Mechanisms of Particulate Deposition and Filter Efficiency

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Questions and Answers

Which mechanism primarily governs the deposition of larger air particles in the respiratory system?

  • Diffusion
  • Electrostatic Attraction
  • Interception
  • Sedimentation (correct)

What type of sampling method is most commonly used for airborne particulates?

  • Particle collection on filters (correct)
  • Optical particle measurement
  • Optical or electron microscopy
  • Particle collection on liquid medium

What is the hardest particle size to filter out according to HEPA standards?

  • 0.3 micrometers (correct)
  • 1 micrometer
  • 0.5 micrometers
  • 0.1 micrometers

Which mechanism applies primarily to irregular particles such as asbestos?

<p>Interception (C)</p> Signup and view all the answers

What is the minimum efficiency rate for HEPA filters at 0.3 microns?

<p>99.97% (B)</p> Signup and view all the answers

What primarily influences the deposition of very small aerosol particles in the lungs?

<p>Diffusion (Brownian Movement) (B)</p> Signup and view all the answers

What factor must be calibrated when sampling for airborne particulates?

<p>Flow rate of the pump (D)</p> Signup and view all the answers

Which process applies to the removal of very small particles from the air?

<p>Diffusion (D)</p> Signup and view all the answers

How is flow rate typically measured?

<p>In liters of air per minute (A)</p> Signup and view all the answers

What is the formula to determine the volume of air collected?

<p>Flow rate (lpm) multiplied by time (minutes) (D)</p> Signup and view all the answers

What unit is concentration for particulates expressed in?

<p>Milligrams per cubic meter (mg/m3) (C)</p> Signup and view all the answers

What is the maximum aerodynamic diameter for particles that the IOM sampler can collect?

<p>100 micrometers (µm) (C)</p> Signup and view all the answers

What is critical when using a cyclone for collecting respirable particles?

<p>The manufacturer’s specified flow rate (B)</p> Signup and view all the answers

Which organization provides standardized methods for air sampling to ensure compliance with permissible exposure limits?

<p>OSHA (B)</p> Signup and view all the answers

What type of particulate matter does the inhalable fraction sampling focus on?

<p>Particles with an aerodynamic diameter of up to 100 micrometers (µm) (D)</p> Signup and view all the answers

What is the primary purpose of NIOSH methods in air sampling?

<p>To provide validated techniques for sampling and analyzing contaminants (D)</p> Signup and view all the answers

What does ug/l equal in terms of concentration measurement?

<p>mg/m3 (D)</p> Signup and view all the answers

What is the role of the IOM sampler during use?

<p>To collect particles that can be inhaled and deposited in the respiratory tract (A)</p> Signup and view all the answers

Flashcards

Sedimentation

The tendency of particles to settle out of suspension due to gravity. This is more common in larger airways.

Interception

The process by which particles are removed from an airstream due to collisions with the walls of airways, especially at bifurcations or if the fibers are curved.

Inertial Impaction

The process by which particles are removed from an airstream due to changes in air direction. Larger particles are more likely to impact.

Diffusion (Brownian Movement)

The movement of very small particles, smaller than 1 micrometer, caused by random bombardments from air molecules. It significantly influences deposition in the terminal bronchioles.

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Electrostatic Attraction

The removal of airborne particles by their attraction to oppositely charged surfaces.

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Optical Particle Measurement

The measurement of airborne particulate concentrations using specialized equipment to count and size particles.

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HEPA Filter

A type of particle filter that captures a minimum of 99.97% of particles greater than 0.3 micrometers in size.

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Particle collection on filters

The most common sampling method for airborne particulates, where air passes through a filter, collecting particles for analysis.

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Flow Rate

The amount of air that flows through a sampler per unit of time, usually measured in liters per minute (lpm).

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Volume of Air Collected

The total amount of air collected during a sampling event, calculated by multiplying the flow rate by the sampling time.

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Particulate Weight

The weight of particulate matter collected on a filter, usually measured in micrograms (µg).

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Particulate Concentration

The concentration of particulate matter in the air, expressed as milligrams per cubic meter (mg/m3).

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Inhalable Fraction

The fraction of aerosol particles that can be inhaled and reach the respiratory tract, typically up to 100 micrometers (µm) in aerodynamic diameter.

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IOM Sampler

A sampling device designed to collect the inhalable fraction of airborne particulate matter. It mimics how particles enter the nose and mouth.

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Respirable Fraction

The fraction of aerosol particles that can reach the deep lung, typically particles less than 4 micrometers (µm) in aerodynamic diameter.

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Cyclone

A device designed to separate particles based on their aerodynamic size, often used to collect the respirable fraction of air.

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OSHA Sampling Methods

A standardized set of procedures developed by OSHA for sampling workplace air to determine compliance with permissible exposure limits (PELs).

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NIOSH Manual of Analytical Methods (NMAM)

A comprehensive manual developed by NIOSH providing detailed methods for sampling and analyzing workplace contaminants, emphasizing accuracy and reliability.

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Study Notes

Mechanisms of Particulate Deposition

  • Inertial impaction occurs when an airstream changes direction, causing particles to collide with surfaces.
  • Interception involves the collision of irregular-shaped particles (e.g., asbestos fibers) with surfaces, especially airway bifurcations.
  • Sedimentation occurs due to gravity, primarily in larger airways.
  • Electrostatic attraction involves charged surfaces attracting oppositely charged particles.
  • Diffusion (Brownian motion) is the random movement of very small particles bombarded by air molecules, influencing deposition in smaller airways.

Filter Efficiency

  • Filter efficiency depends on multiple deposition mechanisms.
  • Particles around 0.3 micrometers are the hardest to filter out.
  • HEPA filters remove a minimum of 99.97% of 0.3-micron contaminants.
  • Efficiency is higher for particles smaller than 0.3 micrometers.
  • Larger particles are removed through impaction and interception, while smaller ones via diffusion.

Particulate Sampling Methods

  • Total dust samples use filters to collect all particles in the air.
  • Filters are chosen based on specific sampling methods set by organizations like OSHA or NIOSH.
  • Air flow rate with calibrated pumps is crucial.
  • Concentration is expressed in mg/m³.
  • The volume of air sampled and the weight of the collected particles determine the concentration.

Size-Selective Sampling

  • Size-selective sampling focuses on specific fractions of aerosols reaching the respiratory tract.
  • Inhalable fraction (up to 100 µm aerodynamic diameter) can be collected using an IOM sampler.
  • The IOM sampler mimics human breathing patterns.
  • Respirable fraction (reaching the pulmonary spaces) can be collected using a cyclone.
  • Flow rate in cyclone sampling is critical.

OSHA and NIOSH Methods

  • OSHA and NIOSH provide standardized methods for air sampling and compliance.
  • OSHA methods focus on regulatory compliance for exposure limits.
  • NIOSH methods focus on research and validated techniques.

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