3 Questions
What is the main evidence that lowering IOP reduces the risk of progression of POAG?
Advanced Glaucoma Intervention Study – AGIS
What is the current status of controlled trials for POAG?
They do not exist
What is necessary to help stop the progression of POAG in some patients?
Lowering of IOP
Study Notes
- There is evidence that lowering IOP reduces the risk of progression of POAG (Advanced Glaucoma Intervention Study – AGIS, Early Manifest Glaucoma Trial – EMGT).
- To date, there is no controlled trials for POAG, with randomization to treatment or observation.
- A multicenter clinical trial based in the UK is under-way which will hopefully address this.
- For some POAG patients, lowering of IOP does not stop their progression.
- Searching for other reversible risk factors for POAG is essential.
Test your knowledge about primary open-angle glaucoma (POAG) and its treatment approaches. Explore the challenges in managing POAG and the ongoing research in this field.
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