinations show no abnormalities. Which of the following historical findings is the greatest risk factor for osteoporotic fracture in this patient?
- BMI
- Levothyroxine therapy
- Tobacco use
- Tamoxifen therapy
- Family history of fracture (correct)
A 20-year-old woman comes to the physician because of a 1-week history of vaginal discharge. She is sexually active with one partner, and they use condoms inconsistently. She reports that he was recently treated for syphilis. Physical examination of the patient shows no abnormalities. Pelvic examination shows white verrucous lesions over the upper vaginal wall and cervix. A Pap smear is reported as atypical squamous cells. Human papillomavirus testing is negative for high-risk types. Which of the following is the most likely diagnosis?
A 20-year-old woman comes to the physician because of a 1-week history of vaginal discharge. She is sexually active with one partner, and they use condoms inconsistently. She reports that he was recently treated for syphilis. Physical examination of the patient shows no abnormalities. Pelvic examination shows white verrucous lesions over the upper vaginal wall and cervix. A Pap smear is reported as atypical squamous cells. Human papillomavirus testing is negative for high-risk types. Which of the following is the most likely diagnosis?
- Condylomata acuminata (correct)
- Herpes simplex
- Cervical intraepithelial neoplasia (CIN) 2
- Secondary syphilis
- Bacterial vaginosis
A 25-year-old woman comes to the physician because of a 4-week history of right-sided pelvic pain. She has been sexually active with one partner for 3 years; they use condoms for contraception. Her last menstrual period was 3 weeks ago. She is afebrile. Pelvic examination shows a 12-cm, cystic, mobile, right adnexal mass. Her serum CA 125 concentration is 35 U/mL (N<35). Serum β-hCG testing is negative. An x-ray of the abdomen shows calcium deposits in the mass. Which of the following is the most likely diagnosis?
A 25-year-old woman comes to the physician because of a 4-week history of right-sided pelvic pain. She has been sexually active with one partner for 3 years; they use condoms for contraception. Her last menstrual period was 3 weeks ago. She is afebrile. Pelvic examination shows a 12-cm, cystic, mobile, right adnexal mass. Her serum CA 125 concentration is 35 U/mL (N<35). Serum β-hCG testing is negative. An x-ray of the abdomen shows calcium deposits in the mass. Which of the following is the most likely diagnosis?
Five weeks after the uncomplicated delivery of her newborn, a 25-year-old woman, gravida 1, para 1, comes to the physician with concerns about insomnia, restlessness, extreme fatigue, irritability, and depression. She has not been eating well. She finds the baby's crying increasingly annoying and has been letting him cry alone in the crib for long periods of time. She is having difficulty with her memory and ability to concentrate. While her husband has been supportive, she has had difficulty involving him in the care of the baby. She is afraid that she may hurt her child and says that maybe she would be better off dead. Which of the following is the most appropriate initial step in management?
Five weeks after the uncomplicated delivery of her newborn, a 25-year-old woman, gravida 1, para 1, comes to the physician with concerns about insomnia, restlessness, extreme fatigue, irritability, and depression. She has not been eating well. She finds the baby's crying increasingly annoying and has been letting him cry alone in the crib for long periods of time. She is having difficulty with her memory and ability to concentrate. While her husband has been supportive, she has had difficulty involving him in the care of the baby. She is afraid that she may hurt her child and says that maybe she would be better off dead. Which of the following is the most appropriate initial step in management?
A 36-year-old woman, gravida 1, para 1, has been unable to conceive for 1 year. Her vaginal delivery 2 years ago was complicated by postpartum hemorrhage and endometritis treated with dilatation and curettage. She has not resumed menses since delivery but does have cyclic abdominal pain. Examination shows normal findings. Her husband's semen analysis shows normal findings. Which of the following is the most likely cause?
A 36-year-old woman, gravida 1, para 1, has been unable to conceive for 1 year. Her vaginal delivery 2 years ago was complicated by postpartum hemorrhage and endometritis treated with dilatation and curettage. She has not resumed menses since delivery but does have cyclic abdominal pain. Examination shows normal findings. Her husband's semen analysis shows normal findings. Which of the following is the most likely cause?
A 32-year-old woman, gravida 2, para 1, at 27 weeks' gestation is brought to the emergency department because of a 3-hour history of painful contractions every 5 minutes. She has not had vaginal discharge or itching. During her first prenatal visit, routine urine culture grew 10,000 colonies/mL of Streptococcus agalactiae (group B). She was not treated at that time because she was asymptomatic. She has no history of serious illness. Pregnancy had been otherwise uncomplicated. She takes no medications and has an allergy to penicillin. Her first pregnancy ended in spontaneous vaginal delivery at 33 weeks' gestation. Her temperature is $37.8°C$ ($100°F$), pulse is 100/min, and blood pressure is 90/50 mm Hg. Abdominal examination shows tenderness to percussion over the right flank. The uterus is nontender and consistent in size with a 27-week gestation. The fetal heart rate is 160/min. Uterine contractions occur every 5 minutes and last 45 seconds. On pelvic examination, the cervix is 2 cm dilated and 75% effaced; the vertex is at 0 station. Which of the following is the most likely cause of this patient's symptoms?
A 32-year-old woman, gravida 2, para 1, at 27 weeks' gestation is brought to the emergency department because of a 3-hour history of painful contractions every 5 minutes. She has not had vaginal discharge or itching. During her first prenatal visit, routine urine culture grew 10,000 colonies/mL of Streptococcus agalactiae (group B). She was not treated at that time because she was asymptomatic. She has no history of serious illness. Pregnancy had been otherwise uncomplicated. She takes no medications and has an allergy to penicillin. Her first pregnancy ended in spontaneous vaginal delivery at 33 weeks' gestation. Her temperature is $37.8°C$ ($100°F$), pulse is 100/min, and blood pressure is 90/50 mm Hg. Abdominal examination shows tenderness to percussion over the right flank. The uterus is nontender and consistent in size with a 27-week gestation. The fetal heart rate is 160/min. Uterine contractions occur every 5 minutes and last 45 seconds. On pelvic examination, the cervix is 2 cm dilated and 75% effaced; the vertex is at 0 station. Which of the following is the most likely cause of this patient's symptoms?
A 22-year-old woman, gravida 2, para 1, at 38 weeks' gestation comes to the physician for a routine prenatal visit. She feels well other than intermittent, mild, low back pain, and her pregnancy has been uncomplicated. Her pulse is 100/min, and blood pressure is 130/90 mm Hg. Physical examination shows no abnormalities. The estimated fetal weight is 3629 g (8 lb). The fetal heart rate is 120/min. The cervix is 4 cm dilated and 100% effaced; the vertex is at -1 station. Which of the following is the most likely cause of these findings?
A 22-year-old woman, gravida 2, para 1, at 38 weeks' gestation comes to the physician for a routine prenatal visit. She feels well other than intermittent, mild, low back pain, and her pregnancy has been uncomplicated. Her pulse is 100/min, and blood pressure is 130/90 mm Hg. Physical examination shows no abnormalities. The estimated fetal weight is 3629 g (8 lb). The fetal heart rate is 120/min. The cervix is 4 cm dilated and 100% effaced; the vertex is at -1 station. Which of the following is the most likely cause of these findings?
A 15-year-old girl is brought to the physician because of a 3-day history of fever, abdominal pain, and nausea. She also has had a thick, white vaginal discharge. Menarche was at the age of 13 years, and her menses occur at irregular 28- to 40-day intervals. She became sexually active 1 month ago and uses condoms inconsistently. Her temperature is $39.6°C$ ($103.2°F$), pulse is 108/min, respirations are 20/min, and blood pressure is 102/80 mm Hg. Examination shows lower abdominal tenderness. Pelvic examination shows pain with cervical motion and adnexal tenderness with a 3-cm mass. A Gram stain of vaginal discharge shows gram-negative diplococci. Which of the following is the most likely explanation for this patient's susceptibility to this condition?
A 15-year-old girl is brought to the physician because of a 3-day history of fever, abdominal pain, and nausea. She also has had a thick, white vaginal discharge. Menarche was at the age of 13 years, and her menses occur at irregular 28- to 40-day intervals. She became sexually active 1 month ago and uses condoms inconsistently. Her temperature is $39.6°C$ ($103.2°F$), pulse is 108/min, respirations are 20/min, and blood pressure is 102/80 mm Hg. Examination shows lower abdominal tenderness. Pelvic examination shows pain with cervical motion and adnexal tenderness with a 3-cm mass. A Gram stain of vaginal discharge shows gram-negative diplococci. Which of the following is the most likely explanation for this patient's susceptibility to this condition?
A previously healthy 5-year-old girl is brought to the physician because of a 2-day history of a foul-smelling, yellow discharge and vaginal spotting on her underpants. She has not had pain with urination. Physical examination shows no abnormalities. Pelvic examination shows mild vulvar erythema and a purulent discharge at the vaginal opening. Which of the following is the most likely cause?
A previously healthy 5-year-old girl is brought to the physician because of a 2-day history of a foul-smelling, yellow discharge and vaginal spotting on her underpants. She has not had pain with urination. Physical examination shows no abnormalities. Pelvic examination shows mild vulvar erythema and a purulent discharge at the vaginal opening. Which of the following is the most likely cause?
A moderately obese 27-year-old woman, gravida 1, para 1, comes to the physician because of pain and tenderness in her left thigh for 2 days. She delivered a healthy newborn at term 6 days ago. Examination shows tenderness and swelling over the left thigh and calf. There is pain in the left calf with dorsiflexion of the left foot. Which of the following is the most appropriate next step to confirm the diagnosis?
A moderately obese 27-year-old woman, gravida 1, para 1, comes to the physician because of pain and tenderness in her left thigh for 2 days. She delivered a healthy newborn at term 6 days ago. Examination shows tenderness and swelling over the left thigh and calf. There is pain in the left calf with dorsiflexion of the left foot. Which of the following is the most appropriate next step to confirm the diagnosis?
A 21-year-old primigravid woman at 8 weeks' gestation comes to the physician for her first prenatal visit. She has sickle cell disease and is concerned about the risk for transmitting this disease to her fetus. Her pregnancy has been otherwise uncomplicated. Examination shows a uterus consistent in size with an 8-week gestation. Her husband's hemoglobin electrophoresis shows:
Hemoglobin A 42% (N=95%-98%)
Hemoglobin A2 3% (N=2%-3%)
Hemoglobin F 2% (N=0.8%-2%)
Hemoglobin S 53% (N=0%)
This patient should be counseled that the probability her fetus will have sickle cell disease is closest to which of the following?
A 21-year-old primigravid woman at 8 weeks' gestation comes to the physician for her first prenatal visit. She has sickle cell disease and is concerned about the risk for transmitting this disease to her fetus. Her pregnancy has been otherwise uncomplicated. Examination shows a uterus consistent in size with an 8-week gestation. Her husband's hemoglobin electrophoresis shows: Hemoglobin A 42% (N=95%-98%) Hemoglobin A2 3% (N=2%-3%) Hemoglobin F 2% (N=0.8%-2%) Hemoglobin S 53% (N=0%) This patient should be counseled that the probability her fetus will have sickle cell disease is closest to which of the following?
A 37-year-old primigravid woman at 35 weeks' gestation comes to the physician for a routine prenatal visit. She has been receiving routine prenatal care since 8 weeks' gestation. Pregnancy has been complicated by the onset of hypertension at 18 weeks' gestation that has been well controlled with labetalol. She has an 18-year history of type 1 diabetes mellitus. Her hemoglobin A1c at 8 weeks' gestation was 5.7%. Her blood pressure now is 140/90 mm Hg. Examination shows a soft uterus with a fundal height of 32 cm. The fetal heart rate is 140/min. Serum studies show a urea nitrogen concentration of 8 mg/dL and creatinine concentration of 1 mg/dL. A 24-hour urine collection shows a protein concentration of 800 mg. Ultrasonography shows a normal fetus at the 5th percentile for weight; the placenta is anterior and fundal. There is a mild decrease in the amount of amniotic fluid. Which of the following is the most likely cause of the ultrasound findings?
A 37-year-old primigravid woman at 35 weeks' gestation comes to the physician for a routine prenatal visit. She has been receiving routine prenatal care since 8 weeks' gestation. Pregnancy has been complicated by the onset of hypertension at 18 weeks' gestation that has been well controlled with labetalol. She has an 18-year history of type 1 diabetes mellitus. Her hemoglobin A1c at 8 weeks' gestation was 5.7%. Her blood pressure now is 140/90 mm Hg. Examination shows a soft uterus with a fundal height of 32 cm. The fetal heart rate is 140/min. Serum studies show a urea nitrogen concentration of 8 mg/dL and creatinine concentration of 1 mg/dL. A 24-hour urine collection shows a protein concentration of 800 mg. Ultrasonography shows a normal fetus at the 5th percentile for weight; the placenta is anterior and fundal. There is a mild decrease in the amount of amniotic fluid. Which of the following is the most likely cause of the ultrasound findings?
A 57-year-old woman, gravida 3, para 3, comes to the physician because of loss of urine for 2 weeks. She now wears an absorbent pad constantly and frequently soaks the pad. All of her children were delivered vaginally with no complications. Three years ago, she received radiation therapy for cervical cancer and has been cancer free since then. She has no other history of serious illness and takes no medications. Vital signs are within normal limits. Physical examination shows no abnormalities. Genitourinary examination shows thin, atrophic, moist vaginal mucosa; there is a pool of fluid in the vaginal canal. Her postvoid residual volume is less than 10 mL. Urinalysis shows no abnormalities. Which of the following is the most likely diagnosis?
A 57-year-old woman, gravida 3, para 3, comes to the physician because of loss of urine for 2 weeks. She now wears an absorbent pad constantly and frequently soaks the pad. All of her children were delivered vaginally with no complications. Three years ago, she received radiation therapy for cervical cancer and has been cancer free since then. She has no other history of serious illness and takes no medications. Vital signs are within normal limits. Physical examination shows no abnormalities. Genitourinary examination shows thin, atrophic, moist vaginal mucosa; there is a pool of fluid in the vaginal canal. Her postvoid residual volume is less than 10 mL. Urinalysis shows no abnormalities. Which of the following is the most likely diagnosis?
A 57-year-old woman, gravida 6, para 6, comes to the physician because of a 6-month history of immediate loss of urine when she coughs or exercises. Her children were born by vaginal delivery. Her last menstrual period was 10 years ago, and she has never received estrogen therapy. Pelvic examination shows a normal-sized uterus and ovaries. There is downward mobility of the urethral vesical junction with Valsalva maneuver. Which of the following is the most likely diagnosis?
A 57-year-old woman, gravida 6, para 6, comes to the physician because of a 6-month history of immediate loss of urine when she coughs or exercises. Her children were born by vaginal delivery. Her last menstrual period was 10 years ago, and she has never received estrogen therapy. Pelvic examination shows a normal-sized uterus and ovaries. There is downward mobility of the urethral vesical junction with Valsalva maneuver. Which of the following is the most likely diagnosis?
A 15-year-old girl is brought to the physician because of a 1-week history of constant severe abdominal pain. During the past year, she has had 10 episodes of cramps; each episode lasts 3 to 5 days. She has no history of serious illness and takes no medications. She has never had a menstrual period. She is sexually active with one male partner, and they do not use contraception. She is at the 80th percentile for height and weight. Her temperature is $37.8°C$ ($100°F$), pulse is 120/min, respirations are 16/min, and blood pressure is 90/50 mm Hg. Breast and genital development is Tanner stage 5. Abdominal examination shows moderate tenderness. A mass is palpated in the suprapubic region at the midline. Pelvic examination shows normal-appearing external genitalia and lower vagina. The cervix cannot be visualized because of bluish bulging vaginal tissue that obscures the upper vagina. Which of the following is the most appropriate next step in management?
A 15-year-old girl is brought to the physician because of a 1-week history of constant severe abdominal pain. During the past year, she has had 10 episodes of cramps; each episode lasts 3 to 5 days. She has no history of serious illness and takes no medications. She has never had a menstrual period. She is sexually active with one male partner, and they do not use contraception. She is at the 80th percentile for height and weight. Her temperature is $37.8°C$ ($100°F$), pulse is 120/min, respirations are 16/min, and blood pressure is 90/50 mm Hg. Breast and genital development is Tanner stage 5. Abdominal examination shows moderate tenderness. A mass is palpated in the suprapubic region at the midline. Pelvic examination shows normal-appearing external genitalia and lower vagina. The cervix cannot be visualized because of bluish bulging vaginal tissue that obscures the upper vagina. Which of the following is the most appropriate next step in management?
A 27-year-old woman who is a long-distance runner comes to the physician because of a 1-month history of postcoital spotting lasting 1 to 2 days. Menses have occurred at regular intervals since menarche at the age of 14 years. She underwent a bilateral tubal ligation 9 months ago. She is sexually active with a new partner. Which of the following is the most likely diagnosis?
A 27-year-old woman who is a long-distance runner comes to the physician because of a 1-month history of postcoital spotting lasting 1 to 2 days. Menses have occurred at regular intervals since menarche at the age of 14 years. She underwent a bilateral tubal ligation 9 months ago. She is sexually active with a new partner. Which of the following is the most likely diagnosis?
A 32-year-old woman comes to the physician because of a 3-year history of increasingly irregular menses. Menses had occurred at irregular 45- to 60-day intervals since menarche at the age of 14 years, but now her cycle interval is up to 90 days. Her menstrual periods typically last 2 to 7 days. She is otherwise asymptomatic and has no history of serious illness. She is 163 cm (5 ft 4 in) tall and weighs 103 kg (227 lb); BMI is 39 kg/m². Her pulse is 80/min, and blood pressure is 140/80 mm Hg. Physical examination shows velvety pigmented skin over the axillae and groin. Which of the following serum hormone concentrations is most likely to be increased in this patient?
A 32-year-old woman comes to the physician because of a 3-year history of increasingly irregular menses. Menses had occurred at irregular 45- to 60-day intervals since menarche at the age of 14 years, but now her cycle interval is up to 90 days. Her menstrual periods typically last 2 to 7 days. She is otherwise asymptomatic and has no history of serious illness. She is 163 cm (5 ft 4 in) tall and weighs 103 kg (227 lb); BMI is 39 kg/m². Her pulse is 80/min, and blood pressure is 140/80 mm Hg. Physical examination shows velvety pigmented skin over the axillae and groin. Which of the following serum hormone concentrations is most likely to be increased in this patient?
A 27-year-old woman, gravida 2, para 1, aborta 1, comes to the physician because of a 3-day history of increasing abdominal pain and a 1-day history of fever. Five days ago, she underwent an uncomplicated abortion at 10 weeks' gestation and received prophylactic antibiotics. Her temperature is $39.2°C$ ($102.6°F$), pulse is 110/min, respirations are 24/min, and blood pressure is 90/50 mm Hg. Physical examination shows a tender uterus consistent in size with a 12-week gestation and no adnexal masses. Pelvic ultrasonography shows a heterogeneous endometrial mass. After intravenous antibiotic therapy is started, she undergoes suction dilatation and curettage followed by sharp curettage to remove the infected material. This patient is at increased risk for which of the following conditions?
A 27-year-old woman, gravida 2, para 1, aborta 1, comes to the physician because of a 3-day history of increasing abdominal pain and a 1-day history of fever. Five days ago, she underwent an uncomplicated abortion at 10 weeks' gestation and received prophylactic antibiotics. Her temperature is $39.2°C$ ($102.6°F$), pulse is 110/min, respirations are 24/min, and blood pressure is 90/50 mm Hg. Physical examination shows a tender uterus consistent in size with a 12-week gestation and no adnexal masses. Pelvic ultrasonography shows a heterogeneous endometrial mass. After intravenous antibiotic therapy is started, she undergoes suction dilatation and curettage followed by sharp curettage to remove the infected material. This patient is at increased risk for which of the following conditions?
A 19-year-old woman comes to the emergency department because of moderate lower abdominal pain and vaginal spotting that began after her last menstrual period 2 weeks ago. Menses occur at regular 28-day intervals. She underwent a first trimester elective abortion 8 months ago and has been using an oral contraceptive since then. She has been sexually active with one male partner for 1 year. Her temperature is $37.6°C$ ($99.6°F$); other vital signs are within normal limits. Abdominal examination shows no tenderness. Pelvic examination shows blood-tinged discharge at the cervical os. There is cervical motion and mild uterine tenderness. A urine pregnancy test is negative. Which of the following is the most likely cause of this patient's symptoms?
A 19-year-old woman comes to the emergency department because of moderate lower abdominal pain and vaginal spotting that began after her last menstrual period 2 weeks ago. Menses occur at regular 28-day intervals. She underwent a first trimester elective abortion 8 months ago and has been using an oral contraceptive since then. She has been sexually active with one male partner for 1 year. Her temperature is $37.6°C$ ($99.6°F$); other vital signs are within normal limits. Abdominal examination shows no tenderness. Pelvic examination shows blood-tinged discharge at the cervical os. There is cervical motion and mild uterine tenderness. A urine pregnancy test is negative. Which of the following is the most likely cause of this patient's symptoms?
A 17-year-old primigravid patient comes to the physician because she has had decreased fetal movement over the past 2 days. She does not recall the date of her last menstrual period and has had only one previous prenatal visit. Examination shows a uterus consistent in size with a 32-week gestation. Ultrasonography shows a biparietal diameter consistent with a 31-week gestation. There is a duodenal bubble and flaccid tone of the fetus. Which of the following is the most likely cause of these findings?
A 17-year-old primigravid patient comes to the physician because she has had decreased fetal movement over the past 2 days. She does not recall the date of her last menstrual period and has had only one previous prenatal visit. Examination shows a uterus consistent in size with a 32-week gestation. Ultrasonography shows a biparietal diameter consistent with a 31-week gestation. There is a duodenal bubble and flaccid tone of the fetus. Which of the following is the most likely cause of these findings?
A 34-year-old woman, gravida 4, para 3, at 40 weeks' gestation is admitted because of a blood pressure of 160/95 mm Hg. She has chronic hypertension and is being treated with methyldopa. Ultrasonography shows fetal growth restriction. Four hours after induction of labor with oxytocin, the cervix is 6 cm dilated. A fetal heart tracing is shown. Which of the following is the most likely explanation for the findings shown in the fetal heart tracing?
A 34-year-old woman, gravida 4, para 3, at 40 weeks' gestation is admitted because of a blood pressure of 160/95 mm Hg. She has chronic hypertension and is being treated with methyldopa. Ultrasonography shows fetal growth restriction. Four hours after induction of labor with oxytocin, the cervix is 6 cm dilated. A fetal heart tracing is shown. Which of the following is the most likely explanation for the findings shown in the fetal heart tracing?
A 22-year-old woman comes to the physician because of a 2-week history of increasingly severe vaginal burning and discharge. She has been sexually active with one partner for 1 year, and they use condoms consistently for contraception. Examination shows normal external genitalia and a gray frothy vaginal discharge. The pH of the vaginal discharge is 5; microscopic examination shows squamous epithelial cells coated with bacteria. Which of the following is the most appropriate pharmacotherapy?
A 22-year-old woman comes to the physician because of a 2-week history of increasingly severe vaginal burning and discharge. She has been sexually active with one partner for 1 year, and they use condoms consistently for contraception. Examination shows normal external genitalia and a gray frothy vaginal discharge. The pH of the vaginal discharge is 5; microscopic examination shows squamous epithelial cells coated with bacteria. Which of the following is the most appropriate pharmacotherapy?
A 23-year-old primigravid woman at 33 weeks' gestation is admitted to the hospital because she has not felt fetal movement for 2 days. Pregnancy had been uncomplicated. She has no history of serious illness. Her sister has had three spontaneous abortions. The patient's temperature is $37°C$ ($98.6°F$), pulse is 80/min, and blood pressure is 110/60 mm Hg. Examination shows a soft uterus consistent in size with a 33-week gestation. Fundal height is 34 cm. Fetal heart tones cannot be auscultated. Ultrasonography confirms intrauterine fetal demise. Laboratory studies show the patient to be a homozygote for the factor $V$ Leiden mutation. Thrombosis of which of the following is the most likely cause of the fetal demise?
A 23-year-old primigravid woman at 33 weeks' gestation is admitted to the hospital because she has not felt fetal movement for 2 days. Pregnancy had been uncomplicated. She has no history of serious illness. Her sister has had three spontaneous abortions. The patient's temperature is $37°C$ ($98.6°F$), pulse is 80/min, and blood pressure is 110/60 mm Hg. Examination shows a soft uterus consistent in size with a 33-week gestation. Fundal height is 34 cm. Fetal heart tones cannot be auscultated. Ultrasonography confirms intrauterine fetal demise. Laboratory studies show the patient to be a homozygote for the factor $V$ Leiden mutation. Thrombosis of which of the following is the most likely cause of the fetal demise?
Flashcards
Acute Left Hemithorax Pain
Acute Left Hemithorax Pain
Symptoms in a 39-year-old woman at 37 weeks' gestation including pain, fever, and tachycardia, potentially indicating serious conditions like pulmonary embolism.
Fetal Heart Tones
Fetal Heart Tones
Fetal heart rate observed at 170/min in the pregnant patient, indicating fetal tachycardia.
Diagnosis for Chest Pain
Diagnosis for Chest Pain
The most likely diagnosis based on a pregnant woman's symptoms and lab findings is pulmonary embolus.
Risk Factors for Osteoporotic Fracture
Risk Factors for Osteoporotic Fracture
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Osteoporosis Risk Factors
Osteoporosis Risk Factors
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Vaginal Discharge in Young Woman
Vaginal Discharge in Young Woman
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White Verrucous Lesions
White Verrucous Lesions
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CA-125 Concentration
CA-125 Concentration
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Fetal Heart Rate Pattern
Fetal Heart Rate Pattern
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Contraception Effectiveness
Contraception Effectiveness
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Cesarean Delivery Complications
Cesarean Delivery Complications
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Pelvic Pain Diagnosis
Pelvic Pain Diagnosis
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Hypothyroidism and Bone Health
Hypothyroidism and Bone Health
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Tamoxifen Therapy
Tamoxifen Therapy
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Inconsistent Condom Use
Inconsistent Condom Use
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Pap Smear Result
Pap Smear Result
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Anticipated Clinical Findings
Anticipated Clinical Findings
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Chlamydia Trachomatis History
Chlamydia Trachomatis History
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Contraceptive Counseling
Contraceptive Counseling
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Right Occipitoposterior Position
Right Occipitoposterior Position
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Endometritis Symptoms
Endometritis Symptoms
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Pelvic Hemorrhage Signs
Pelvic Hemorrhage Signs
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Viral Pneumonia
Viral Pneumonia
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Tachycardia in Pregnant Patients
Tachycardia in Pregnant Patients
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Family History of Fractures
Family History of Fractures
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Study Notes
Medical Exam Questions and Answers
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Case 1: A 39-year-old pregnant woman presented with sudden left-sided chest pain.
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Patient's symptoms worsened with breathing.
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Vital signs: Temperature 38.2°C (100.8°F), pulse 120/min, respirations 24/min, blood pressure 110/70 mm Hg.
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Fetal heart tones 170/min.
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Chest x-ray and ECG normal.
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Arterial blood gas analysis: pH 7.43, PCO2 35 mm Hg, PO2 70 mm Hg.
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Most likely diagnosis: Costochondritis.
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Case 2: A 52-year-old woman with a history of breast cancer and hypothyroidism, presenting for a routine examination.
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Her BMI is 19 kg/m².
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Smoked two cigarettes weekly for 25 years
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Family history of fracture.
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Current medication is levothyroxine.
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Most likely greatest risk factor for osteoporotic fracture: Family history of fracture.
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Case 3: A 20-year-old woman with a 1-week history of vaginal discharge.
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Sexually active with one partner.
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Partner recently treated for syphilis.
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Physical examination normal.
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Pelvic examination showed white verrucous lesions on the upper vaginal wall and cervix.
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Pap smear reported as atypical squamous cells.
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HPV testing negative for high-risk types.
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Most likely diagnosis: Condylomata acuminata (genital warts).
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Case 4: A 25-year-old woman with 4-week history of right-sided pelvic pain.
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Sexual active for 3 years; using condoms.
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Last menstrual period 3 weeks prior.
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Afebrile.
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Pelvic examination revealed a 12-cm cystic, mobile, right adnexal mass.
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Normal serum CA 125 concentrations (<35 U/mL).
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Serum β-hCG negative.
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X-ray showed calcium deposits in the mass.
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Most likely diagnosis: Cystic teratoma (a type of ovarian tumor).
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Case 5: A 25-year-old woman, five weeks postpartum, presented with insomnia, restlessness, extreme fatigue, irritability, and depression.
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Difficulty involving husband in baby's care.
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Worried about hurting child and thoughts of harming herself.
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Most appropriate initial step in management: Arrange for an immediate psychiatric evaluation.
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Case 6: A 36-year-old woman with infertility for 1 year, presenting for infertility evaluation, was complicated by post-partum hemorrhage and endometritis treated with dilatation and curettage.
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Normal findings on examination.
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Husband shows normal semen analysis.
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Most likely cause: Tubal occlusion or uterine synechiae.
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Case 7: A 32-year-old pregnant woman with painful contractions every 5 minutes at 27 weeks' gestation. Her past pregnancy ended spontaneously at week 33.
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Recent urine culture positive for Streptococcus agalactiae (group B).
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Her temperature is 37.8°C (100°F), pulse is 100/min, and blood pressure is 90/50 mm Hg.
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On pelvic examination, the cervix is dilated 2 cm and 75% effaced, with vertex at 0 station.
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Most likely diagnosis: Chorioamnionitis (infection of the fetal membranes).
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Case 8: A 22-year-old woman at 38 weeks' gestation with mild, low back pain.
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Pulse 100/min and blood pressure 130/90 mm Hg.
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Physical examination normal.
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Estimated fetal weight 3629 g (8 lb).
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Cervical examination: 4 cm dilated, 100% effaced, vertex at –1 station, fetal heart rate 120/min.
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Most likely cause of findings: Normal labor.
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Case 9: A 15-year-old girl with fever, abdominal pain, and vaginal discharge.
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Recent sexual activity with inconsistent condom use and partner treated for syphilis.
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Lower abdominal tenderness, a 3-cm tender mass, and a Gram stain of vaginal discharge shows gram-negative diplococci.
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Most likely explanation for susceptibility: Immature immune system.
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Case 10: A 5-year-old girl with a foul-smelling vaginal discharge and vaginal spotting.
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No abnormalities on examination.
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Pelvic examination revealed mild vulvar erythema and purulent discharge at the vaginal opening.
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Most likely cause: Vaginal foreign body.
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Case 11: A 27-year-old woman with pain and tenderness in the left thigh.
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Recent delivery had a healthy newborn at term 6 days ago.
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Most appropriate next step: Duplex venous ultrasonography, or Doppler flow study.
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Case 12: A 21-year-old primigravida at 8 weeks gestation with sickle cell disease.
-
Husband's hemoglobin electrophoresis shows:
- Hemoglobin A: 42% (95%–98%)
- Hemoglobin A2: 3% (2%–3%)
- Hemoglobin F: 2% (0.8%–2%)
- Hemoglobin S: 53% (0%)
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Probability of fetus having sickle cell disease: ~ 50%
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Case 13: A 37-year-old primigravida at 35 weeks' gestation with hypertension, diabetes, and proteinuria.
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Serum urea nitrogen concentration of 8 mg/dL and creatinine concentration of 1 mg/dL.
- 24-hour urine collection shows 800 mg protein.
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Most likely cause of ultrasound findings: Placental dysfunction.
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Case 14:A 57-year old woman with urinary loss and history of cervical cancer.
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Physical examination showed no abnormalities.
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Genitourinary examination: Thin vaginal mucosa with a pool of fluid in the vaginal canal; postvoid residual volume less than 10 mL.
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The likely diagnosis is a Vesicovaginal fistula.
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Case 15: A 57-year-old woman with history of immediate urine loss, who had six vaginal deliveries and taking no estrogen therapy.
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Most likely diagnosis of urine: Stress Incontinence.
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Case 16: A 15-year-old girl with severe abdominal pain and a week-long history of constant pain, with irregular intervals of menses, and recent sexual activity with one partner.
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Examination shows a tender pelvic mass, a lower vagina, and a cervix not visible due to bluish bulging vaginal tissue.
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The most likely diagnosis is a Transvaginal incision and drainage of the mass.
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Case 17: A 27-year-old woman with postcoital spotting.
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A woman who has a bilateral tubal ligation at 6 months prior.
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The most likely diagnosis: Exercise-related menstrual irregularity.
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Case 18: A 32-year-old woman with increasingly irregular menses.
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Her menstrual cycle is now 45 to 60 days.
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Physical Examination shows velvety pigmented skin on the axillae and groin.
-
Increased Follicle-stimulating hormone concentration is the most likely factor.
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Case 19: A 27-year-old woman with a 3 day history of abdominal pain and a 1-day history of fever.
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Patient had an uncomplicated abortion 5 days ago.
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Findings: Tender uterus, no adnexal masses, heterogeneous endometrial mass.
-
Most likely diagnosis: Septic abortion (infection after an abortion)
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Case 20: A 19-year-old woman with lower abdominal pain and spotting that started after her last period.
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Recent history of an abortion 8 months prior.
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Most likely cause: Retained products of conception.
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Case 21: A 17-year-old primigravida with decreased fetal movement.
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Most likely cause: Placental insufficiency.
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Case 22: A 34-week pregnant woman with chronic hypertension.
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Most likely explanation for fetal heart tracing: Uteroplacental insufficiency.
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Case 23: A a 22-year-old woman with vaginal burning and discharge.
-
Patient is sexually active.
-
Vaginal discharge is gray-frothy.
-
pH of 5.
-
Microscopy shows squamous epithelial cells coated with bacteria.
-
Most appropriate pharmacotherapy: Vaginal metronidazole gel.
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Case 24: A 23-year-old pregnant woman who has not felt fetal movements for two days.
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Most likely cause of fetal demise: Uteroplacental artery thrombosis.
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Case 25: A 18-year-old woman with recent chicken pox, presenting for newborn care.
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Most appropriate care: Varicella-zoster immunoglobulin therapy for the newborn.
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Case 26: A 37-year-old woman with heavy, regular menses and a two-day history of labor-like pains and vaginal bleeding.
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Most likely cause: Incomplete abortion.
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Case 27: A 27-year-old primigravida at 7 weeks gestation who is concerned about her pregnancy.
-
Most appropriate next step in diagnosis: Measurement of serum vitamin B12 (cobalamin) concentration.
-
Case 28: A 42-year-old G2P1 at 20 weeks gestation with a history of prior Cesarean section for breach presentation and current smoking.
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Most likely explanation: Current smoking or Thrombophilia
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Case 29: A 36-year-old G2P1 at 41 weeks gestation with ruptured membranes and suspected gestational diabetes.
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Most likely explanation: Post-dates pregnancy
-
Case 30: A 42-year-old woman with urinary urgency, frequency, incontinence, and numbness below the waist.
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Most likely cause of urinary findings: Overflow incontinence secondary to bladder outlet obstruction.
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Case 31: A 32-year-old woman with a dilated cervix (5cm) despite oxytocin use.
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Most likely diagnosis: Hypotonic contractions.
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Case 32: A 32-year-old G5P4 at 40 weeks' gestation with bright red vaginal bleeding.
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The most appropriate course of action is to Obtain approval from the hospital administrator to perform an emergency cesarean delivery to adhere to the health patient's religious beliefs.
-
Case 33: A 25-year-old woman in labor at 39 weeks’ gestation, with a 6-cm dilated cervix, but the presenting part is not palpable
-
Appropriate next step: Cesarean Delivery.
-
Case 34: A 52-year-old nulligravid woman for a routine checkup.
-
Most appropriate tests: Bone densitometry.
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Case 35: A 42-year-old woman with a year-long history of vaginal bleeding.
-
Most appropriate next step in management: Hysterectomy.
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Case 36: A 30-year-old woman, gravida 3, para 2, at 10 weeks' gestation with fever, minimal vaginal bleeding, and severe pelvic pain.
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Most likely diagnosis: Septic abortion.
-
Case 37: A 32-year-old with a history of two to three seizures per year and experiencing two recent seizures and taking medication phenytoin,
-
Most appropriate next step in management: Routine prenatal care.
-
Case 38: A 27-year-old woman with pain in her arms and numbness in her hand.
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Most likely diagnosis: Thoracic outlet syndrome.
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Case 39: A 14-year-old woman with painful episodes of menstrual cramping.
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Most likely cause: Prostaglandin production.
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Case 40: A 32-year-old G1P1 at 34 weeks' gestation who is admitted to the hospital with labor and other complications.
-
Most likely obstetric complication: Pre-eclampsia.
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Case 41: A 52-year-old postmenopausal woman.
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Most appropriate diagnosis: Endometrial cancer or Breast Cancer
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Case 42: A 27-year-old primigravida, at 37 weeks’ gestation, admitted for labor with fetal heart bradycardia is diagnosed with:
-
Most likely diagnosis: Ruptured uterus
-
Case 43: A 24-year-old woman three months postpartum experiencing painful intercourse.
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Most likely management: Recommendation for use of a lubricant for the vaginal intercourse.
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Case 44: A 21-year-old woman at 41 weeks' gestation admitted to the hospital in labor with meconium-stained fluid, –Most likely step: Amnioinfusion
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Case 45: A 28-year-old nulligravid woman with severe dysmenorrhea.
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Most likely diagnosis: Endometriosis.
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Case 46: A 27-year-old woman with right lower quadrant pain and other symptoms.
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Most likely diagnosis: Ruptured corpus luteum cyst or Ectopic pregnancy.
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Case 47: A 37-year-old woman with bloody nipple discharge.
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Most likely diagnosis: Intraductal papilloma.
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Case 48: A 22-year-old primigravida at 39 weeks' gestation with ruptured membranes.
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Most likely explanation for pattern: Pre-term labor or Umbilical cord compression
-
Case 49: A 42-year-old woman seeking contraceptive advice
-
Most appropriate recommendation: Depot medroxyprogesterone.
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Case 50: A 27-year-old woman with fever and decreased breath sounds two days after a cesarean delivery
-
Most likely diagnosis: Endometritis.
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Test your knowledge with this quiz featuring various medical case studies. Each case presents unique symptoms and backgrounds, assessing your understanding of diagnoses and risk factors. Perfect for medical students or healthcare professionals looking to refresh their clinical skills.