29 Questions
Which process depletes oxaloacetate (OAA) and prevents acetyl CoA entry into Krebs Cycle?
Gluconeogenesis
What happens if oxaloacetate (OAA) is depleted in the TCA cycle?
TCA cycle stops
What activates Pyruvate Carboxylase allosterically?
Acetyl CoA
What determines the entry of Acetyl CoA into Krebs cycle?
OAA availability
What happens when acetyl CoA accumulates in the cell?
Pyruvate Carboxylase is activated
What happens when acetyl CoA levels are low in the cell?
Pyruvate is primarily oxidized by PDH complex
Which enzyme is responsible for synthesizing oxaloacetate (OAA) in the cell?
Pyruvate Carboxylase
What is the effect of OAA depletion on the TCA cycle?
TCA cycle stops
What is the effect of acetyl CoA accumulation on Pyruvate Carboxylase activity?
Activates Pyruvate Carboxylase
Which process depletes oxaloacetate (OAA) and prevents acetyl CoA entry into Krebs Cycle?
Gluconeogenesis
What happens if oxaloacetate (OAA) is depleted in the TCA cycle?
TCA cycle stops
What activates Pyruvate Carboxylase allosterically?
Acetyl CoA
What determines the entry of Acetyl CoA into Krebs cycle?
OAA availability
What happens when acetyl CoA accumulates in the cell?
Pyruvate Carboxylase is activated
What happens when acetyl CoA levels are low in the cell?
Pyruvate is primarily oxidized by PDH complex
Which enzyme is responsible for synthesizing oxaloacetate (OAA) in the cell?
Pyruvate Carboxylase
What is the role of OAA in the TCA cycle?
Provides OAA to the TCA cycle
What is the effect of OAA depletion on the TCA cycle?
TCA cycle stops
What is the effect of acetyl CoA accumulation on Pyruvate Carboxylase activity?
Activates Pyruvate Carboxylase
What is the primary purpose of oxaloacetate (OAA) synthesis?
To synthesize glucose
What happens if OAA is depleted in the body?
TCA cycle will stop
What is the role of Pyruvate Carboxylase in the body?
To synthesize glucose
What activates Pyruvate Carboxylase?
Acetyl CoA
What determines the entry of Acetyl CoA into the Krebs cycle?
The availability of OAA
What depletes OAA in the body?
Gluconeogenesis
What happens when there are low levels of acetyl CoA in the body?
Pyruvate is oxidized by the PDH complex
What is the function of the TCA cycle?
To produce ATP
What accumulates when there is a high level of acetyl CoA in the body?
OAA
What happens when Pyruvate Carboxylase is inactive?
TCA cycle is activated
Test your knowledge on the critical role of oxaloacetate (OAA) synthesis in metabolic pathways such as gluconeogenesis and the TCA cycle. Learn about the importance of OAA availability in determining the entry of Acetyl CoA into the Krebs cycle and how Pyruvate Carboxylase is activated by acetyl CoA. Take this quiz to deepen your understanding of the complex interplay between OAA, acetyl CoA, and metabolic pathways.
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