Podcast
Questions and Answers
Which of the following best describes clearance?
Which of the following best describes clearance?
- The rate of drug elimination in terms of the quantity of drug cleared per unit time
- The rate of drug elimination in terms of the volume of fluid cleared per unit time (correct)
- The rate of drug elimination in terms of the quantity of drug eliminated per unit time
- The rate of drug elimination in terms of the volume of fluid eliminated per unit time
What units are commonly used to express clearance?
What units are commonly used to express clearance?
- ml/hr or L/min
- ml/min or L/hr (correct)
- mg/hr or g/min
- mg/min or g/hr
If the apparent volume of distribution (VD) of a drug is 50 L and the total body clearance of the drug is 40 ml/min, how much of the 50 L would be cleared of the drug per minute?
If the apparent volume of distribution (VD) of a drug is 50 L and the total body clearance of the drug is 40 ml/min, how much of the 50 L would be cleared of the drug per minute?
- 90 ml
- 80 ml
- 50 ml
- 40 ml (correct)
What does the total body clearance consider?
What does the total body clearance consider?
What is the volume of distribution (VD) of a drug if 30 ml of the 40 L is cleared of the drug per minute?
What is the volume of distribution (VD) of a drug if 30 ml of the 40 L is cleared of the drug per minute?
Which two major organs are responsible for drug elimination?
Which two major organs are responsible for drug elimination?
What is the term used to describe drug elimination through the kidneys?
What is the term used to describe drug elimination through the kidneys?
Which physiological factor can affect drug clearance?
Which physiological factor can affect drug clearance?
Which organ is NOT considered a non-renal pathway of drug elimination?
Which organ is NOT considered a non-renal pathway of drug elimination?
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