Mechanical Ventilation Cases Study

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Questions and Answers

In Case 2, what action should be taken to return the PaCO2 levels to normal?

Decrease the respiratory rate (RR) to 12 breaths/min.

What is the necessary inspiratory flow to achieve the given settings in Case 1?

The necessary inspiratory flow is 3571 L/min.

What ventilator change is appropriate for the patient in Case 3 with hyperoxemia?

The FiO2 should be decreased to 0.38.

What is the tidal volume set for the patient in Case 2 on SIMV-VC mode?

<p>The tidal volume is set at 500 ml.</p> Signup and view all the answers

What is the PEEP setting for the patient in Case 2?

<p>The PEEP setting is 5 cmH2O.</p> Signup and view all the answers

Identify the primary problem indicated by the ABG results in Case 2.

<p>The primary problem is respiratory alkalosis.</p> Signup and view all the answers

For the patient in Case 1, what is the set breathing rate?

<p>The set breathing rate is 12 breaths/min.</p> Signup and view all the answers

What would be the consequences of hyperoxemia as shown in Case 3?

<p>Hyperoxemia can lead to oxygen toxicity and various complications.</p> Signup and view all the answers

What is the primary goal when managing a patient with respiratory alkalosis as indicated in the first case?

<p>To return the PaCO2 levels to normal.</p> Signup and view all the answers

How should you adjust the mechanical ventilation settings for the patient with bilateral pneumonia experiencing mild hypoxemia?

<p>Increase PEEP by 2-3 cmH2O.</p> Signup and view all the answers

In the case of the comatose patient with a head injury, what would be the most appropriate action regarding FiO2?

<p>No change or decrease FiO2 slightly.</p> Signup and view all the answers

For the adult patient with a PIP of 41 and Pplat of 33, what should be monitored to prevent complications?

<p>Risk of hemodynamic instability and pneumothorax.</p> Signup and view all the answers

What vent settings should be modified for a patient to achieve desired PaCO2 while on AC-VC mode?

<p>Decrease the minute ventilation to adjust and achieve desired PaCO2.</p> Signup and view all the answers

When is it appropriate to use pressure control ventilation in patients with severe respiratory conditions?

<p>When the patient requires a specific pressure to avoid barotrauma.</p> Signup and view all the answers

In mechanically ventilated patients, why is monitoring blood gas values vital?

<p>To assess the effectiveness of ventilation and the patient's oxygenation status.</p> Signup and view all the answers

What does a PaO2 of 65 indicate in the context of mechanical ventilation?

<p>It indicates mild hypoxemia.</p> Signup and view all the answers

Flashcards

Inspiratory flow

The rate at which air is delivered to the lungs during inspiration.

AC-VC (Assist-Control Ventilation - Volume Control)

A ventilation mode where the ventilator delivers a preset volume of air (VT) at a set rate, regardless of the patient's effort.

SIMV-VC (Synchronized Intermittent Mandatory Ventilation - Volume Control)

A ventilation mode where the ventilator delivers a preset volume of air (VT) at a set rate, but the patient can trigger additional breaths.

Tidal Volume (VT)

The amount of air delivered to the lungs with each breath.

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PEEP (Positive End-Expiratory Pressure)

The pressure applied to the lungs at the end of expiration. It prevents lung collapse.

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Respiratory Acidosis

A state where the body is not getting enough oxygen or is eliminating too much carbon dioxide, leading to a low pH in the blood.

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Respiratory Alkalosis

A state where the body is getting too much oxygen or eliminating too much carbon dioxide, leading to a high pH in the blood.

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FiO2 (Fraction of Inspired Oxygen)

The fraction of oxygen in the air delivered to the lungs.

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What is respiratory alkalosis?

Respiratory alkalosis occurs when the body eliminates too much carbon dioxide (CO2). Elevated pH and low PaCO2 are characteristic of this condition.

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What is the initial treatment for respiratory alkalosis?

The goal is to adjust the ventilation settings, specifically the tidal volume (Vt), to achieve a desired PaCO2 level. This is the first step in addressing respiratory alkalosis.

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How do we manipulate PIP in a ventilator?

When the vent mode is Pressure Control (PC) or Pressure Regulated Volume Control (PRVC), manipulating the peak inspiratory pressure (PIP) allows for adjustments to achieve the desired tidal volume. This approach is particularly suitable for patients with respiratory alkalosis.

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What is mild hypoxemia?

Mild hypoxemia refers to a mild reduction in blood oxygen levels (PaO2). This often indicates the need to increase oxygen delivery to improve the patient's blood oxygenation.

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How do we address mild hypoxemia?

Increasing the Positive End-Expiratory Pressure (PEEP) helps to improve oxygen exchange in the lungs, thereby addressing mild hypoxemia.

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Why is PEEP important?

PEEP (Positive End-Expiratory Pressure) is a ventilation parameter that helps to keep the alveoli open at the end of expiration. It is vital for maintaining lung volume and improving oxygen exchange.

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What does a high PIP indicate?

When a patient's PIP (Peak Inspiratory Pressure) significantly exceeds their plateau pressure (Pplat), it suggests a high airway resistance. This can lead to complications like ventilator-induced lung injury (VILI). By manipulating PIP, we can potentially minimize VILI.

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What are the risks associated with high PEEP?

A high PEEP level (above 12 cmH2O) can increase the risk of complications, such as hemodynamic instability and pneumothorax. These complications are related to the pressure exerted on the lungs and surrounding structures.

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Study Notes

Case 1 Ventilatory Settings

  • Patient ventilated with AC-VC, VT 1000 ml, Set Rate = 12 breaths/min, I:E Ratio = 1:2 in constant flow waveform
  • Inspiratory flow necessary to achieve settings is 35.71 L/min

Case 2 Patient with Bilateral Pneumonia

  • 65-kg IBW man with bilateral pneumonia
  • Ventilated on SIMV-VC mode
  • VT=500 ml, SIMV rate= 16
  • No spontaneous breaths.
  • FiO2=0.40, PEEP = 5
  • ABG results: pH 7.49, PaCO2 30, PaO2 85
  • Action: Decrease RR to 12 breaths/min to achieve desired PaCO2

Case 3 Hyperoxemia

  • Patient mechanically ventilated with AC-VC, VT 600, set Rate 12, FiO2 0.65, PEEP 10.
  • ABG: pH 7.41, PaCO2 38, PaO2 156
  • Action: Decrease FiO2 to 0.38 to achieve desired PaO2

Case 4 Respiratory Alkalosis

  • 55-kg IBW adult patient ventilated on SIMV-PC mode
  • Set P = 30 cmH2O, exhaled V₁= 660 ml, Rate=12, no spontaneous efforts.
  • ABG results: pH=7.55, PaCO2=28, PaO2=87 on FiO2 of 0.45
  • Action: Decrease VT to 462 to achieve desired PaCO2

Case 5 Mild Hypoxemia

  • Adult patient with bilateral pneumonia ventilated on AC-VC mode
  • V₁= 500 ml, Rate=14, FiO2 0.60, PEEP 6 cmH2O
  • ABG results: pH=7.41, PaCO2=44, HCO3=25, PaO2=65
  • Action: Increase PEEP 2-3 cmH2O

Case 6 Closed Head Injury

  • Comatose and apneic patient with closed head injury mechanically ventilated on AC-VC mode
  • VT= 600 ml (8 ml/kg), set Rate=10, no spontaneous efforts.
  • ABG results: pH=7.39, PaCO2=40, PaO2=108 on FiO2 of 0.30
  • Action: No change or decrease FiO2 slightly

Case 7 Respiratory Acidosis and Hypoxemia

  • Adult patient (60 kg IBW) ventilated on AC-VC mode
  • VT=500 ml, set rate=17, PEEP=12
  • Measured PIP= 41, Pplat = 33
  • ABG results: pH=7.31, PaCO2=51, PaO2 54, HCO3=22, FiO2=0.60
  • Action: Change to AC-PC mode, set appropriate PIP until VT 500ml thereby Pplat. 230, increase RR to 21, increase PEEP 2-3 cmH2O

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