Podcast
Play an AI-generated podcast conversation about this lesson
Questions and Answers
What is the developmental process involved in repairing bone fractures?
What is the developmental process involved in repairing bone fractures?
- Osteoporosis and osteomalacia
- Chondrogenesis and osteogenic activity (correct)
- Myogenesis and adipogenic activity
- Fibrogenesis and chondrogenic activity
Which condition in children is caused by calcium deficiency and results in bone matrix abnormalities?
Which condition in children is caused by calcium deficiency and results in bone matrix abnormalities?
- Osteomalacia
- Chondrodysplasia
- Osteoporosis
- Rickets (correct)
What happens to bone cells near a fracture due to disrupted blood vessels?
What happens to bone cells near a fracture due to disrupted blood vessels?
- They undergo apoptosis (correct)
- They proliferate rapidly
- They become osteoclasts
- They differentiate into muscle cells
What is the consequence of calcium deficiency in adults that leads to reduced bone mineral density?
What is the consequence of calcium deficiency in adults that leads to reduced bone mineral density?
Signup and view all the answers
Which vitamin is important for the absorption of calcium by cells of the small intestine?
Which vitamin is important for the absorption of calcium by cells of the small intestine?
Signup and view all the answers
What is the cause of osteomalacia in adults?
What is the cause of osteomalacia in adults?
Signup and view all the answers
Flashcards are hidden until you start studying
Study Notes
Bone Fractures
- Bone fractures are repaired through a developmental process involving chondrocyte formation and osteogenic activity of major bone cells.
- Fractures disrupt blood vessels, causing bone cells near the break to die, leading to a localized hemorrhage or hematoma.
- Clotted blood is removed by macrophages, and the matrix of damaged, cell-free bone is resorbed by osteoclasts.
Rickets
- Rickets is a disease caused by calcium deficiency in children, leading to abnormal bone matrix calcification and distortion of the epiphyseal plate.
- The deficiency can be due to insufficient calcium in the diet or a failure to produce vitamin D, which is essential for Ca2+ absorption by small intestine cells.
- This results in slowed bone growth and potential deformities.
Osteomalacia
- Osteomalacia is a condition in adults characterized by deficient calcification of newly formed bone and partial decalcification of already calcified matrix.
- It is caused by calcium deficiency, which impairs bone mineralization.
Osteoporosis
- Osteoporosis is an imbalance in skeletal turnover, where bone resorption exceeds bone formation.
- This leads to calcium loss from bones and reduced bone mineral density (BMD).
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
