14 Questions
Which drug serves as an indirect antagonist for the PCP binding site of the NMDA receptor?
Phencyclidine
What is the most important inhibitory neurotransmitter in the brain?
Gamma-Aminobutyric Acid (GABA)
Which drug category serves as an indirect agonist for the GABAA receptor?
Benzodiazepine
Which of the following is NOT a factor that determines the level of drug addiction?
Rate of clearance from body
What is the primary difference between opiates and opioids?
Opiates are derived from the poppy plant while opioids are synthetic drugs
Which route of administration involves injection of a substance directly into a vein?
Intravenous (IV) Injection
Which neurotransmitter is synthesized from L-DOPA and plays a role in movement, reinforcement/reward, and short-term memory?
Dopamine
Which drug inhibits the reuptake of dopamine?
Methylphenidate
Which neurotransmitter is found in the brain and the sympathetic division of the ANS, and also serves as a hormone secreted by the adrenal medulla?
Norepinephrine
Which neurotransmitter regulates mood, appetite, and sleep?
Serotonin
Which route of administration involves placing a substance beneath the tongue?
Sublingual administration
What is the therapeutic index?
The ratio between the dose that produces the harmful effect in 50% of the animals and the dose that produces desirable effects in 50% of the animals.
What is tolerance?
A decrease in the effectiveness of a drug that is administered repeatedly.
What is an agonist?
A drug that facilitates the effects of a particular neurotransmitter on the postsynaptic cell.
Test your knowledge on dopamine, a neurotransmitter and neuromodulator in the brain. Learn about its synthesis, major CNS systems, and roles in movement, reinforcement, and reward.
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