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Mastering Regulatory T Cells
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Mastering Regulatory T Cells

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Questions and Answers

Which cytokine is involved in the generation of regulatory T cells by stimulating the expression of the FoxP3 transcription factor?

  • IL-2
  • TGF-β (correct)
  • CTLA-4
  • IL-10

    • What is one of the mechanisms by which regulatory T cells suppress immune responses?

  • Blocking B7 molecules
  • Producing IL-2
  • Expressing CTLA-4
  • Consuming TGF-β (correct)

    • What is the main interest in regulatory T cells in relation to autoimmune diseases?

  • Defective regulation of regulatory T cells
  • Resistance of pathogenic T cells to regulation
  • Both A and B (correct)
  • None of the above

    • Which transcription factor is required for the development and function of regulatory T cells?

    <p>FoxP3</p> Signup and view all the answers

    What is the acronym for the autoimmune disease caused by mutations in the gene encoding FoxP3?

    <p>IPEX</p> Signup and view all the answers

    Which cytokine is required for the survival and function of regulatory T cells?

    <p>IL-2</p> Signup and view all the answers

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