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Questions and Answers
Which of the following is the primary indication for antidepressant agents?
Which of the following is the primary indication for antidepressant agents?
- Treatment of schizophrenia
- Treatment of anxiety disorders
- Treatment of major depressive disorder (correct)
- Treatment of bipolar disorder
According to the Centers for Disease Control and Prevention, what were the most commonly prescribed medications in the USA?
According to the Centers for Disease Control and Prevention, what were the most commonly prescribed medications in the USA?
- Antipsychotic drugs
- Antidepressant drugs (correct)
- Antibiotics
- Antiepileptic drugs
What is the lifetime prevalence of major depression in the USA?
What is the lifetime prevalence of major depression in the USA?
- Around 5%
- Around 25%
- Around 10%
- Around 17% (correct)
What is the point prevalence of major depression in the USA?
What is the point prevalence of major depression in the USA?
According to the learning objectives, which classes of antidepressant drugs are listed?
According to the learning objectives, which classes of antidepressant drugs are listed?
What is the primary cellular target of antidepressant drugs?
What is the primary cellular target of antidepressant drugs?
Which of the following is a common side effect of tricyclic antidepressants (TCAs)?
Which of the following is a common side effect of tricyclic antidepressants (TCAs)?
Which of the following is a characteristic of tertiary TCAs?
Which of the following is a characteristic of tertiary TCAs?
Which of the following is a side effect of nefazodone?
Which of the following is a side effect of nefazodone?
Which of the following is a characteristic of trazodone?
Which of the following is a characteristic of trazodone?
Which of the following is an example of a heterocyclic tetracyclic antidepressant?
Which of the following is an example of a heterocyclic tetracyclic antidepressant?
Which of the following is a characteristic of amoxapine?
Which of the following is a characteristic of amoxapine?
Which of the following is NOT a disorder for which antidepressants have received FDA approval?
Which of the following is NOT a disorder for which antidepressants have received FDA approval?
Which hypothesis suggests that a deficit in function or amount of monoamines is central to the biology of depression?
Which hypothesis suggests that a deficit in function or amount of monoamines is central to the biology of depression?
Which mechanism is shared by almost all antidepressants?
Which mechanism is shared by almost all antidepressants?
Which class of antidepressant drugs inhibits the enzymatic degradation of monoamines?
Which class of antidepressant drugs inhibits the enzymatic degradation of monoamines?
Which selective serotonin reuptake inhibitor (SSRI) has the longest half-life?
Which selective serotonin reuptake inhibitor (SSRI) has the longest half-life?
Which antidepressant class has relatively long half-lives ranging from 18 to 70 hours?
Which antidepressant class has relatively long half-lives ranging from 18 to 70 hours?
Which of the following is a common side effect of Selective Serotonin Reuptake Inhibitors (SSRIs)?
Which of the following is a common side effect of Selective Serotonin Reuptake Inhibitors (SSRIs)?
Which SSRI has a long half-life and a decreased incidence of discontinuation syndromes?
Which SSRI has a long half-life and a decreased incidence of discontinuation syndromes?
Which of the following can be a disadvantage of fluoxetine due to its long half-life?
Which of the following can be a disadvantage of fluoxetine due to its long half-life?
Which class of antidepressants inhibits both serotonin and noradrenergic reuptake?
Which class of antidepressants inhibits both serotonin and noradrenergic reuptake?
Which SNRI has minimal drug interactions and almost no P450 activity?
Which SNRI has minimal drug interactions and almost no P450 activity?
Which SNRI is indicated for major depressive disorder, diabetic peripheral neuropathic pain, and generalized anxiety disorder?
Which SNRI is indicated for major depressive disorder, diabetic peripheral neuropathic pain, and generalized anxiety disorder?
Which of the following is a characteristic of bupropion?
Which of the following is a characteristic of bupropion?
What is the mechanism by which bupropion enhances the ability of patients to abstain from smoking?
What is the mechanism by which bupropion enhances the ability of patients to abstain from smoking?
Which of the following is a characteristic of mirtazapine?
Which of the following is a characteristic of mirtazapine?
What is a potential side effect of mirtazapine?
What is a potential side effect of mirtazapine?
Which of the following is true about monoamine oxidase inhibitors (MAOIs)?
Which of the following is true about monoamine oxidase inhibitors (MAOIs)?
What can happen if MAOIs are taken with tyramine-rich foods or sympathomimetics?
What can happen if MAOIs are taken with tyramine-rich foods or sympathomimetics?
Which of the following is NOT a major class of antidepressant drugs?
Which of the following is NOT a major class of antidepressant drugs?
Which of the following is a primary cellular target of antidepressant drugs?
Which of the following is a primary cellular target of antidepressant drugs?
Which of the following is a common therapeutic indication for antidepressant drugs?
Which of the following is a common therapeutic indication for antidepressant drugs?
Which of the following is a common adverse effect of classical antidepressants?
Which of the following is a common adverse effect of classical antidepressants?
Which of the following is a potential interaction of St. John's wort with other antidepressant drugs?
Which of the following is a potential interaction of St. John's wort with other antidepressant drugs?
What is the prevalence of major depression in the USA?
What is the prevalence of major depression in the USA?
Which of the following is a common side effect of Selective Serotonin Reuptake Inhibitors (SSRIs)?
Which of the following is a common side effect of Selective Serotonin Reuptake Inhibitors (SSRIs)?
Which SNRI has minimal drug interactions and almost no P450 activity?
Which SNRI has minimal drug interactions and almost no P450 activity?
What is a potential side effect of mirtazapine?
What is a potential side effect of mirtazapine?
Which SSRI has a long half-life and a decreased incidence of discontinuation syndromes?
Which SSRI has a long half-life and a decreased incidence of discontinuation syndromes?
Which of the following is a characteristic of bupropion?
Which of the following is a characteristic of bupropion?
Which of the following is a characteristic of trazodone?
Which of the following is a characteristic of trazodone?
Which of the following is a side effect of tricyclic antidepressants (TCAs)?
Which of the following is a side effect of tricyclic antidepressants (TCAs)?
Which of the following is a potential serious side effect of tricyclic antidepressants (TCAs)?
Which of the following is a potential serious side effect of tricyclic antidepressants (TCAs)?
Which of the following antidepressants is associated with priapism as a serious side effect?
Which of the following antidepressants is associated with priapism as a serious side effect?
Which of the following antidepressants is a weak inhibitor of both serotonin and norepinephrine reuptake?
Which of the following antidepressants is a weak inhibitor of both serotonin and norepinephrine reuptake?
Which of the following antidepressants is a metabolite of Loxapine and retains some antipsychotic activity?
Which of the following antidepressants is a metabolite of Loxapine and retains some antipsychotic activity?
Which of the following antidepressants is primarily used for unipolar depression, anxiety disorder, and insomnia?
Which of the following antidepressants is primarily used for unipolar depression, anxiety disorder, and insomnia?
Which of the following is a characteristic of selective serotonin reuptake inhibitors (SSRIs)?
Which of the following is a characteristic of selective serotonin reuptake inhibitors (SSRIs)?
Which of the following is NOT a mechanism of action for most antidepressants?
Which of the following is NOT a mechanism of action for most antidepressants?
Which class of antidepressant drugs has the highest potential for drug interactions?
Which class of antidepressant drugs has the highest potential for drug interactions?
Which of the following is a characteristic of tricyclic antidepressants (TCAs)?
Which of the following is a characteristic of tricyclic antidepressants (TCAs)?
Which hypothesis suggests that neurotrophic and endocrine factors play a major role in the pathophysiology of major depression?
Which hypothesis suggests that neurotrophic and endocrine factors play a major role in the pathophysiology of major depression?
Which of the following is a characteristic of monoamine oxidase inhibitors (MAOIs)?
Which of the following is a characteristic of monoamine oxidase inhibitors (MAOIs)?
Which of the following is a characteristic of bupropion?
Which of the following is a characteristic of bupropion?
Which of the following is a characteristic of mirtazapine?
Which of the following is a characteristic of mirtazapine?
What can happen if monoamine oxidase inhibitors (MAOIs) are taken with tyramine-rich foods or sympathomimetics?
What can happen if monoamine oxidase inhibitors (MAOIs) are taken with tyramine-rich foods or sympathomimetics?
Which of the following is a side effect of mirtazapine?
Which of the following is a side effect of mirtazapine?
Which of the following is a characteristic of tetracyclic antidepressants?
Which of the following is a characteristic of tetracyclic antidepressants?
Which of the following is a characteristic of selective serotonin reuptake inhibitors (SSRIs)?
Which of the following is a characteristic of selective serotonin reuptake inhibitors (SSRIs)?
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