MCAT Organic Chemistry: Functional Groups
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Questions and Answers

What is the term for a compound with a hydroxyl group (-OH)?

  • Aldehyde
  • Alcohol (correct)
  • Ester
  • Ketone
  • What is the term for a carbonyl group (C=O) at the end of a carbon chain?

  • Alcohol
  • Ketone
  • Carboxylic acid
  • Aldehyde (correct)
  • What type of functional group is represented by R-CO-R' where R and R' are alkyl groups?

  • Ester
  • Ketone (correct)
  • Alcohol
  • Amide
  • What is the priority order of functional groups?

    <p>Carboxylic acid, Anhydride, Ester</p> Signup and view all the answers

    Which of the following is classified as a hydrocarbon with a single carbon atom?

    <p>Methyl</p> Signup and view all the answers

    What is the definition of a Carboxylic acid?

    <p>A functional group characterized by a carbonyl and a hydroxyl group (-COOH).</p> Signup and view all the answers

    What characterizes an Amide?

    <p>A functional group that contains a carbonyl group directly attached to a nitrogen atom.</p> Signup and view all the answers

    What is the significance of a Disulfide bond?

    <p>A covalent bond formed between the sulfur atoms of two cysteine residues.</p> Signup and view all the answers

    What does the term Ether refer to?

    <p>A functional group where an oxygen atom is connected to two alkyl or aryl groups.</p> Signup and view all the answers

    What characterizes a Thioester?

    <p>A functional group that contains a carbonyl adjacent to a sulfur atom.</p> Signup and view all the answers

    Study Notes

    Functional Groups in Organic Chemistry

    • Alcohol: Organic compounds characterized by the presence of a hydroxyl (-OH) group.

    • Aldehyde: Contains a carbonyl group (C=O) with a hydrogen atom attached, typically at the end of a carbon chain.

    • Ketone: Features a carbonyl group (C=O) bonded to two carbon atoms, typically found within a carbon chain.

    • Carboxylic Acid: Contains a carboxyl group (-COOH), exhibiting acidic properties due to the presence of the hydroxyl and carbonyl groups.

    • Ester: Formed from a reaction between a carboxylic acid and an alcohol, characterized by the -COO- group.

    • Amide: Derived from carboxylic acids where the -OH group is replaced by an amine or ammonia, featuring the -CONH2 group.

    • Anhydride: Formed by the dehydration of two carboxylic acids, contains two acyl groups bound to the same oxygen atom.

    Priority of Functional Groups

    • Functional groups ranked in decreasing order of priority for naming:
      • Carboxylic acid
      • Anhydride
      • Ester
      • Amide
      • Aldehyde
      • Ketone
      • Alcohol
      • Alkene
      • Alkyne
      • Alkane

    Common Alkyl and Acyclic Groups

    • Methyl: A one-carbon (CH3) substituent derived from methane.

    • Ethyl: A two-carbon (C2H5) substituent derived from ethane.

    • Phenyl: A cyclic group derived from benzene, represented as C6H5; often reacts as an aromatic substituent.

    • Acetyl: An important functional group derived from acetic acid, characterized by the -COCH3 structure.

    Additional Functional Groups

    • Enol: Contains a carbon-carbon double bond adjacent to a hydroxyl group; less stable than its keto form.

    • Ether: Comprised of two alkyl or aryl groups connected through an oxygen atom (-R-O-R').

    • Amino: Contains an amine group (-NH2), often a basic part of amino acids.

    • Amido: Related to amides, where the functional group also includes an amine.

    • Imine: Features a carbon-nitrogen double bond (C=N), formed by the condensation of an amine and a carbonyl compound.

    • Schiff Base: A specific type of imine formed from the reaction of an amine and a carbonyl compound.

    • Sulfhydryl: Contains a thiol group (-SH), important in the structure of some proteins and enzymes.

    • Disulfide: Comprising two sulfhydryl groups that form a -S-S- bond, often found in protein structures.

    • Thioester: Similar to esters, but with a sulfur atom in place of the oxygen; important in biochemical reactions.

    • Phosphoryl: Involves a phosphorus atom bonded to oxygen atoms, key in energy transfer processes.

    • Phosphoanhydride: Characterized by the bond between two phosphate groups, significant in ATP and energy metabolism.

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    Test your knowledge of key functional groups in organic chemistry with these flashcards. Familiarize yourself with their definitions and classifications to prepare efficiently for the MCAT exam.

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