Mechanisms of Virus-Induced Disease
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Questions and Answers

What is the first step in the mechanism of virus induced disease?

  • Entering the cells and replication
  • Attachment to the cell surface (correct)
  • Viral release by budding
  • Replication of viruses inside cells

How do viruses cause tissue damage after entering the cells?

  • Recognition of viral protein by the immune system
  • Promotion of cell fusion
  • Inhibition of host cell DNA or RNA and protein synthesis
  • Host cell lysis (correct)

Which phase involves the multiplication of virus and cell damage?

  • Viral release by budding
  • Attachment to the cells
  • Eclipse phase (correct)
  • Penetration by endocytosis

Which type of viruses alter the cell metabolism and lead to necrosis?

<p>Parvo and Adeno viruses (C)</p> Signup and view all the answers

Where does the RNA and protein synthesis take place during viral replication?

<p>Cytoplasm (C)</p> Signup and view all the answers

What is the primary function of viral protein (legends) in virus induced disease?

<p>Bind with specific cellular protein on the surface of host cells (A)</p> Signup and view all the answers

Which process immediately follows the attachment of a virus to specific cellular surface receptors?

<p>Viral penetration by endocytosis (A)</p> Signup and view all the answers

How do cytotoxic viruses, such as Herpes and Parvo, contribute to tissue damage?

<p>Alter the cell metabolism and lead to necrosis (C)</p> Signup and view all the answers

In which phase of viral replication does the multiplication of virus and cell damage occur?

<p>Eclipse phase (D)</p> Signup and view all the answers

What is the immediate result of viruses entering the cells during virus induced disease?

<p>Eclipse phase (multiplication of virus and cell damage) (D)</p> Signup and view all the answers

Study Notes

  • Department of Pathology, Faculty of Veterinary Medicine, NewVally University, Egypt
  • Dr. Abdel Fattah Ibrahim El Zanaty, MVSc., Ph.D. (Pathology), contact: 010 93131520
  • Virus-induced disease mechanisms:
    • Viruses attach to target cell surfaces using specific viral proteins and cellular proteins
    • After attachment, viruses enter cells and replicate, causing damage to host cells
      • Viruses inhibit host cell DNA, RNA, and protein synthesis
      • Viruses damage cell membranes or promote cell fusion
      • Replication of viruses inside cells results in host cell lysis
      • Immune system recognizes viral proteins on cell surfaces and kills infected cells
  • Viral replication process:
    • Attachment to cells: Binding of viral protein to specific cellular surface receptors
    • Penetration: Immediate entry into cells via endocytosis
    • Eclipse phase:
      • Multiplication of virus and cell damage
      • RNA and protein synthesis take place in cytoplasm
    • Viral release:
      • Cytocidal viruses: Alter host cell metabolism and cause necrosis (Herpes, Picorna, Parvo, Adeno, Flavivirus)
      • Non-cytocidal viruses: Replicated by budding.

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Learn about the mechanisms of virus-induced disease, including how viruses attach to host cells and replicate inside them.

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