Measurement and Types of Toxicity
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Questions and Answers

What does IC50 represent in toxicity measurements?

  • The threshold level of exposure for chronic effects
  • The maximum concentration considered safe for organisms
  • The concentration at which 50% of organisms die
  • Inhibitory concentration that decreases normal response by 50% (correct)
  • Which term refers to the organs that can be damaged by xenobiotics?

  • Non-target organs
  • Target organs (correct)
  • Secondary organs
  • Vital organs
  • What is the purpose of using EC50 in toxicity assessments?

  • To determine lethal concentrations
  • To measure growth rates of plants
  • To report non-fatal effects (correct)
  • To identify all target organs of a toxin
  • What characterizes a toxic effect in organisms?

    <p>It damages specific organs from exposure to toxins</p> Signup and view all the answers

    Which of the following statements is true about IC50 and EC50?

    <p>IC50 measures a decrease in normal response while EC50 reports other effects</p> Signup and view all the answers

    Study Notes

    Measurement of Effects

    • EC50:

      • Represents the concentration at which a substance causes 50% of the maximum effect in an organism.
      • Typically used for effects other than lethality.
    • IC50:

      • Stands for Inhibitory Concentration.
      • Represents the concentration that leads to a 50% reduction in the normal response of a test organism.
      • Commonly applied to measure the growth inhibition in seedlings, algae, and other biological organisms.

    Types of Toxicity

    • Toxic Effect:
      • Refers to the adverse physiological response of an organism due to exposure to toxic substances (xenobiotics) or their metabolites.
      • Specific organs affected by toxins are termed target organs, with the potential for multiple target organs for each toxic substance.

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    Description

    This quiz covers key concepts related to the measurement of toxic effects, focusing on EC50 and IC50 values. Additionally, it explores types of toxicity and the physiological responses caused by toxic substances. Dive into the understanding of how these measurements are applied in biological contexts.

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