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Mastering MHC
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Mastering MHC

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Questions and Answers

Hangisi MHC moleküllerinin yapısında bulunmayan bir özelliktir?

  • Peptit baÄŸlama oluÄŸunun amino ucu
  • Farklı zincirlerden oluÅŸması
  • Antijen sunumunu T lenfositlerine saÄŸlaması
  • Dendritik hücrelerde en profesyonel olması (correct)
  • Hangisi doÄŸrudur?

  • T lenfositleri, antijen sunan hücreler tarafından sunulan peptid formundaki protein antijenlerini tanır. (correct)
  • Sadece dendritik hücreler antijen sunan hücrelerdir.
  • MHC sınıf 1 ve 2 molekülleri farklı yapıya sahip deÄŸillerdir.
  • MHC molekülleri, protein antijenleri tanımlama iÅŸlevi dışında herhangi bir fizyolojik iÅŸlevi yoktur.
  • Hangisi yanlıştır?

  • MHC genleri, MHC proteinlerini kodlayan bir dizi gen koleksiyonudur.
  • MHC sınıf 1 ve 2 molekülleri, farklı zincirlerden oluÅŸur.
  • MHC molekülleri, antijen sunan hücreler tarafından sunulan peptid antijenleri tanımlama iÅŸlevi görür.
  • MHC locus, sadece insanlarda HLA genlerini içerir. (correct)
  • Hangisi doÄŸrudur?

    <p>MHC sınıf 1 ve 2 molekülleri, amino uçta peptid bağlama yuvasına sahiptir.</p> Signup and view all the answers

    Study Notes

    • MHC Class 1 molecule has 3 domains: alpha1, alpha2, alpha3.
    • Peptide binding groove in MHC Class 1 molecule recognizes 8-9 amino acid antigens.
    • MHC Class 1 molecule can recognize different peptides, but only one at a time.
    • MHC Class 2 molecule has two chains: alpha(1,2) and beta(1,2).
    • Alpha1 and beta1 chains form the polymorphic region in MHC Class 2 molecule.
    • MHC Class 1 molecule is composed of alpha chain and beta2-microglobulin.
    • Beta2-microglobulin binds to alpha chain through non-covalent bonds.
    • Peptide binding groove in MHC Class 1 molecule can accommodate 8-9 amino acid peptides.
    • T lymphocytes recognize peptides bound to the base of the peptide binding groove.
    • T cell receptor binds to both the antigen and MHC molecule in the peptide binding groove.

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    Description

    Test your knowledge on MHC molecules and their role in immune response with this quiz! From the domains of MHC Class 1 to the polymorphic region of MHC Class 2, this quiz covers the basics of MHC structure and function. See how much you know about peptide binding grooves, T lymphocytes, and T cell receptors. Keywords: MHC Class 1, MHC Class 2, alpha chain, beta2-microglobulin, peptide binding groove, T lymph

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