20 Questions
What is the main objective of understanding material properties in the tabletting process?
To improve tabletting process by manipulating material properties and to have better flexibility during formulation.
How do excipients added to the formulation affect tablet properties?
They influence tablet properties such as hardness and dissolution.
What is the significance of studying particle size distribution in tablet manufacturing?
It helps to understand the influence of material properties on tabletting process.
What is the importance of having a plastic property in material formulation during compression?
To allow permanent deformation during compression
What is the relationship between compaction pressure and tablet strength?
Increased compaction pressure can lead to increased tablet strength.
What is the purpose of surface area analysis in tablet manufacturing?
To understand the influence of material properties on tabletting process.
How can crystal engineering be used to improve material properties?
By modifying the crystalline structure physically or chemically to produce particles with desired properties
What is the effect of changing crystalline properties on tablet compaction?
It can influence the mechanical behavior of the material
How can surface modification of particles influence dissolution?
By changing the surface area of the particles, which can affect dissolution rates
What is the significance of particle size distribution in powder properties?
It affects the flow and mixing properties of the powder
What is the type of deformation that occurs when the molecular bonds of a material change location, resulting in a permanent change in shape?
Irreversible plastic deformation
Why is particle size an important factor to consider during the tableting process?
Because particles of different sizes can have an influence on the final product, affecting its strength and properties.
What is the consequence of elastic deformation during the tableting process?
The tablet may bounce back or lose its shape when the pressure is released, leading to problems such as capping and lamination.
How can particle shape influence the tableting process?
Particle shape can affect the bonding and compaction of particles, resulting in tablets with varying strengths and properties.
What is the significance of surface area analysis in the context of tableting?
It can provide insight into the material properties and behavior of the powder blend during compaction.
What happens to the powder particles when they are compressed in a tablating machine?
The particles are forced to come closer together, leading to rearrangement and clearing of gaps and void spaces.
What is the result of applying increasing pressure to a mass of powder in a dye?
The particles are packed together, leading to the clearing of void spaces and eventual cessation of movement.
What is the significance of particle size distribution in understanding tablet properties?
Particle size distribution is important as it affects the surface area and porosity of the powder, influencing the final tablet properties.
How does compaction pressure affect tablet strength?
Compaction pressure influences tablet strength by increasing the bonding between particles, leading to a stronger tablet.
What is the purpose of surface area analysis in understanding material properties?
Surface area analysis helps to understand the interaction between particles and their surroundings, influencing tablet properties.
Learn about the mechanical properties of materials, including elasticity, plasticity, and surface properties. Understand the importance of these properties in various applications.
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