Measles
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Questions and Answers

What is the name of the characteristic skin rash that occurs in measles?

  • Maculopapular
  • Morbilliform (correct)
  • Petechial
  • Urticarial
  • Which of the following is not a common complication of measles in healthy individuals?

  • Otitis media
  • Bronchopneumonia
  • Encephalitis
  • Meningitis (correct)
  • What is the recommended method of transporting measles virus samples to the laboratory?

  • On ice (correct)
  • At room temperature
  • Frozen at -20°C
  • Frozen at -70°C
  • What is the name of the white spots that may appear on the buccal mucosa of measles patients?

    <p>Koplik spots</p> Signup and view all the answers

    What type of antibody is used to confirm a recent measles infection by enzyme immunoassay (EIA)?

    <p>IgM</p> Signup and view all the answers

    What are the characteristic prodrome symptoms of measles?

    <p>Cough, coryza, and conjunctivitis</p> Signup and view all the answers

    Which individuals are more likely to experience severe measles?

    <p>Young, malnourished, and immunocompromised individuals</p> Signup and view all the answers

    How can healthcare facilities minimize the potential for healthcare-associated transmission of measles?

    <p>All of the above</p> Signup and view all the answers

    How long does it take for IgM to be produced in response to measles infection after the onset of the rash?

    <p>72 hours</p> Signup and view all the answers

    How should measles virus samples be transported and stored?

    <p>A and C</p> Signup and view all the answers

    There is a suspected case of measles in the ED of a facility, and the patient has been admitted. A nasopharyngeal swab was taken, placed in viral transport media, and sent to the lab where it was frozen at -20°C for 12 hours and then thawed and placed in culture. The culture results are negative for measles virus. Why IP request to place the patient in an airborne infection isolation room?

    <p>All of the above</p> Signup and view all the answers

    How can a specific diagnosis of measles be made?

    <p>All of the above</p> Signup and view all the answers

    What is the name of the virus that causes measles?

    <p>Rubeola</p> Signup and view all the answers

    What is the most contagious phase of measles infection?

    <p>Catarrhal prodromal phase</p> Signup and view all the answers

    What are the whitish spots on the buccal mucosa that are distinctive for measles called?

    <p>Koplik spots</p> Signup and view all the answers

    What is the best method to confirm a recent measles infection?

    <p>Serologic testing</p> Signup and view all the answers

    What is the recommended vaccination schedule for measles prevention in adults at high risk?

    <p>Two doses of MMR vaccine</p> Signup and view all the answers

    Measles is primarily transmitted through:

    <p>Airborne spread</p> Signup and view all the answers

    How long is the incubation period for measles?

    <p>12 to 14 days</p> Signup and view all the answers

    Which of the following is a key diagnostic sign and pathognomonic (distinctive) for measles?

    <p>Cough and Koplik spots</p> Signup and view all the answers

    What is the characteristic pattern of the measles rash?

    <p>Downward, from the face to the lower extremities</p> Signup and view all the answers

    What are Koplik spots?

    <p>whitish, spots on the buccal mucosa</p> Signup and view all the answers

    How can a recent measles infection be diagnosed?

    <p>Both a and b</p> Signup and view all the answers

    There is a specific antiviral therapy available for the treatment of measles.

    <p>False</p> Signup and view all the answers

    Measles patients most contagious

    <p>All of the above</p> Signup and view all the answers

    Because of the potential for rapid spread, one confirmed case of this disease is considered an urgent public health situation, and the IP should immediately report suspected and confirmed cases to the health department:

    <p>Measles</p> Signup and view all the answers

    A measles exposure from a patient in a clinic was identified and an exposure workup was initiated. A staff exposure was defined as "nonimmune HCP with more than 5 minutes of same-room contact or face-to-face contact with the index patient." Forty eight HCP were identified as possible exposures. Of these, 44 had documented immunity to measles. Of the remaining HCP, three did not have the same room or face-to-face contact. How many HCP were at risk of developing measles because of this exposure?

    <p>1</p> Signup and view all the answers

    An adult patient is admitted through the Emergency Department with a 1-day history of rash, fever, and cough. The attending physician is concerned that the patient has measles, as the patient cannot recall whether he has had measles disease or vaccine in the past. The serum sample does not contain measles- specific IgG or IgM antibodies. What is the significance of this finding?

    <p>The patient might be infected with measles</p> Signup and view all the answers

    There is a suspected case of measles in the ED of a facility, and the patient has been admitted. A nasopharyngeal swab was taken, placed in viral transport media, and sent to the lab where it was frozen at -20°C for 12 hours and then thawed and placed in culture. The culture results are negative for measles virus. Which of the following should the IP request for this patient? ...................

    1. A new sample should be collected and placed in a -20°C environment immediately
    2. A new sample should be collected and placed in culture immediately
    3. The patient should be placed in an airborne infection isolation room
    4. The patient should be placed in a standard room without isolation precautions

    <p>1</p> Signup and view all the answers

    Which of the following is not confirmatory of an active measles infection?

    <p>Rash in a patient nonimmune to measles</p> Signup and view all the answers

    The rash in measels appears after how many days from catarrhal prodromal phase

    <p>2 to 4 days</p> Signup and view all the answers

    • What is one of the acceptable presumptive evidence of immunity against measles?

    <p>Written documentation of adequate vaccination</p> Signup and view all the answers

    How many doses of a measles-containing vaccine are required for school-age children and adults who are at high risk of measles exposure?

    <p>Two</p> Signup and view all the answers

    Which of the following groups of adults are considered at high risk of measles exposure and need two doses of measles-containing vaccine?

    <p>College students, healthcare personnel, and international travelers</p> Signup and view all the answers

    What is the minimum age for receiving the first dose of a measles-containing vaccine for preschool-age children and adults who are not at high risk of measles exposure?

    <p>One year</p> Signup and view all the answers

    What type of antibody indicates a past or recent infection with measles or vaccination against measles?

    <p>Measles IgG</p> Signup and view all the answers

    Anyone who works in health care, even if he was born before 1957, must prove that he received Measles and Mumps vaccinations unless they have a history of physician-diagnosed or laboratory-confirmed immunity (IgG)

    <p>True</p> Signup and view all the answers

    Study Notes

    Measles Characteristics

    • The characteristic skin rash that occurs in measles is known as a maculopapular rash.
    • Koplik spots are white spots that may appear on the buccal mucosa of measles patients.

    Measles Complications

    • Common complications of measles in healthy individuals do not include otitis media, diarrhea, and pneumonia.
    • Severe measles is more likely to occur in individuals who are immunocompromised, pregnant, or have Vitamin A deficiency.

    Measles Diagnosis

    • A specific diagnosis of measles can be made by detecting measles IgM antibodies in serum or saliva.
    • The best method to confirm a recent measles infection is by enzyme immunoassay (EIA).
    • Detection of measles RNA in respiratory secretions or urine also confirms measles infection.

    Measles Transmission

    • Measles is primarily transmitted through direct contact with infectious droplets from the nose, mouth, or throat of an infected person.
    • The incubation period for measles is 10-14 days.
    • The most contagious phase of measles infection is 2-4 days before the onset of symptoms.

    Measles Prevention

    • The recommended vaccination schedule for measles prevention in adults at high risk is two doses of measles-containing vaccine.
    • Adults at high risk of measles exposure include healthcare workers, students in post-secondary educational institutions, and individuals who travel internationally.
    • The minimum age for receiving the first dose of a measles-containing vaccine for preschool-age children and adults who are not at high risk of measles exposure is 12 months.

    Measles Management

    • There is no specific antiviral therapy available for the treatment of measles.
    • One confirmed case of measles is considered an urgent public health situation, and the infection preventionist (IP) should immediately report suspected and confirmed cases to the health department.
    • Healthcare facilities can minimize the potential for healthcare-associated transmission of measles by implementing airborne infection isolation precautions.

    Measles Laboratory Testing

    • Measles virus samples should be transported and stored at -70°C or below.
    • IgM antibodies are produced in response to measles infection within 1-3 days after the onset of the rash.

    Measles Infection Control

    • Individuals who are not immune to measles should be placed in an airborne infection isolation room.
    • To minimize the potential for healthcare-associated transmission of measles, healthcare facilities should implement airborne infection isolation precautions.

    Measles Immunity

    • One of the acceptable presumptive evidence of immunity against measles is a documented history of measles vaccination or physician-diagnosed measles disease.
    • Anyone who works in healthcare must prove that they received measles vaccinations or have a history of physician-diagnosed or laboratory-confirmed immunity (IgG) unless they were born before 1957.

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