Podcast
Questions and Answers
Which of the following is the correct sequence of events in synaptic transmission?
Which of the following is the correct sequence of events in synaptic transmission?
- Calcium ions flood into the terminal button, vesicles fuse with the presynaptic membrane, action potential depolarizes the membrane
- Action potential depolarizes the membrane, calcium ions flood into the terminal button, vesicles fuse with the presynaptic membrane (correct)
- Vesicles fuse with the presynaptic membrane, action potential depolarizes the membrane, calcium ions flood into the terminal button
- Vesicles fuse with the presynaptic membrane, calcium ions flood into the terminal button, action potential depolarizes the membrane
What is the role of synaptotagmin in synaptic transmission?
What is the role of synaptotagmin in synaptic transmission?
- It acts as a calcium sensor and binds to proteins (SNARES) that cause the vesicle to dock and bind to the presynaptic terminal membrane (correct)
- It depolarizes the membrane of a terminal button, causing voltage-gated calcium channels to open
- It leads to an increase in intracellular ionized calcium
- It triggers the fusion of vesicles containing neurotransmitters with the presynaptic membrane
What happens when an action potential travels down an axon to the terminal buttons?
What happens when an action potential travels down an axon to the terminal buttons?
- The membrane of a terminal button depolarizes, voltage-gated calcium channels open (correct)
- Calcium ions flood into the terminal button, leading to an increase in intracellular ionized calcium
- Vesicles containing neurotransmitters fuse with the presynaptic membrane
- Synaptotagmin binds to proteins (SNARES) that cause the vesicle to dock and bind to the presynaptic terminal membrane
What is the function of calcium ions in synaptic transmission?
What is the function of calcium ions in synaptic transmission?
What is the process by which neurotransmitter is released from the presynaptic terminal membrane?
What is the process by which neurotransmitter is released from the presynaptic terminal membrane?
Which protein identifies the vesicular membrane for recycling after neurotransmitter release?
Which protein identifies the vesicular membrane for recycling after neurotransmitter release?
Which proteins play a key role in synaptic transmission by being found on both the vesicle and nerve terminal membrane?
Which proteins play a key role in synaptic transmission by being found on both the vesicle and nerve terminal membrane?
Which toxin disrupts SNARE proteins and causes spastic paralysis?
Which toxin disrupts SNARE proteins and causes spastic paralysis?
Which toxin prevents the release of excitatory neurotransmitter and causes flaccid paralysis?
Which toxin prevents the release of excitatory neurotransmitter and causes flaccid paralysis?
Where are V-SNARES and T-SNARES found, respectively?
Where are V-SNARES and T-SNARES found, respectively?
Which type of receptors can be found in the postsynaptic membrane?
Which type of receptors can be found in the postsynaptic membrane?
What can the binding of neurotransmitter to receptors in the postsynaptic membrane lead to?
What can the binding of neurotransmitter to receptors in the postsynaptic membrane lead to?
What can an increase in membrane conductance to sodium ions result in?
What can an increase in membrane conductance to sodium ions result in?
