10 Questions
What is the first step in the mechanism of virus induced disease?
Attachment to the cell surface
How do viruses cause tissue damage after entering the cells?
Host cell lysis
Which phase involves the multiplication of virus and cell damage?
Eclipse phase
Which type of viruses alter the cell metabolism and lead to necrosis?
Parvo and Adeno viruses
Where does the RNA and protein synthesis take place during viral replication?
Cytoplasm
What is the primary function of viral protein (legends) in virus induced disease?
Bind with specific cellular protein on the surface of host cells
Which process immediately follows the attachment of a virus to specific cellular surface receptors?
Viral penetration by endocytosis
How do cytotoxic viruses, such as Herpes and Parvo, contribute to tissue damage?
Alter the cell metabolism and lead to necrosis
In which phase of viral replication does the multiplication of virus and cell damage occur?
Eclipse phase
What is the immediate result of viruses entering the cells during virus induced disease?
Eclipse phase (multiplication of virus and cell damage)
Study Notes
- Department of Pathology, Faculty of Veterinary Medicine, NewVally University, Egypt
- Dr. Abdel Fattah Ibrahim El Zanaty, MVSc., Ph.D. (Pathology), contact: 010 93131520
- Virus-induced disease mechanisms:
- Viruses attach to target cell surfaces using specific viral proteins and cellular proteins
- After attachment, viruses enter cells and replicate, causing damage to host cells
- Viruses inhibit host cell DNA, RNA, and protein synthesis
- Viruses damage cell membranes or promote cell fusion
- Replication of viruses inside cells results in host cell lysis
- Immune system recognizes viral proteins on cell surfaces and kills infected cells
- Viral replication process:
- Attachment to cells: Binding of viral protein to specific cellular surface receptors
- Penetration: Immediate entry into cells via endocytosis
- Eclipse phase:
- Multiplication of virus and cell damage
- RNA and protein synthesis take place in cytoplasm
- Viral release:
- Cytocidal viruses: Alter host cell metabolism and cause necrosis (Herpes, Picorna, Parvo, Adeno, Flavivirus)
- Non-cytocidal viruses: Replicated by budding.
Learn about the mechanisms of virus-induced disease, including how viruses attach to host cells and replicate inside them.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
