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Questions and Answers
What are the brand names of Meclizine?
What are the common FDA indications for Meclizine?
What drug class does Meclizine belong to?
What is the mechanism of action (MOA) of Meclizine?
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Renal dosing adjustment is required for Meclizine.
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What dosage forms are available for Meclizine?
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What is the dosing recommendation for motion sickness for adults and children 12 years and older?
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What are some common adverse drug reactions (ADRs) associated with Meclizine?
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What are the serious adverse drug reactions (ADRs) for Meclizine?
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What monitoring parameters should be considered for Meclizine?
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Which counseling points should be noted when taking Meclizine?
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What are the drug interactions associated with Meclizine?
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What is a contraindication for Meclizine?
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Study Notes
Brand Name
- Known as Dramamine and Antivert.
Common FDA Indications
- Used to treat motion sickness and vertigo.
Drug Class
- Classified as an antihistamine and antiemetic.
Mechanism of Action (MOA)
- Functions by suppressing the vasodepressor response to histamine, with minimal inhibition of acetylcholine.
Renal Dosing Adjustment
- No renal dosing adjustment is necessary.
Available Dosage Forms
- Offered in tablet and chewable tablet formats.
Dosing Guidelines
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For Motion Sickness:
- Adults and children aged 12 years and older: 25-50 mg orally, 1 hour before departure; may repeat every 24 hours as needed.
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For Vertigo:
- Dosing ranges from 25-100 mg orally per day, divided into 1-3 doses based on clinical response.
Common Adverse Drug Reactions (ADRs)
- May cause sedation, headache, dry mouth, fatigue, and nausea.
Serious Adverse Drug Reactions (ADRs)
- No serious ADRs reported.
Monitoring Parameters
- Monitor for improvement in nausea or vertigo symptoms. Seek medical attention for severe central nervous system (CNS) toxicity signs.
Counseling Points
- Can cause drowsiness; avoid driving or operating heavy machinery until the drug's effects are known.
- Avoid alcohol and other CNS depressants during treatment.
- Taking the drug with food may reduce gastrointestinal symptoms.
- Use with caution in patients with asthma, glaucoma, or enlarged prostate due to potential anticholinergic effects.
Drug Interactions
- Care should be taken with concomitant use of CNS depressants, including opioids, benzodiazepines, and alcohol.
Contraindications
- Contraindicated in individuals with hypersensitivity to the drug.
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Description
Test your knowledge about Meclizine with these flashcards. Learn about brand names, FDA indications, drug classification, mechanisms of action, and dosing adjustments. This quiz is ideal for students and healthcare professionals looking to enhance their understanding of this medication.
