Mastering A&P Chapter 9 - Muscle Tissue Quiz
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Questions and Answers

The cross bridge cycle starts when ________.

Ca2+ from the sarcoplasmic reticulum binds to troponin

Place the steps that occur during a single cross bridge cycle in the correct order from left to right.

  • Activated myosin head binds to actin, forming a cross bridge. (correct)
  • ATP is hydrolyzed to ADP and Pi and the energy released re-cocks the myosin head. (correct)
  • ATP binds to the myosin head and detaches it from actin. (correct)
  • ADP is released and myosin slides the thin filament toward the center of the sarcomere. (correct)

What is myosin?

Myofilament with a knob-like head

What is actin?

<p>Myofilament stiffened and stabilized by tropomyosin</p> Signup and view all the answers

What is sarcoplasm?

<p>The cytoplasm of a skeletal muscle fiber</p> Signup and view all the answers

What is a fascicle?

<p>Bundle of skeletal muscle fibers enclosed by connective tissue called perimysium</p> Signup and view all the answers

What is the sarcolemma?

<p>Membrane of muscle cell</p> Signup and view all the answers

What blocks myosin-binding sites on actin?

<p>Tropomyosin</p> Signup and view all the answers

What are skeletal muscle fibers?

<p>Long, cylindrical cells</p> Signup and view all the answers

What is a sarcomere?

<p>Contractile unit</p> Signup and view all the answers

What are myofibrils?

<p>Made up of several sarcomeres</p> Signup and view all the answers

In the event that a muscle cell runs out of ATP, what step of the cross bridge cycle is most directly inhibited or terminated?

<p>Cross bridge detachment (A)</p> Signup and view all the answers

What best explains rigor mortis after death?

<p>Cross bridge detachment cannot occur. (C)</p> Signup and view all the answers

Flashcards

Cross Bridge Cycle Initiation

Starts when Ca2+ binds to troponin.

Role of Calcium

Elevated Ca2+ causes troponin to move tropomyosin away from actin's binding sites.

Cross Bridge Formation

Myosin heads bind to actin, forming a link between filaments.

Power Stroke

Sliding of thin filament toward the sarcomere's center.

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Cross Bridge Detachment

ATP binding to myosin, causes myosin to detach from actin.

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Myosin Head Re-cocking

Hydrolyzes ATP into ADP and Pi

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Myosin

Myofilament with a knob-like head; essential for muscle contraction.

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Actin

Myofilament stabilized by tropomyosin; forms thin filaments.

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Sarcoplasm

Cytoplasm within skeletal muscle fibers.

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Fascicle

Bundles of muscle fibers encased in perimysium.

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Sarcolemma

Plasma membrane surrounding muscle cells.

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Sarcomere

Fundamental contractile unit of striated muscle.

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Tropomyosin

Blocks myosin-binding sites on actin when muscle is relaxed.

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Study Notes

Cross Bridge Cycle Initiation

  • The cross bridge cycle begins when Ca2+ from the sarcoplasmic reticulum binds to troponin.
  • Elevated Ca2+ levels cause a conformational change in troponin, moving tropomyosin away from actin's myosin-binding sites.

Steps in the Cross Bridge Cycle

  • Myosin heads bind to actin, forming a cross bridge.
  • Release of ADP results in the "power stroke," sliding the thin filament towards the sarcomere's center.
  • ATP binds to myosin, prompting detachment from actin.
  • ATP is hydrolyzed into ADP and inorganic phosphate (Pi), re-cocking the myosin head.
  • The cycle continues as long as calcium ions and ATP are present, leading to muscle contraction.

Muscle Fiber Structure

  • Myosin: Myofilament characterized by a knob-like head, essential for muscle contraction.
  • Actin: Myofilament that is stabilized by tropomyosin, forming the structure of thin filaments.
  • Sarcoplasm: The cytoplasm within skeletal muscle fibers, containing necessary organelles and proteins.
  • Fascicle: Bundles of muscle fibers encased in connective tissue known as perimysium.
  • Sarcolemma: The plasma membrane surrounding muscle cells, crucial for maintaining ionic gradients.

Sarcomere and Myofilaments

  • Sarcomere: The fundamental contractile unit of striated muscle, comprising alternating thick (myosin) and thin (actin) filaments.
  • Myofibrils: Structures made of aligned sarcomeres that run the length of the muscle fiber, facilitating contraction.

Tropomyosin and Muscle Contraction

  • Tropomyosin blocks the myosin-binding sites on actin when muscle fibers are relaxed, preventing contraction.

Physiological Responses

  • Cross bridge detachment is significantly hindered when ATP levels drop, leading to muscle stiffness.
  • In rigor mortis, calcium leaks into the cytoplasm post-mortem, resulting in sustained contraction due to the absence of ATP for detachment.

Important Facts About Cross Bridge Cycling

  • Detachment requires ATP, thus lacking ATP halts the cycle and maintains cross bridges.
  • During cycling, only half of myosin heads detach at any time while calcium is available.
  • Myosin is in an energized state with ADP and Pi bound before the cross bridge cycle initiates.

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Description

Test your knowledge on the cross bridge cycle and muscle physiology with this quiz based on Chapter 9 of Mastering Anatomy & Physiology. Understand key concepts including calcium ion dynamics and muscle contraction. Perfect for students seeking to reinforce their understanding of this essential topic.

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