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Questions and Answers
Which protein undergoes a conformational change after binding to the CD4 molecule?
Which protein undergoes a conformational change after binding to the CD4 molecule?
- DC-SIGN
- CXCR4
- gp120 (correct)
- CCR5
What is the function of the pre-integration complex?
What is the function of the pre-integration complex?
- Fusion with the host cell membrane
- Facilitating reverse transcription (correct)
- Formation of the pre-integration complex
- Uncoating the capsid protein shell
Which molecule facilitates cell-to-cell spread of HIV?
Which molecule facilitates cell-to-cell spread of HIV?
- CXCR4
- CCR5
- CD4
- DC-SIGN (correct)
What is the role of the gp41 molecule during fusion with the host cell membrane?
What is the role of the gp41 molecule during fusion with the host cell membrane?
What are the two major co-receptors that the gp120 protein can bind to?
What are the two major co-receptors that the gp120 protein can bind to?
Which gene in the HIV-1 genome encodes the proteins responsible for forming the core of the virion?
Which gene in the HIV-1 genome encodes the proteins responsible for forming the core of the virion?
What is the main function of the POL gene in the HIV-1 genome?
What is the main function of the POL gene in the HIV-1 genome?
Which gene in the HIV-1 genome encodes the envelope glycoproteins?
Which gene in the HIV-1 genome encodes the envelope glycoproteins?
Which regulatory genes are present in HIV-1?
Which regulatory genes are present in HIV-1?
Which gene is lacking in HIV-2 compared to HIV-1?
Which gene is lacking in HIV-2 compared to HIV-1?
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