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Questions and Answers
What is the classification of Meclizine?
What is the classification of Meclizine?
- Antidepressant
- Analgesic
- Anticholinergic/antihistamine (correct)
- Antibiotic
What are the therapeutic actions of Meclizine?
What are the therapeutic actions of Meclizine?
Blocks cholinergic receptors in the vomiting center, has peripheral anticholinergic effects, prevention and treatment of nausea/vomiting and motion sickness.
Which substances can interact with Meclizine?
Which substances can interact with Meclizine?
- CNS depressants
- Alcohol
- Both A and B (correct)
- None of the above
How is Meclizine metabolized?
How is Meclizine metabolized?
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What are some contraindications for Meclizine use?
What are some contraindications for Meclizine use?
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What are the adverse effects of Meclizine?
What are the adverse effects of Meclizine?
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What should be assessed in nursing considerations for Meclizine?
What should be assessed in nursing considerations for Meclizine?
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Study Notes
Meclizine Overview
- Meclizine is classified as an anticholinergic and antihistamine.
- Effective in blocking cholinergic receptors within the vomiting center.
Therapeutic Uses
- Used for the prevention and treatment of nausea and vomiting (N/V) and motion sickness.
- Exhibits peripheral anticholinergic effects that assist in its therapeutic action.
Drug Interactions
- Caution is advised when combining meclizine with CNS depressants and alcohol due to potential enhanced sedative effects.
Pharmacokinetics
- Administered orally; undergoes metabolism in the liver.
- Excreted via urine and feces; can cross the placenta and enter breast milk.
Contraindications and Cautions
- Contraindicated in individuals with allergies to the drug.
- Use with caution in pregnant or lactating women, patients with narrow-angle glaucoma, benign prostatic hyperplasia, peptic ulcer disease, bronchial asthma, and hypotension.
Adverse Effects
- Common side effects include drowsiness, confusion, dry mouth, anorexia, and increased urinary frequency.
Nursing Considerations
- Assess patient allergies and medical history.
- Evaluate neurological and cardiovascular status.
- Monitor for complaints of nausea and document any emesis.
- Conduct a physical exam for baseline assessment; include skin and abdominal inspection.
- Regularly monitor relevant laboratory results for any changes.
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