Mastocytosis Overview
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Questions and Answers

Mastocytosis is caused by the clonal proliferation of erythrocytes.

False

Only a quarter of patients with mastocytosis report experiencing bone pains.

True

Symptoms of mastocytosis can include flushing and sweating due to histamine release.

True

Hepatosplenomegaly is a symptom commonly associated with mastocytosis.

<p>True</p> Signup and view all the answers

Mastocytosis primarily affects the skin with no impact on the skeleton.

<p>False</p> Signup and view all the answers

Study Notes

Mastocytosis Overview

  • Mastocytosis is a disease caused by the clonal proliferation of mast cells.
  • Symptoms often include histamine-related effects like flushing, sweating, diarrhea, and abdominal pain.
  • Bone pain is reported by about a quarter of patients.
  • Skeletal involvement can be focal (typically in the spine) or widespread, with increased bone density.
  • Other potential features are hepatosplenomegaly and lymph node enlargement (retroperitoneal, mesenteric, periportal).

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Description

This quiz covers the essential information about mastocytosis, a disease marked by the proliferation of mast cells. Key symptoms such as flushing, pain, and skeletal involvement will be discussed, alongside other manifestations like hepatosplenomegaly. Test your knowledge on this complex condition!

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