Mechanisms of Virus-Induced Disease
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Questions and Answers

What is the first step in the mechanism of virus induced disease?

  • Entering the cells and replication
  • Attachment to the cell surface (correct)
  • Viral release by budding
  • Replication of viruses inside cells
  • How do viruses cause tissue damage after entering the cells?

  • Recognition of viral protein by the immune system
  • Promotion of cell fusion
  • Inhibition of host cell DNA or RNA and protein synthesis
  • Host cell lysis (correct)
  • Which phase involves the multiplication of virus and cell damage?

  • Viral release by budding
  • Attachment to the cells
  • Eclipse phase (correct)
  • Penetration by endocytosis
  • Which type of viruses alter the cell metabolism and lead to necrosis?

    <p>Parvo and Adeno viruses (C)</p> Signup and view all the answers

    Where does the RNA and protein synthesis take place during viral replication?

    <p>Cytoplasm (C)</p> Signup and view all the answers

    What is the primary function of viral protein (legends) in virus induced disease?

    <p>Bind with specific cellular protein on the surface of host cells (A)</p> Signup and view all the answers

    Which process immediately follows the attachment of a virus to specific cellular surface receptors?

    <p>Viral penetration by endocytosis (A)</p> Signup and view all the answers

    How do cytotoxic viruses, such as Herpes and Parvo, contribute to tissue damage?

    <p>Alter the cell metabolism and lead to necrosis (C)</p> Signup and view all the answers

    In which phase of viral replication does the multiplication of virus and cell damage occur?

    <p>Eclipse phase (D)</p> Signup and view all the answers

    What is the immediate result of viruses entering the cells during virus induced disease?

    <p>Eclipse phase (multiplication of virus and cell damage) (D)</p> Signup and view all the answers

    Study Notes

    • Department of Pathology, Faculty of Veterinary Medicine, NewVally University, Egypt
    • Dr. Abdel Fattah Ibrahim El Zanaty, MVSc., Ph.D. (Pathology), contact: 010 93131520
    • Virus-induced disease mechanisms:
      • Viruses attach to target cell surfaces using specific viral proteins and cellular proteins
      • After attachment, viruses enter cells and replicate, causing damage to host cells
        • Viruses inhibit host cell DNA, RNA, and protein synthesis
        • Viruses damage cell membranes or promote cell fusion
        • Replication of viruses inside cells results in host cell lysis
        • Immune system recognizes viral proteins on cell surfaces and kills infected cells
    • Viral replication process:
      • Attachment to cells: Binding of viral protein to specific cellular surface receptors
      • Penetration: Immediate entry into cells via endocytosis
      • Eclipse phase:
        • Multiplication of virus and cell damage
        • RNA and protein synthesis take place in cytoplasm
      • Viral release:
        • Cytocidal viruses: Alter host cell metabolism and cause necrosis (Herpes, Picorna, Parvo, Adeno, Flavivirus)
        • Non-cytocidal viruses: Replicated by budding.

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    Description

    Learn about the mechanisms of virus-induced disease, including how viruses attach to host cells and replicate inside them.

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