Mastering the Role of Oxaloacetate (OAA) in Metabolic Pathways Quiz
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Questions and Answers

Which process depletes oxaloacetate (OAA) and prevents acetyl CoA entry into Krebs Cycle?

  • Glycolysis
  • Gluconeogenesis (correct)
  • Beta-oxidation
  • Fatty acid synthesis

What happens if oxaloacetate (OAA) is depleted in the TCA cycle?

  • PDH complex is activated
  • Pyruvate Carboxylase is activated
  • TCA cycle stops (correct)
  • Gluconeogenesis stops

What activates Pyruvate Carboxylase allosterically?

  • ATP
  • Oxaloacetate
  • Pyruvate
  • Acetyl CoA (correct)

What determines the entry of Acetyl CoA into Krebs cycle?

<p>OAA availability (B)</p> Signup and view all the answers

What happens when acetyl CoA accumulates in the cell?

<p>Pyruvate Carboxylase is activated (C)</p> Signup and view all the answers

What happens when acetyl CoA levels are low in the cell?

<p>Pyruvate is primarily oxidized by PDH complex (C)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing oxaloacetate (OAA) in the cell?

<p>Pyruvate Carboxylase (C)</p> Signup and view all the answers

What is the effect of OAA depletion on the TCA cycle?

<p>TCA cycle stops (D)</p> Signup and view all the answers

What is the effect of acetyl CoA accumulation on Pyruvate Carboxylase activity?

<p>Activates Pyruvate Carboxylase (C)</p> Signup and view all the answers

Which process depletes oxaloacetate (OAA) and prevents acetyl CoA entry into Krebs Cycle?

<p>Gluconeogenesis (A)</p> Signup and view all the answers

What happens if oxaloacetate (OAA) is depleted in the TCA cycle?

<p>TCA cycle stops (B)</p> Signup and view all the answers

What activates Pyruvate Carboxylase allosterically?

<p>Acetyl CoA (D)</p> Signup and view all the answers

What determines the entry of Acetyl CoA into Krebs cycle?

<p>OAA availability (B)</p> Signup and view all the answers

What happens when acetyl CoA accumulates in the cell?

<p>Pyruvate Carboxylase is activated (B)</p> Signup and view all the answers

What happens when acetyl CoA levels are low in the cell?

<p>Pyruvate is primarily oxidized by PDH complex (B)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing oxaloacetate (OAA) in the cell?

<p>Pyruvate Carboxylase (A)</p> Signup and view all the answers

What is the role of OAA in the TCA cycle?

<p>Provides OAA to the TCA cycle (B)</p> Signup and view all the answers

What is the effect of OAA depletion on the TCA cycle?

<p>TCA cycle stops (B)</p> Signup and view all the answers

What is the effect of acetyl CoA accumulation on Pyruvate Carboxylase activity?

<p>Activates Pyruvate Carboxylase (D)</p> Signup and view all the answers

What is the primary purpose of oxaloacetate (OAA) synthesis?

<p>To synthesize glucose (C)</p> Signup and view all the answers

What happens if OAA is depleted in the body?

<p>TCA cycle will stop (D)</p> Signup and view all the answers

What is the role of Pyruvate Carboxylase in the body?

<p>To synthesize glucose (B)</p> Signup and view all the answers

What activates Pyruvate Carboxylase?

<p>Acetyl CoA (A)</p> Signup and view all the answers

What determines the entry of Acetyl CoA into the Krebs cycle?

<p>The availability of OAA (D)</p> Signup and view all the answers

What depletes OAA in the body?

<p>Gluconeogenesis (B)</p> Signup and view all the answers

What happens when there are low levels of acetyl CoA in the body?

<p>Pyruvate is oxidized by the PDH complex (D)</p> Signup and view all the answers

What is the function of the TCA cycle?

<p>To produce ATP (C)</p> Signup and view all the answers

What accumulates when there is a high level of acetyl CoA in the body?

<p>OAA (B)</p> Signup and view all the answers

What happens when Pyruvate Carboxylase is inactive?

<p>TCA cycle is activated (D)</p> Signup and view all the answers

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