Mastering the Role of Oxaloacetate (OAA) in Metabolic Pathways Quiz
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Questions and Answers

Which process depletes oxaloacetate (OAA) and prevents acetyl CoA entry into Krebs Cycle?

  • Glycolysis
  • Gluconeogenesis (correct)
  • Beta-oxidation
  • Fatty acid synthesis
  • What happens if oxaloacetate (OAA) is depleted in the TCA cycle?

  • PDH complex is activated
  • Pyruvate Carboxylase is activated
  • TCA cycle stops (correct)
  • Gluconeogenesis stops
  • What activates Pyruvate Carboxylase allosterically?

  • ATP
  • Oxaloacetate
  • Pyruvate
  • Acetyl CoA (correct)
  • What determines the entry of Acetyl CoA into Krebs cycle?

    <p>OAA availability</p> Signup and view all the answers

    What happens when acetyl CoA accumulates in the cell?

    <p>Pyruvate Carboxylase is activated</p> Signup and view all the answers

    What happens when acetyl CoA levels are low in the cell?

    <p>Pyruvate is primarily oxidized by PDH complex</p> Signup and view all the answers

    Which enzyme is responsible for synthesizing oxaloacetate (OAA) in the cell?

    <p>Pyruvate Carboxylase</p> Signup and view all the answers

    What is the effect of OAA depletion on the TCA cycle?

    <p>TCA cycle stops</p> Signup and view all the answers

    What is the effect of acetyl CoA accumulation on Pyruvate Carboxylase activity?

    <p>Activates Pyruvate Carboxylase</p> Signup and view all the answers

    Which process depletes oxaloacetate (OAA) and prevents acetyl CoA entry into Krebs Cycle?

    <p>Gluconeogenesis</p> Signup and view all the answers

    What happens if oxaloacetate (OAA) is depleted in the TCA cycle?

    <p>TCA cycle stops</p> Signup and view all the answers

    What activates Pyruvate Carboxylase allosterically?

    <p>Acetyl CoA</p> Signup and view all the answers

    What determines the entry of Acetyl CoA into Krebs cycle?

    <p>OAA availability</p> Signup and view all the answers

    What happens when acetyl CoA accumulates in the cell?

    <p>Pyruvate Carboxylase is activated</p> Signup and view all the answers

    What happens when acetyl CoA levels are low in the cell?

    <p>Pyruvate is primarily oxidized by PDH complex</p> Signup and view all the answers

    Which enzyme is responsible for synthesizing oxaloacetate (OAA) in the cell?

    <p>Pyruvate Carboxylase</p> Signup and view all the answers

    What is the role of OAA in the TCA cycle?

    <p>Provides OAA to the TCA cycle</p> Signup and view all the answers

    What is the effect of OAA depletion on the TCA cycle?

    <p>TCA cycle stops</p> Signup and view all the answers

    What is the effect of acetyl CoA accumulation on Pyruvate Carboxylase activity?

    <p>Activates Pyruvate Carboxylase</p> Signup and view all the answers

    What is the primary purpose of oxaloacetate (OAA) synthesis?

    <p>To synthesize glucose</p> Signup and view all the answers

    What happens if OAA is depleted in the body?

    <p>TCA cycle will stop</p> Signup and view all the answers

    What is the role of Pyruvate Carboxylase in the body?

    <p>To synthesize glucose</p> Signup and view all the answers

    What activates Pyruvate Carboxylase?

    <p>Acetyl CoA</p> Signup and view all the answers

    What determines the entry of Acetyl CoA into the Krebs cycle?

    <p>The availability of OAA</p> Signup and view all the answers

    What depletes OAA in the body?

    <p>Gluconeogenesis</p> Signup and view all the answers

    What happens when there are low levels of acetyl CoA in the body?

    <p>Pyruvate is oxidized by the PDH complex</p> Signup and view all the answers

    What is the function of the TCA cycle?

    <p>To produce ATP</p> Signup and view all the answers

    What accumulates when there is a high level of acetyl CoA in the body?

    <p>OAA</p> Signup and view all the answers

    What happens when Pyruvate Carboxylase is inactive?

    <p>TCA cycle is activated</p> Signup and view all the answers

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