Master Drug Clearance
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Questions and Answers

Which of the following best describes clearance?

  • The rate of drug elimination in terms of the quantity of drug cleared per unit time
  • The rate of drug elimination in terms of the volume of fluid cleared per unit time (correct)
  • The rate of drug elimination in terms of the quantity of drug eliminated per unit time
  • The rate of drug elimination in terms of the volume of fluid eliminated per unit time

    • What units are commonly used to express clearance?

  • ml/hr or L/min
  • ml/min or L/hr (correct)
  • mg/hr or g/min
  • mg/min or g/hr

    • If the apparent volume of distribution (VD) of a drug is 50 L and the total body clearance of the drug is 40 ml/min, how much of the 50 L would be cleared of the drug per minute?

  • 90 ml
  • 80 ml
  • 50 ml
  • 40 ml (correct)

    • What does the total body clearance consider?

    <p>The body as a single drug eliminating system</p> Signup and view all the answers

    What is the volume of distribution (VD) of a drug if 30 ml of the 40 L is cleared of the drug per minute?

    <p>70 L</p> Signup and view all the answers

    Which two major organs are responsible for drug elimination?

    <p>Kidneys and liver</p> Signup and view all the answers

    What is the term used to describe drug elimination through the kidneys?

    <p>Renal clearance</p> Signup and view all the answers

    Which physiological factor can affect drug clearance?

    <p>Age</p> Signup and view all the answers

    Which organ is NOT considered a non-renal pathway of drug elimination?

    <p>Lung</p> Signup and view all the answers

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