14 Questions
What is the main active ingredient in an aspirin tablet?
Acetylsalicylic acid
What is the purpose of adding FeCl3 to an aspirin sample?
To test the purity of the aspirin
What does a purple color indicate when adding FeCl3 to an aspirin sample?
The aspirin contains impurities
What is the expected result of adding FeCl3 to a pure aspirin sample?
No color change
Why might commercial aspirin give a light salmon color with FeCl3?
It is less pure than prepared aspirin
Why is aspirin dangerous when placed on your gums?
(Homework question, answer not provided)
What is the primary use of aspirin?
To reduce pain, fever, and inflammation
What is the chemical name of aspirin?
Acetylsalicylic acid
What type of drug is aspirin?
Nonsteroidal anti-inflammatory drug (NSAID)
What is the effect of placing aspirin directly on a toothache?
It can cause more harm to the mouth
What is the recommended way to use aspirin for a toothache?
Swallowing it to enter the bloodstream
What is the recent study finding about aspirin use?
It can increase tooth regeneration
Who patented aspirin in 1899?
Bayer Company in Germany
What is the physical appearance of aspirin?
It is a white crystalline
Study Notes
Aspirin Introduction
- Aspirin is an anti-inflammatory drug used to reduce pain, fever, and/or inflammation, and as an antithrombotic.
- Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk.
- Aspirin is also known as acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID).
Aspirin Composition
- Aspirin contains active ingredient acetylsalicylic acid (a weak acid).
- Aspirin also includes inactive ingredients that help produce a consistent product.
Aspirin and Toothache
- Aspirin can help with a toothache, but only if swallowed.
- Do not place an aspirin on your toothache, as it can cause more harm.
- Swallowing aspirin may indicate it's time to visit your dentist to help look into the cause of the pain.
How Aspirin Works
- Aspirin works by blocking pain chemicals within the blood, allowing for pain relief.
- Aspirin can only work when it enters the bloodstream.
Aspirin and Tooth Regeneration
- Taking aspirin from time to time can increase tooth regeneration, making it possible to reverse tooth decay.
- Aspirin aids stem cells to develop on their own, facilitating regeneration and repair of the affected area.
History of Aspirin
- The Bayer Company in Germany patented aspirin in 1899 as a modification of salicylic acid.
Aspirin Structure and Properties
- Aspirin's chemical structure is shown in Figure 1.
- Aspirin is also known as 2-acetoxybenzoic acid acetylsalicylate, and is a white crystalline.
Aspirin Tablet Composition
- An aspirin tablet contains a small amount of aspirin (usually 300-400 mg) in a starch "binder".
- Aspirin tablets may also contain other ingredients like caffeine and buffers.
Aspirin Purity Test
- Salicylic acid contains a phenol group, which reacts with FeCl3 to form a purple complex.
- Aspirin does not contain a phenol group, so it will not react with FeCl3.
- If aspirin reacts with FeCl3 to form a purple color, it means the sample is impure and contains salicylic acid.
Procedure for Aspirin Purity Test
- Bring salicylic acid and aspirin into two test tubes.
- Add 2 ml distilled water to each test tube and shake well.
- Add 4 drops of 1% FeCl3 to each test tube and shake well.
- Observe the color change to determine the purity of the aspirin sample.
This quiz covers the properties and uses of Aspirin, an anti-inflammatory drug, and its purity test. It's a part of the Medical Chemistry course for 1st-year students at the College of Dentistry.
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