Mastering Gram-Positive Bacilli
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Questions and Answers

Which of the following is a characteristic of Corynebacterium?

  • Gram-positive (correct)
  • Motile
  • Catalase negative
  • Spore-forming
  • Which species of Corynebacterium causes diphtheria?

  • C.hemolyticum
  • C.ulcerans
  • C.diphtheriae (correct)
  • C.jeikium
  • What is the major infection caused by C.diphtheriae?

  • Endocarditis
  • Respiratory diphtheria (correct)
  • Pharyngitis
  • Cutaneous diphtheria
  • How is diphtheria diagnosed in the laboratory?

    <p>Nasopharyngeal swab</p> Signup and view all the answers

    What type of stain is used to visualize Corynebacterium in the laboratory?

    <p>Albert's stain</p> Signup and view all the answers

    Which selective media is used to differentiate commensal species from C. diphtheriae?

    <p>Hoyle's Tellurite blood agar</p> Signup and view all the answers

    What is the purpose of using tellurite salt in Hoyle's Tellurite blood agar?

    <p>To produce a dark halo around C. diphtheriae colonies</p> Signup and view all the answers

    Which biochemical test is used for the identification of C. ulcerans?

    <p>Hiss's Serum sugars</p> Signup and view all the answers

    What is the mainstay of treatment for diphtheria?

    <p>Antidiphtheritic serum</p> Signup and view all the answers

    Which antibiotics are sensitive to C. diphtheriae?

    <p>Erythromycin, Penicillin, Clindamycin</p> Signup and view all the answers

    Study Notes

    Characteristics of Corynebacterium

    • Corynebacterium species possess characteristic club-shaped or filamentous morphology

    Diphtheria and C. diphtheriae

    • C. diphtheriae causes diphtheria
    • Diphtheria is the major infection caused by C. diphtheriae

    Laboratory Diagnosis of Diphtheria

    • Diphtheria is diagnosed in the laboratory through laboratory tests
    • Palkovac or Loeffler's medium is used to visualize Corynebacterium in the laboratory
    • Tellurite agar or Hoyle's Tellurite blood agar is used to differentiate commensal species from C. diphtheriae
    • Tellurite salt in Hoyle's Tellurite blood agar inhibits growth of other bacteria, allowing selective growth of C. diphtheriae

    Identification of C. ulcerans

    • C. ulcerans is identified through a biochemical test, such as the Elek test

    Treatment of Diphtheria

    • The mainstay of treatment for diphtheria is antitoxin administration
    • Antibiotics such as erythromycin and penicillin are sensitive to C. diphtheriae

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    Description

    Test your knowledge on Gram-positive bacilli with this quiz! Learn about the general characteristics of Corynebacterium, including their morphology, presence of metachromatic granules, and their other common name, the Klebs-Löffler bacillus.

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