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Questions and Answers
Which cytokine is involved in the generation of regulatory T cells by stimulating the expression of the FoxP3 transcription factor?
Which cytokine is involved in the generation of regulatory T cells by stimulating the expression of the FoxP3 transcription factor?
- IL-2
- TGF-β (correct)
- CTLA-4
- IL-10
What is one of the mechanisms by which regulatory T cells suppress immune responses?
What is one of the mechanisms by which regulatory T cells suppress immune responses?
- Blocking B7 molecules
- Producing IL-2
- Expressing CTLA-4
- Consuming TGF-β (correct)
What is the main interest in regulatory T cells in relation to autoimmune diseases?
What is the main interest in regulatory T cells in relation to autoimmune diseases?
- Defective regulation of regulatory T cells
- Resistance of pathogenic T cells to regulation
- Both A and B (correct)
- None of the above
Which transcription factor is required for the development and function of regulatory T cells?
Which transcription factor is required for the development and function of regulatory T cells?
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What is the acronym for the autoimmune disease caused by mutations in the gene encoding FoxP3?
What is the acronym for the autoimmune disease caused by mutations in the gene encoding FoxP3?
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Which cytokine is required for the survival and function of regulatory T cells?
Which cytokine is required for the survival and function of regulatory T cells?
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