Podcast
Questions and Answers
What is the first step in the mechanism of toxicity?
What is the first step in the mechanism of toxicity?
- Repair or Dysrepair
- Cellular Dysfunction and Resultant Toxicity
- Delivery: Site of Exposure to the Target (correct)
- Reaction of the ultimate toxicant with the target molecule
Which route of exposure involves inhaling the toxicant?
Which route of exposure involves inhaling the toxicant?
- Inhale through the respiratory tract (correct)
- Can be exposed from the toxicant through the skin
- Ingest the toxicant (GI Tract)
- Absorption
What process increases the concentration of toxicants at the target site?
What process increases the concentration of toxicants at the target site?
- Reabsorption
- Pre-systemic elimination
- Distribution away from the target
- Toxication (correct)
Which step involves the transfer of chemicals from the site of exposure to systemic circulation?
Which step involves the transfer of chemicals from the site of exposure to systemic circulation?
What is the term for unprogrammed cell death?
What is the term for unprogrammed cell death?
Where does detoxification of toxicants primarily occur?
Where does detoxification of toxicants primarily occur?
What is the main difference between necrosis and apoptosis?
What is the main difference between necrosis and apoptosis?
Why is the absorption of chemicals important in determining toxicity?
Why is the absorption of chemicals important in determining toxicity?
Which route of exposure generally leads to the highest toxicity?
Which route of exposure generally leads to the highest toxicity?
What happens during necrosis in response to tissue damage?
What happens during necrosis in response to tissue damage?
How do apoptotic bodies get eliminated after cell death?
How do apoptotic bodies get eliminated after cell death?
Why is ethanol readily absorbed from the gastrointestinal tract but not through the skin?
Why is ethanol readily absorbed from the gastrointestinal tract but not through the skin?
Flashcards
What is 'Delivery' in toxicology?
What is 'Delivery' in toxicology?
Movement of a toxicant from the exposure site to the target organ or tissue.
What exposure route involves breathing in a toxicant?
What exposure route involves breathing in a toxicant?
Inhalation of a toxicant through the respiratory system.
What is Toxication?
What is Toxication?
The process by which a substance becomes more toxic.
What is Absorption?
What is Absorption?
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What is Necrosis?
What is Necrosis?
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Where does Detoxification mainly occur?
Where does Detoxification mainly occur?
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Necrosis vs. Apoptosis?
Necrosis vs. Apoptosis?
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Why is absorption crucial?
Why is absorption crucial?
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Route = Highest toxicity?
Route = Highest toxicity?
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What happens during necrosis?
What happens during necrosis?
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How are apoptotic bodies cleared?
How are apoptotic bodies cleared?
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Ethanol absorption differences?
Ethanol absorption differences?
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