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Questions and Answers
What does IC50 represent in toxicity measurements?
What does IC50 represent in toxicity measurements?
Which term refers to the organs that can be damaged by xenobiotics?
Which term refers to the organs that can be damaged by xenobiotics?
What is the purpose of using EC50 in toxicity assessments?
What is the purpose of using EC50 in toxicity assessments?
What characterizes a toxic effect in organisms?
What characterizes a toxic effect in organisms?
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Which of the following statements is true about IC50 and EC50?
Which of the following statements is true about IC50 and EC50?
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Study Notes
Measurement of Effects
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EC50:
- Represents the concentration at which a substance causes 50% of the maximum effect in an organism.
- Typically used for effects other than lethality.
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IC50:
- Stands for Inhibitory Concentration.
- Represents the concentration that leads to a 50% reduction in the normal response of a test organism.
- Commonly applied to measure the growth inhibition in seedlings, algae, and other biological organisms.
Types of Toxicity
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Toxic Effect:
- Refers to the adverse physiological response of an organism due to exposure to toxic substances (xenobiotics) or their metabolites.
- Specific organs affected by toxins are termed target organs, with the potential for multiple target organs for each toxic substance.
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Description
This quiz covers key concepts related to the measurement of toxic effects, focusing on EC50 and IC50 values. Additionally, it explores types of toxicity and the physiological responses caused by toxic substances. Dive into the understanding of how these measurements are applied in biological contexts.