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Questions and Answers
What is the main evidence that lowering IOP reduces the risk of progression of POAG?
What is the main evidence that lowering IOP reduces the risk of progression of POAG?
- Early Manifest Glaucoma Trial – EMGT
- Advanced Glaucoma Intervention Study – AGIS (correct)
- A multicenter clinical trial based in the UK
- Searching for other reversible risk factors for POAG
What is the current status of controlled trials for POAG?
What is the current status of controlled trials for POAG?
- They exist and randomization to treatment or observation has been done
- They exist but randomization to treatment or observation has not been done
- They do not exist (correct)
- They exist but only randomization to treatment has been done
What is necessary to help stop the progression of POAG in some patients?
What is necessary to help stop the progression of POAG in some patients?
- Lowering of IOP (correct)
- A multicenter clinical trial based in the UK
- Searching for other reversible risk factors for POAG
- Randomization to treatment or observation
Study Notes
- There is evidence that lowering IOP reduces the risk of progression of POAG (Advanced Glaucoma Intervention Study – AGIS, Early Manifest Glaucoma Trial – EMGT).
- To date, there is no controlled trials for POAG, with randomization to treatment or observation.
- A multicenter clinical trial based in the UK is under-way which will hopefully address this.
- For some POAG patients, lowering of IOP does not stop their progression.
- Searching for other reversible risk factors for POAG is essential.
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Test your knowledge about primary open-angle glaucoma (POAG) and its treatment approaches. Explore the challenges in managing POAG and the ongoing research in this field.
