Mechanical Properties of Materials
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Questions and Answers

What is the main objective of understanding material properties in the tabletting process?

To improve tabletting process by manipulating material properties and to have better flexibility during formulation.

How do excipients added to the formulation affect tablet properties?

They influence tablet properties such as hardness and dissolution.

What is the significance of studying particle size distribution in tablet manufacturing?

It helps to understand the influence of material properties on tabletting process.

What is the importance of having a plastic property in material formulation during compression?

<p>To allow permanent deformation during compression</p> Signup and view all the answers

What is the relationship between compaction pressure and tablet strength?

<p>Increased compaction pressure can lead to increased tablet strength.</p> Signup and view all the answers

What is the purpose of surface area analysis in tablet manufacturing?

<p>To understand the influence of material properties on tabletting process.</p> Signup and view all the answers

How can crystal engineering be used to improve material properties?

<p>By modifying the crystalline structure physically or chemically to produce particles with desired properties</p> Signup and view all the answers

What is the effect of changing crystalline properties on tablet compaction?

<p>It can influence the mechanical behavior of the material</p> Signup and view all the answers

How can surface modification of particles influence dissolution?

<p>By changing the surface area of the particles, which can affect dissolution rates</p> Signup and view all the answers

What is the significance of particle size distribution in powder properties?

<p>It affects the flow and mixing properties of the powder</p> Signup and view all the answers

What is the type of deformation that occurs when the molecular bonds of a material change location, resulting in a permanent change in shape?

<p>Irreversible plastic deformation</p> Signup and view all the answers

Why is particle size an important factor to consider during the tableting process?

<p>Because particles of different sizes can have an influence on the final product, affecting its strength and properties.</p> Signup and view all the answers

What is the consequence of elastic deformation during the tableting process?

<p>The tablet may bounce back or lose its shape when the pressure is released, leading to problems such as capping and lamination.</p> Signup and view all the answers

How can particle shape influence the tableting process?

<p>Particle shape can affect the bonding and compaction of particles, resulting in tablets with varying strengths and properties.</p> Signup and view all the answers

What is the significance of surface area analysis in the context of tableting?

<p>It can provide insight into the material properties and behavior of the powder blend during compaction.</p> Signup and view all the answers

What happens to the powder particles when they are compressed in a tablating machine?

<p>The particles are forced to come closer together, leading to rearrangement and clearing of gaps and void spaces.</p> Signup and view all the answers

What is the result of applying increasing pressure to a mass of powder in a dye?

<p>The particles are packed together, leading to the clearing of void spaces and eventual cessation of movement.</p> Signup and view all the answers

What is the significance of particle size distribution in understanding tablet properties?

<p>Particle size distribution is important as it affects the surface area and porosity of the powder, influencing the final tablet properties.</p> Signup and view all the answers

How does compaction pressure affect tablet strength?

<p>Compaction pressure influences tablet strength by increasing the bonding between particles, leading to a stronger tablet.</p> Signup and view all the answers

What is the purpose of surface area analysis in understanding material properties?

<p>Surface area analysis helps to understand the interaction between particles and their surroundings, influencing tablet properties.</p> Signup and view all the answers

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