Mechanism of Action of Vancomycin and Teicoplanin - Manipal University College Malaysia (2023)
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Questions and Answers

Which drug is considered the drug of choice for difficile infections?

  • Vancomycin (correct)
  • Ceftriaxone
  • Teicoplanin
  • Gentamicin
  • What is a common adverse effect associated with vancomycin use?

  • Red neck syndrome
  • Nephrotoxicity (correct)
  • Bronchospasm
  • Granulocytopenia
  • In which condition can teicoplanin be used as an alternative to vancomycin?

  • Osteomyelitis (correct)
  • Endocarditis
  • Skin infections
  • Bacterial meningitis
  • What symptom is associated with Red man syndrome?

    <p>Chills</p> Signup and view all the answers

    Which drug is given along with teicoplanin for the treatment of Enterococcal endocarditis?

    <p>Gentamicin</p> Signup and view all the answers

    What is the primary mechanism of action of vancomycin and teicoplanin?

    <p>Inhibiting cell wall synthesis</p> Signup and view all the answers

    Which component do vancomycin and teicoplanin bind to in order to exert their mechanism of action?

    <p>D-alanyl-D-alanine</p> Signup and view all the answers

    Why are vancomycin and teicoplanin ineffective against Gram-negative organisms?

    <p>They cannot penetrate the outer cell membrane of Gram-negative bacteria</p> Signup and view all the answers

    In which bacterial infections is vancomycin commonly used as an alternative drug?

    <p>MRSA infections</p> Signup and view all the answers

    Apart from intravenous administration, in which specific condition is vancomycin given orally?

    <p>Pseudomembranous enterocolitis</p> Signup and view all the answers

    What additional cellular component do vancomycin and teicoplanin damage, contributing to their mechanism of action?

    <p>Cell membrane</p> Signup and view all the answers

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