Mechanism of Action of Vancomycin and Teicoplanin - Manipal University College Malaysia (2023)
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Questions and Answers

Which drug is considered the drug of choice for difficile infections?

  • Vancomycin (correct)
  • Ceftriaxone
  • Teicoplanin
  • Gentamicin

What is a common adverse effect associated with vancomycin use?

  • Red neck syndrome
  • Nephrotoxicity (correct)
  • Bronchospasm
  • Granulocytopenia

In which condition can teicoplanin be used as an alternative to vancomycin?

  • Osteomyelitis (correct)
  • Endocarditis
  • Skin infections
  • Bacterial meningitis

What symptom is associated with Red man syndrome?

<p>Chills (D)</p> Signup and view all the answers

Which drug is given along with teicoplanin for the treatment of Enterococcal endocarditis?

<p>Gentamicin (C)</p> Signup and view all the answers

What is the primary mechanism of action of vancomycin and teicoplanin?

<p>Inhibiting cell wall synthesis (A)</p> Signup and view all the answers

Which component do vancomycin and teicoplanin bind to in order to exert their mechanism of action?

<p>D-alanyl-D-alanine (C)</p> Signup and view all the answers

Why are vancomycin and teicoplanin ineffective against Gram-negative organisms?

<p>They cannot penetrate the outer cell membrane of Gram-negative bacteria (B)</p> Signup and view all the answers

In which bacterial infections is vancomycin commonly used as an alternative drug?

<p>MRSA infections (C)</p> Signup and view all the answers

Apart from intravenous administration, in which specific condition is vancomycin given orally?

<p>Pseudomembranous enterocolitis (D)</p> Signup and view all the answers

What additional cellular component do vancomycin and teicoplanin damage, contributing to their mechanism of action?

<p>Cell membrane (D)</p> Signup and view all the answers

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