Mastering the Mechanism

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20 Questions

Match the following medications with their mode of action:

SSRIs = Inhibits the reuptake of 5HT2 (serotonin) SNRIs = Inhibits the reuptake of 5HT2 (serotonin) and NA (noradrenaline) TCAs = Inhibits the reuptake of 5HT2 (serotonin), NA (noradrenaline), and DA (dopamine) MOA-Is = Inhibits, non-selectively and irreversibly, 5HT2 (serotonin), DA (dopamine), NA (noradrenaline), and Adrenaline

Match the following medications with their cautions:

SSRIs = Pregnancy Category C, Sodium levels, Serotonin syndrome, Bleeding issues SNRIs = Pregnancy Category C, Sodium levels, Serotonin syndrome, Bleeding issues, Heart issues TCAs = Elderly issues, Seizure issues, Hepatic issues, Pregnancy Category C, Toxic in overdose (not for the suicidal) MOA-Is = Seizure issues, Diabetic issues, Pregnancy (no data), Elderly (cardiac), Tyramine, Hypotension

Match the following disorders with their corresponding medications:

Major Depression Disorder = SSRIs, SNRIs, TCAs, MOA-Is Bipolar Disorder = Lithium Sleep Disorders = Melatonin and Zolpidem

Match the following medications with their usage in pregnancy:

SSRIs = Category C SNRIs = Category C TCAs = Category C MOA-Is = Pregnancy (no data)

Match the following medications with their effects on neurotransmitters:

SSRIs = Inhibits the reuptake of 5HT2 (serotonin) SNRIs = Inhibits the reuptake of 5HT2 (serotonin) and NA (noradrenaline) TCAs = Inhibits the reuptake of 5HT2 (serotonin), NA (noradrenaline), and DA (dopamine) MOA-Is = Inhibits, non-selectively and irreversibly, 5HT2 (serotonin), DA (dopamine), NA (noradrenaline), and Adrenaline

Match the following medications with their cautions for the elderly:

SSRIs = None SNRIs = None TCAs = Elderly issues MOA-Is = Elderly (cardiac)

Match the following medications with their cautions for seizure issues:

SSRIs = None SNRIs = None TCAs = Seizure issues MOA-Is = Seizure issues

Match the following medications with their cautions for hepatic issues:

SSRIs = None SNRIs = None TCAs = Hepatic issues MOA-Is = Diabetic issues, Hepatic

Match the following medications with their cautions for sodium levels:

SSRIs = Sodium levels SNRIs = Sodium levels TCAs = None MOA-Is = None

Match the following medications with their cautions for bleeding issues:

SSRIs = Bleeding issues SNRIs = Bleeding issues TCAs = None MOA-Is = None

Match the following medications with their modes of action:

Risperidone = Antagonism of DA2 and 5HT2A ACE Inhibitors = Blocks the conversion of Angiotensin I to Angiotensin II Calcium Channel Blockers = Blocks the inward current of calcium in vascular muscles Statins = Stops the body from making excess cholesterol and increases cholesterol uptake in the liver

Match the following medications with their cautions:

Risperidone = Parkinson's, Dementia, Seizures, Lactation Sartans = More effective to add a second agent if it doesn’t work, Lactation, Renal, Geriatric, Potassium-increasing drugs, NSAIDs, Diuretics Calcium Channel Blockers = Lactation, Hepatic, Geriatric, Avoid Beta Blockers, Systolic Heart Failure Thiazide Diuretics = Avoid in pregnancy, Hepatic, Geriatric, NSAIDs, Potassium-decreasing drugs, Renal

Match the following medications with their uses:

Thiazide Diuretics = For mild to moderate hypertension and edema Statins = Stops the body from making excess cholesterol and increases cholesterol uptake in the liver Ezetimibe = Decreases the body’s absorption of cholesterol Risperidone = Antipsychotic

Match the following medication classes with their suffixes:

Antipsychotics = -apine Hypertension Medications = -pril Sartans = -sartan Calcium Channel Blockers = -ipine

Match the following medication classes with their modes of action:

Antipsychotics = Antagonism of DA2 and 5HT2A Hypertension Medications = Blocks the conversion of Angiotensin I to Angiotensin II Calcium Channel Blockers = Blocks the inward current of calcium in vascular muscles Dyslipidaemia = Stops the body from making excess cholesterol and increases cholesterol uptake in the liver

Match the following medication classes with their cautions:

Antipsychotics = Parkinson's, Dementia, Seizures, Lactation Hypertension Medications = Lactation, Renal, Geriatric, Potassium-increasing drugs, NSAIDs, Diuretics Calcium Channel Blockers = Lactation, Hepatic, Geriatric, Avoid Beta Blockers, Systolic Heart Failure Thiazide Diuretics = Avoid in pregnancy, Hepatic, Geriatric, NSAIDs, Potassium-decreasing drugs, Renal

Match the following medication classes with their uses:

Thiazide Diuretics = For mild to moderate hypertension and edema Statins = Stops the body from making excess cholesterol and increases cholesterol uptake in the liver Ezetimibe = Decreases the body’s absorption of cholesterol Antipsychotics = Treatment of psychotic disorders

Match the following medication suffixes with their classes:

-apine = Antipsychotics -pril = ACE Inhibitors -sartan = Sartans -ipine = Calcium Channel Blockers

Match the following medication modes of action with their classes:

Antagonism of DA2 and 5HT2A = Antipsychotics Blocks the conversion of Angiotensin I to Angiotensin II = Hypertension Medications Blocks the inward current of calcium in vascular muscles = Calcium Channel Blockers Stops the body from making excess cholesterol and increases cholesterol uptake in the liver = Dyslipidaemia

Match the following medication cautions with their classes:

Parkinson's, Dementia, Seizures, Lactation = Antipsychotics Lactation, Renal, Geriatric, Potassium-increasing drugs, NSAIDs, Diuretics = Hypertension Medications Lactation, Hepatic, Geriatric, Avoid Beta Blockers, Systolic Heart Failure = Calcium Channel Blockers Avoid in pregnancy, Hepatic, Geriatric, NSAIDs, Potassium-decreasing drugs, Renal = Thiazide Diuretics

Test your knowledge on the mode of action and cautions of SSRIs, SNRIs, TCAs, and MOA-Is in the treatment of Major Depression Disorder. Learn about how these medications inhibit the reuptake of serotonin and noradrenaline, and the potential risks associated with their use.

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