Master Drug Clearance
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Questions and Answers

Which of the following best describes clearance?

  • The rate of drug elimination in terms of the quantity of drug cleared per unit time
  • The rate of drug elimination in terms of the volume of fluid cleared per unit time (correct)
  • The rate of drug elimination in terms of the quantity of drug eliminated per unit time
  • The rate of drug elimination in terms of the volume of fluid eliminated per unit time

What units are commonly used to express clearance?

  • ml/hr or L/min
  • ml/min or L/hr (correct)
  • mg/hr or g/min
  • mg/min or g/hr

If the apparent volume of distribution (VD) of a drug is 50 L and the total body clearance of the drug is 40 ml/min, how much of the 50 L would be cleared of the drug per minute?

  • 90 ml
  • 80 ml
  • 50 ml
  • 40 ml (correct)

What does the total body clearance consider?

<p>The body as a single drug eliminating system (D)</p> Signup and view all the answers

What is the volume of distribution (VD) of a drug if 30 ml of the 40 L is cleared of the drug per minute?

<p>70 L (A)</p> Signup and view all the answers

Which two major organs are responsible for drug elimination?

<p>Kidneys and liver (C)</p> Signup and view all the answers

What is the term used to describe drug elimination through the kidneys?

<p>Renal clearance (A)</p> Signup and view all the answers

Which physiological factor can affect drug clearance?

<p>Age (D)</p> Signup and view all the answers

Which organ is NOT considered a non-renal pathway of drug elimination?

<p>Lung (C)</p> Signup and view all the answers

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