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Primary Open-Angle Glaucoma Quiz

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Questions and Answers

What is the main evidence that lowering IOP reduces the risk of progression of POAG?

Early Manifest Glaucoma Trial – EMGT

Advanced Glaucoma Intervention Study – AGIS (correct)

A multicenter clinical trial based in the UK

Searching for other reversible risk factors for POAG

What is the current status of controlled trials for POAG?

They exist and randomization to treatment or observation has been done

They exist but randomization to treatment or observation has not been done

They do not exist (correct)

They exist but only randomization to treatment has been done

What is necessary to help stop the progression of POAG in some patients?

Lowering of IOP (correct)

A multicenter clinical trial based in the UK

Searching for other reversible risk factors for POAG

Randomization to treatment or observation

Study Notes

There is evidence that lowering IOP reduces the risk of progression of POAG (Advanced Glaucoma Intervention Study – AGIS, Early Manifest Glaucoma Trial – EMGT).
To date, there is no controlled trials for POAG, with randomization to treatment or observation.
A multicenter clinical trial based in the UK is under-way which will hopefully address this.
For some POAG patients, lowering of IOP does not stop their progression.
Searching for other reversible risk factors for POAG is essential.

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Description

Test your knowledge about primary open-angle glaucoma (POAG) and its treatment approaches. Explore the challenges in managing POAG and the ongoing research in this field.