10 Questions
Which protein undergoes a conformational change after binding to the CD4 molecule?
gp120
What is the function of the pre-integration complex?
Facilitating reverse transcription
Which molecule facilitates cell-to-cell spread of HIV?
DC-SIGN
What is the role of the gp41 molecule during fusion with the host cell membrane?
Coiling upon itself
What are the two major co-receptors that the gp120 protein can bind to?
CCR5 and CXCR4
Which gene in the HIV-1 genome encodes the proteins responsible for forming the core of the virion?
GAG gene
What is the main function of the POL gene in the HIV-1 genome?
Processing viral proteins
Which gene in the HIV-1 genome encodes the envelope glycoproteins?
ENV gene
Which regulatory genes are present in HIV-1?
tat, rev, nef, vif, vpr, and vpu
Which gene is lacking in HIV-2 compared to HIV-1?
vpu gene
Test your knowledge on the replication cycle of HIV, including the initial binding process involving the gp120 protein, CD4 molecule, and co-receptors CCR5 and CXCR4. Learn about the crucial steps involved in the cell-to-cell spread of the virus.
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